BiTEs: bispecific antibody constructs with unique anti-tumor activity von Wolf, Evelyn, Hofmeister, Robert, Kufer, Peter, Schlereth, Bernd, Baeuerle, Patrick A.

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Safety and immunogenicity of IMVAMUNE, a promising candidate as a third generation smallpox vaccine von Vollmar, Jens, Arndtz, Nathaly, Eckl, Karl M., Thomsen, Torben, Petzold, Barbara, Mateo, Luis, Schlereth, Bernd, Handley, Amanda, King, Lynette, Hülsemann, Vanessa, Tzatzaris, Maria, Merkl, Karin, Wulff, Niels, Chaplin, Paul

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Strictly Target Cell-dependent Activation of T Cells by Bispecific Single-chain Antibody Constructs of the BiTE Class von BRISCHWEIN, Klaus, PARR, Larissa, SCHLERETH, Bernd, BAEUERLE, Patrick A, PFLANZ, Stefan, VOLKLAND, Jörg, LUMSDEN, John, KLINGER, Matthias, LOCHER, Mathias, HAMMOND, Scott A, KIENER, Peter, KUFER, Peter

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MT110: A novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors von Brischwein, Klaus, Schlereth, Bernd, Guller, Benjamin, Steiger, Carola, Wolf, Andreas, Lutterbuese, Ralf, Offner, Sonja, Locher, Mathias, Urbig, Thomas, Raum, Tobias, Kleindienst, Petra, Wimberger, Pauline, Kimmig, Rainer, Fichtner, Iduna, Kufer, Peter, Hofmeister, Robert, da Silva, Antonio J., Baeuerle, Patrick A.

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Eradication of tumors from a human colon cancer cell line and from ovarian cancer metastases in immunodeficient mice by a single-chain Ep-CAM-/CD3-bispecific antibody construct von SCHLERETH, Bernd, FICHTNER, Iduna, WIMBERGER, Pauline, KIMMIG, Rainer, BAEUERLE, Patrick A, LORENCZEWSKI, Grit, KLEINDIENST, Petra, BRISCHWEIN, Klaus, DA SILVA, Antonio, KUFER, Peter, LUTTERBUESE, Ralf, JUNGHAHN, Ilse, KASIMIR-BAUER, Sabine

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T Cell Costimulus-Independent and Very Efficacious Inhibition of Tumor Growth in Mice Bearing Subcutaneous or Leukemic Human B Cell Lymphoma Xenografts by a CD19-/CD3- Bispecific S... von Dreier, Torsten, Baeuerle, Patrick A, Fichtner, Iduna, Grun, Michael, Schlereth, Bernd, Lorenczewski, Grit, Kufer, Peter, Lutterbuse, Ralf, Riethmuller, Gert, Gjorstrup, Per, Bargou, Ralf C

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Potent Control of Tumor Growth by CEA/CD3-bispecific Single-chain Antibody Constructs That Are Not Competitively Inhibited by Soluble CEA von LUTTERBUESE, Ralf, RAUM, Tobias, MULGREW, Kathy, OBERST, Michael D, HAMMOND, Scott A, BAEUERLE, Patrick A, KUFER, Peter, KISCHEL, Roman, LUTTERBUESE, Petra, SCHLERETH, Bernd, SCHALLER, Evelyne, MANGOLD, Susanne, RAU, Doris, MEIER, Petra, KIENER, Peter A

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T-cell activation and B-cell depletion in chimpanzees treated with a bispecific anti-CD19/anti-CD3 single-chain antibody construct von SCHLERETH, Bernd, QUADT, Cornelia, LEO, Eugen, BARGOU, Ralf, MURTHY, Krishna, BAEUERLE, Patrick A, DREIER, Torsten, KUFER, Peter, LORENCZEWSKI, Grit, PRANG, Nadja, BRANDL, Christian, LIPPOLD, Sandra, COBB, Kathy, BRASKY, Kathleen

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Antitumor Activity of an EpCAM/CD3-bispecific BiTE Antibody During Long-term Treatment of Mice in the Absence of T-cell Anergy and Sustained Cytokine Release von AMANN, Maria, DARGOUGES, Sandrine, RAUM, Tobias, MÜNZ, Markus, KUFER, Peter, SCHLERETH, Bernd, BAEUERLE, Patrick A, FRIEDRICH, Matthias, LORENCZEWSKI, Grit, BRISCHWEIN, Klaus, KISCHEL, Roman, LUTTERBUESE, Ralf, MANGOLD, Susanne, RAY, Doris, VOLKLAND, Jörg, PFLANZ, Stefan

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Potent inhibition of local and disseminated tumor growth in immunocompetent mouse models by a bispecific antibody construct specific for Murine CD3 von SCHLERETH, Bernd, KLEINDIENST, Petra, KUFER, Peter, BAEUERLE, Patrick A, FICHTNER, Iduna, LORENCZEWSKI, Grit, BRISCHWEIN, Klaus, LIPPOLD, Sandra, DA SILVA, Antonio, LOCHER, Mathias, KISCHEL, Roman, LUTTERBIISE, Ralf

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Successful Vaccine-Induced Seroconversion by Single-Dose Immunization in the Presence of Measles Virus-Specific Maternal Antibodies von Schlereth, B, Rose, J K, Buonocore, L, ter Meulen, V, Niewiesk, S

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Successful mucosal immunization of cotton rats in the presence of measles virus-specific antibodies depends on degree of attenuation of vaccine vector and virus dose von Schlereth, Bernd, Buonocore, Linda, Tietz, Annette, Meulen, Volker ter, Rose, John K, Niewiesk, Stefan

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Vaccination with recombinant modified vaccinia virus Ankara protects against measles virus infection in the mouse and cotton rat model von Weidinger, Gerald, Ohlmann, Marion, Schlereth, Bernd, Sutter, Gerd, Niewiesk, Stefan

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DNA vaccination with both the haemagglutinin and fusion proteins but not the nucleocapsid protein protects against experimental measles virus infection von Schlereth, Bernd, Germann,, Paul-Georg, ter Meulen, Volker, Niewiesk, Stefan

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200 POSTER Strictly target cell-dependent activation of T cells by bispecific single-chain antibody constructs of the BITE class von Brischwein, K., Parr, L., Pflanz, S., Volkland, J., Lumsden, J., Klinger, M., Schlereth, B., Locher, M., Kufer, P., Baeuerle, P.A.

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224 POSTER Characterization of a murine EpCAM/CD3-bispecific BiTE molecule as a surrogate for preclinical development of the human EpCAM/CD3-bispecific BiTE molecule MT110 von Schlereth, B., Brischwein, K., Lutterbuese, P., Parr, L., Lorenczewski, G., Aman, M., Kischel, R., Kufer, P., Locher, M., Baeuerle, P.A.

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Ex vivo Therapie maligner Pleuraergüsse beim metastasierten Mammakarzinom mit dem bispezifischen anti EpCAM/CD3 Antikörper MT110 von Witthauer, Juliane, Schlereth, B., Brischwein, K., Funke, I., Jauch, K. -W., Baeuerle, P., Mayer, Barbara

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Kinetics of deactivation on Cu/ZnO/Al2O3 methanol synthesis catalysts von Fichtl, Matthias B., Schlereth, David, Jacobsen, Nikolas, Kasatkin, Igor, Schumann, Julia, Behrens, Malte, Schlögl, Robert, Hinrichsen, Olaf

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Bimodular Auxin Response Controls Organogenesis in Arabidopsis von De Smet, Ive, Lau, Steffen, Voß, Ute, Vanneste, Steffen, Benjamins, René, Rademacher, Eike H., Schlereth, Alexandra, De Rybel, Bert, Vassileva, Valya, Grunewald, Wim, Naudts, Mirande, Levesque, Mitchell P., Ehrismann, Jasmin S., Inzé, Dirk, Luschnig, Christian, Benfey, Philip N., Weijers, Dolf, Van Montagu, Marc C. E., Bennett, Malcolm J., Jürgens, Gerd, Beeckman, Tom

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BNT162b vaccines protect rhesus macaques from SARS-CoV-2 von Vogel, Annette B., Kanevsky, Isis, Che, Ye, Swanson, Kena A., Muik, Alexander, Vormehr, Mathias, Kranz, Lena M., Walzer, Kerstin C., Hein, Stephanie, Güler, Alptekin, Loschko, Jakob, Maddur, Mohan S., Ota-Setlik, Ayuko, Tompkins, Kristin, Cole, Journey, Lui, Bonny G., Ziegenhals, Thomas, Plaschke, Arianne, Eisel, David, Dany, Sarah C., Fesser, Stephanie, Erbar, Stephanie, Bates, Ferdia, Schneider, Diana, Jesionek, Bernadette, Sänger, Bianca, Wallisch, Ann-Kathrin, Feuchter, Yvonne, Junginger, Hanna, Krumm, Stefanie A., Heinen, André P., Adams-Quack, Petra, Schlereth, Julia, Schille, Stefan, Kröner, Christoph, de la Caridad Güimil Garcia, Ramón, Hiller, Thomas, Fischer, Leyla, Sellers, Rani S., Choudhary, Shambhunath, Gonzalez, Olga, Vascotto, Fulvia, Gutman, Matthew R., Fontenot, Jane A., Hall-Ursone, Shannan, Brasky, Kathleen, Griffor, Matthew C., Han, Seungil, Su, Andreas A. H., Lees, Joshua A., Nedoma, Nicole L., Mashalidis, Ellene H., Sahasrabudhe, Parag V., Tan, Charles Y., Pavliakova, Danka, Singh, Guy, Fontes-Garfias, Camila, Pride, Michael, Scully, Ingrid L., Ciolino, Tara, Obregon, Jennifer, Gazi, Michal, Carrion, Ricardo, Alfson, Kendra J., Kalina, Warren V., Kaushal, Deepak, Shi, Pei-Yong, Klamp, Thorsten, Rosenbaum, Corinna, Kuhn, Andreas N., Türeci, Özlem, Dormitzer, Philip R., Jansen, Kathrin U., Sahin, Ugur

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