Abstract 3321: Using NLPs to study EGFR structure, activation, and inhibition von Scharadin, Tiffany M., Saldana, Matthew, Schlein, Michael, Hoang-Phou, Steven, Trans, Denise, Chang, Dennis, He, Wei, Lam, Kit, Carraway, Kermit L., Coleman, Matthew A., Henderson, Paul T.

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LABEL-FREE DETECTION OF MACROMOLECULES BINDING TO COMPOUND LIBRARIES von Schlein Michael, Lam Kit S

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Accuracy and the effect of possible subject-based confounders of magnitude-based MRI for estimating hepatic proton density fat fraction in adults, using MR spectroscopy as referenc... von Heba, Elhamy R., Desai, Ajinkya, Zand, Kevin A., Hamilton, Gavin, Wolfson, Tanya, Schlein, Alexandra N., Gamst, Anthony, Loomba, Rohit, Sirlin, Claude B., Middleton, Michael S.

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Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity von Chen, Yong, Buyel, Joschka J., Hanssen, Mark J. W., Siegel, Franziska, Pan, Ruping, Naumann, Jennifer, Schell, Michael, van der Lans, Anouk, Schlein, Christian, Froehlich, Holger, Heeren, Joerg, Virtanen, Kirsi A., van Marken Lichtenbelt, Wouter, Pfeifer, Alexander

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Magnetic resonance elastography measured shear stiffness as a biomarker of fibrosis in pediatric nonalcoholic fatty liver disease von Schwimmer, Jeffrey B., Behling, Cynthia, Angeles, Jorge Eduardo, Paiz, Melissa, Durelle, Janis, Africa, Jonathan, Newton, Kimberly P., Brunt, Elizabeth M., Lavine, Joel E., Abrams, Stephanie H., Masand, Prakash, Krishnamurthy, Rajesh, Wong, Kelvin, Ehman, Richard L., Yin, Meng, Glaser, Kevin J., Dzyubak, Bogdan, Wolfson, Tanya, Gamst, Anthony C., Hooker, Jonathan, Haufe, William, Schlein, Alexandra, Hamilton, Gavin, Middleton, Michael S., Sirlin, Claude B.

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Comparative diagnostic performance of ultrasound shear wave elastography and magnetic resonance elastography for classifying fibrosis stage in adults with biopsy-proven nonalcoholi... von Zhang, Yingzhen N., Fowler, Kathryn J., Boehringer, Andrew S., Montes, Vivian, Schlein, Alexandra N., Covarrubias, Yesenia, Wolfson, Tanya, Hong, Cheng W., Valasek, Mark A., Andre, Michael P., Loomba, Rohit, Sirlin, Claude B.

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The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue von Lynes, Matthew D, Leiria, Luiz O, Lundh, Morten, Bartelt, Alexander, Shamsi, Farnaz, Huang, Tian Lian, Takahashi, Hirokazu, Hirshman, Michael F, Schlein, Christian, Lee, Alexandra, Baer, Lisa A, May, Francis J, Gao, Fei, Narain, Niven R, Chen, Emily Y, Kiebish, Michael A, Cypess, Aaron M, Blüher, Matthias, Goodyear, Laurie J, Hotamisligil, Gökhan S, Stanford, Kristin I, Tseng, Yu-Hua

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MR elastography in nonalcoholic fatty liver disease: inter-center and inter-analysis-method measurement reproducibility and accuracy at 3T von Tang, An, Dzyubak, Bogdan, Yin, Meng, Schlein, Alexandra, Henderson, Walter C., Hooker, Jonathan C., Delgado, Timoteo I., Middleton, Michael S., Zheng, Lin, Wolfson, Tanya, Gamst, Anthony, Loomba, Rohit, Ehman, Richard L., Sirlin, Claude B.

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Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution von Schlein, Christian, Fischer, Alexander W., Sass, Frederike, Worthmann, Anna, Tödter, Klaus, Jaeckstein, Michelle Y., Behrens, Janina, Lynes, Matthew D., Kiebish, Michael A., Narain, Niven R., Bussberg, Val, Darkwah, Abena, Jespersen, Naja Zenius, Nielsen, Søren, Scheele, Camilla, Schweizer, Michaela, Braren, Ingke, Bartelt, Alexander, Tseng, Yu-Hua, Heeren, Joerg, Scheja, Ludger

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Accuracy of PDFF estimation by magnitude‐based and complex‐based MRI in children with MR spectroscopy as a reference von Haufe, William M., Wolfson, Tanya, Hooker, Catherine A., Hooker, Jonathan C., Covarrubias, Yesenia, Schlein, Alex N., Hamilton, Gavin, Middleton, Michael S., Angeles, Jorge E., Hernando, Diego, Reeder, Scott B., Schwimmer, Jeffrey B., Sirlin, Claude B.

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The relationship between liver triglyceride composition and proton density fat fraction as assessed by 1 H MRS von Hamilton, Gavin, Schlein, Alex N, Wolfson, Tanya, Cunha, Guilherme M, Fowler, Kathryn J, Middleton, Michael S, Loomba, Rohit, Sirlin, Claude B

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The relationship between liver triglyceride composition and proton density fat fraction as assessed by 1H MRS von Hamilton, Gavin, Schlein, Alex N., Wolfson, Tanya, Cunha, Guilherme M., Fowler, Kathryn J., Middleton, Michael S., Loomba, Rohit, Sirlin, Claude B.

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Accuracy of common proton density fat fraction thresholds for magnitude- and complex-based chemical shift-encoded MRI for assessing hepatic steatosis in patients with obesity von Cunha, Guilherme Moura, Thai, Tydus T., Hamilton, Gavin, Covarrubias, Yesenia, Schlein, Alexandra, Middleton, Michael S., Wiens, Curtis N., McMillan, Alan, Agni, Rashmi, Funk, Luke M., Campos, Guilherme M., Horgan, Santiago, Jacobson, Garth, Wolfson, Tanya, Gamst, Anthony, Schwimmer, Jeffrey B., Reeder, Scott B., Sirlin, Claude B.

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Repeatability and accuracy of various region-of-interest sampling strategies for hepatic MRI proton density fat fraction quantification von Hong, Cheng William, Cui, Jennifer Y., Batakis, Danielle, Xu, Yang, Wolfson, Tanya, Gamst, Anthony C., Schlein, Alexandra N., Negrete, Lindsey M., Middleton, Michael S., Hamilton, Gavin, Loomba, Rohit, Schwimmer, Jeffrey B., Fowler, Kathryn J., Sirlin, Claude B.

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Multicenter Validation of Association Between Decline in MRI‐PDFF and Histologic Response in NASH von Loomba, Rohit, Sanyal, Arun, Chalasani, Naga, Diehl, Anna Mae, Kowdley, Kris, Dasarathy, Srinivasan, Kleiner, David, Behling, Cynthia, Van Natta, Mark, Middleton, Michael, Tonascia, James, Sirlin, Claude, Allende, Daniela, McCullough, Arthur J., Penumatsa, Revathi, Dasarathy, Jaividhya, Bashir, Mustafa, Buie, Stephanie, Diehl, Anna Mae, Guy, Cynthia, Kigongo, Christopher, Kopping, Mariko, Malik, David, Piercy, Dawn, Chalasani, Naga, Cummings, Oscar W., Ragozzino, Linda, Sandrasegaran, Kumar, Vuppalanchi, Raj, Brunt, Elizabeth M., Carpenter, Danielle, Freebersyser, Janet, King, Debra, Lai, Jinping, Neuschwander‐Tetri, Brent A., Siegner, Joan, Stewart, Susan, Torretta, Susan, Wriston, Kristina, Davila, Jodie, Jhaveri, Manan, Kowdley, Kris V., Mukhtar, Nizar, Ness, Erik, Poitevin, Michelle, Quist, Brook, Soo, Sherilynn, Behling, Cynthia, Bhatt, Archana, Loomba, Rohit, Middleton, Michael S., Akhter, Maheen F., Bass, Nathan M., Brandman, Danielle, Gill, Ryan, Hameed, Bilal, Maher, Jacqueline, Terrault, Norah, Ungermann, Ashley, Yeh, Matthew, Boyett, Sherry, Contos, Melissa J., Kirwin, Sherri, Puri, Puneet, Sanyal, Arun J., Schlosser, Jolene, Siddiqui, Mohammad S., Yost‐Schomer, Leslie, Brunt, Elizabeth M., Fowler, Kathryn, Kleiner, David E., Doo, Edward C., Hall, Sherry, Robuck, Patricia R., Torrance, Rebecca, Dodge, John, Isaacson, Milana, Lazo, Mariana, Meinert, Jill, Sharkey, Emily P., Smith, Jacqueline, Smith, Michael, Sternberg, Alice, Tonascia, James, Van Natta, Mark L., Wagoner, Annette, Wilson, Laura A., Yamada, Goro, Yates, Katherine, Gamst, Anthony, Hamilton, Gavin, Henderson, Walter, Hooker, Jonathan, Lavine, Joel E., Middleton, Michael S., Schlein, Alexandria, Schwimmer, Jeffrey B., Shen, Wei, Sirlin, Claude, Wolfson, Tanya

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Synergistic and targeted therapy with a procaspase-3 activator and temozolomide extends survival in glioma rodent models and is feasible for the treatment of canine malignant gliom... von Joshi, Avadhut D, Botham, Rachel C, Schlein, Lisa J, Roth, Howard S, Mangraviti, Antonella, Borodovsky, Alexandra, Tyler, Betty, Joslyn, Steve, Looper, Jayme S, Podell, Michael, Fan, Timothy M, Hergenrother, Paul J, Riggins, Gregory J

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Reader agreement and accuracy of ultrasound features for hepatic steatosis von Hong, Cheng William, Marsh, Austin, Wolfson, Tanya, Paige, Jeremy, Dekhordy, Soudabeh Fazeli, Schlein, Alexandra N., Housman, Elise, Deiranieh, Lisa H., Li, Charles Q., Wasnik, Ashish P., Jang, Hyun-Jung, Dietrich, Christoph F., Piscaglia, Fabio, Casola, Giovanna, O’Boyle, Mary, Richman, Katherine M., Valasek, Mark A., Andre, Michael, Loomba, Rohit, Sirlin, Claude B.

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Hepatic Steatosis is Negatively Associated with Bone Mineral Density in Children von Chun, Lauren F., Yu, Elizabeth L., Sawh, Mary Catherine, Bross, Craig, Nichols, Jeanne, Polgreen, Lynda, Knott, Cynthia, Schlein, Alexandra, Sirlin, Claude B., Middleton, Michael S., Kado, Deborah M., Schwimmer, Jeffrey B.

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In vivo triglyceride composition of abdominal adipose tissue measured by 1H MRS at 3T von Hamilton, Gavin, Schlein, Alexandra N., Middleton, Michael S., Hooker, Catherine A., Wolfson, Tanya, Gamst, Anthony C., Loomba, Rohit, Sirlin, Claude B.

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In vivo triglyceride composition of abdominal adipose tissue measured by 1 H MRS at 3T von Hamilton, Gavin, Schlein, Alexandra N, Middleton, Michael S, Hooker, Catherine A, Wolfson, Tanya, Gamst, Anthony C, Loomba, Rohit, Sirlin, Claude B

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