Prolonged RNA interference therapy with ARC-520 Injection in treatment naïve, HBeAg positive and negative patients with chronic HBV results in significant reductions of HBs antigen... von Yuen, M.-F, Liu, K, Chan, H.L, Given, B.D, Schluep, T, Hamilton, J, Lai, C.-L, Locarnini, S.A, Lau, J.Y, Ferrari, C, Gish, R.G

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A phase 1 study to evaluate safety and tolerability of escalating single doses of the hepatitis B virus RNA interference drug ARC-521 in a healthy volunteer population von Gane, E, Schwabe, C, Given, B, Schluep, T, Hamilton, J, Lai, C.-L, Locarnini, S, Lau, J, Ferrari, C, Gish, R

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Predicting HBsAg Clearance Responses during ARC-520 RNA Interference (RNAI) Therapy Based on HBsAg Epitope Profile Analysis von Walsh, R, Hammond, R, Yuen, L, Deerain, J, Given, B, Schluep, T, Yuen, M.-F, Chan, H.L.-Y, Lai, C.-L, Hamilton, J, Lau, J.Y, Ferrari, C, Gish, R.G, Locarnini, S.A

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Differential Reductions in Viral Antigens Expressed from CCCDNAVS Integrated DNA in Treatment Naïve HBEAG Positive and Negative Patients with Chronic HBV after RNA Interference The... von Yuen, M.-F, Chan, H.L.Y, Liu, K, Given, B.D, Schluep, T, Hamilton, J, Lai, C.-L, Locarnini, S.A, Lau, J.Y.N, Ferrari, C, Gish, R.G

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Purification of plasmids by triplex affinity interaction von Schluep, Thomas, Cooney, Charles L.

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Preclinical Efficacy of the Camptothecin-Polymer Conjugate IT-101 in Multiple Cancer Models von SCHLUEP, Thomas, HWANG, Jungyeong, JIANJUN CHENG, HEIDEL, Jeremy D, BARTLETT, Derek W, HOLLISTER, Beth, DAVIS, Mark E

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423 Phase 1 dose escalation, safety and pharmacokinetic study of IT-101 (CRLX101), a novel nanopharmaceutical containing camptothecin, in advanced solid tumor cancer patients von Yen, Y, Synold, T, Weiss, G.J, Schluep, T, Ryan, J

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Cyclodextrin-Containing Polymers: Versatile Platforms of Drug Delivery Materials von Heidel, Jeremy D., Schluep, Thomas

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Serum Neurofilament light: A biomarker of neuronal damage in multiple sclerosis von Disanto, Giulio, Barro, Christian, Benkert, Pascal, Naegelin, Yvonne, Schädelin, Sabine, Giardiello, Antonella, Zecca, Chiara, Blennow, Kaj, Zetterberg, Henrik, Leppert, David, Kappos, Ludwig, Gobbi, Claudio, Kuhle, Jens, Kuhle, Jens, Lorscheider, Johannes, Yaldizli, Özgür, Derfuss, Tobias, Kappos, Ludwig, Disanto, Giulio, Zecca, Chiara, Gobbi, Claudio, Benkert, Pascal, Achtnichts, Lutz, Nedeltchev, Krassen, Kamm, Christian P, Salmen, Anke, Chan, Andrew, Lalive, Patrice H, Pot, Caroline, Schluep, Myriam, Granziera, Cristina, Du Pasquier, Renaud, Müller, Stefanie, Vehoff, Jochen

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Development of subcutaneously administered RNAi therapeutic ARO-HBV for chronic hepatitis B virus infection von Wooddell, C., Zhu, R., Hamilton, H., Chu, Q., Sternard, H., Schumacher, J., Schluep, T., Seefeld, M., Li, Z., Given, B.

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PS-030 - Development of subcutaneously administered RNAi therapeutic ARO-HBV for chronic hepatitis B virus infection von Wooddell, C., Zhu, R., Hamilton, H., Chu, Q., Sternard, H., Schumacher, J., Schluep, T., Seefeld, M., Li, Z., Given, B.

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Cyclodextrin-Modified Polyethylenimine Polymers for Gene Delivery von Pun, Suzie H, Bellocq, Nathalie C, Liu, Aijie, Jensen, Greg, Machemer, Todd, Quijano, Erlinda, Schluep, Thomas, Wen, Shufen, Engler, Heidrun, Heidel, Jeremy, Davis, Mark E

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FRI-362 - RNA interference therapy with ARC-520 Injection results in long term off-therapy antigen reductions in treatment naïve, HBeAg positive and negative patients with chronic... von Yuen, M.-F., Liu, K., Given, B., Schluep, T., Hamilton, J., Lai, C.L., Locarnini, S., Jackson, K., Lau, J.Y., Ferrari, C., Gish, R.G.

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RNA interference therapy with ARC-520 Injection results in long term off-therapy antigen reductions in treatment naïve, HBeAg positive and negative patients with chronic HBV von Yuen, M.-F., Liu, K., Given, B., Schluep, T., Hamilton, J., Lai, C.L., Locarnini, S., Jackson, K., Lau, J.Y., Ferrari, C., Gish, R.G.

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Pharmacokinetics and biodistribution of the camptothecin-polymer conjugate IT-101 in rats and tumor-bearing mice von SCHLUEP, Thomas, JIANJUN CHENG, KHIN, Kay T, DAVIS, Mark E

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Transitioning to Decent Work and Economic Growth

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PS-045 - Prolonged RNA interference therapy with ARC-520 Injection in treatment naïve, HBeAg positive and negative patients with chronic HBV results in significant reductions of HB... von Yuen, M.-F., Liu, K., Chan, H.L., Given, B.D., Schluep, T., Hamilton, J., Lai, C.-L., Locarnini, S.A., Lau, J.Y., Ferrari, C., Gish, R.G.

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THU-176 - A phase 1 study to evaluate safety and tolerability of escalating single doses of the hepatitis B virus RNA interference drug ARC-521 in a healthy volunteer population von Gane, E., Schwabe, C., Given, B., Schluep, T., Hamilton, J., Lai, C.-L., Locarnini, S., Lau, J., Ferrari, C., Gish, R.

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Transitioning to Decent Work and Economic Growth

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THU-193 - Differential Reductions in Viral Antigens Expressed from CCCDNAVS Integrated DNA in Treatment Naïve HBEAG Positive and Negative Patients with Chronic HBV after RNA Interf... von Yuen, M.-F., Chan, H.L.Y., Liu, K., Given, B.D., Schluep, T., Hamilton, J., Lai, C.-L., Locarnini, S.A., Lau, J.Y.N., Ferrari, C., Gish, R.G.

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