Lagging strand gap suppression connects BRCA-mediated fork protection to nucleosome assembly through PCNA-dependent CAF-1 recycling von Thakar, Tanay, Dhoonmoon, Ashna, Straka, Joshua, Schleicher, Emily M., Nicolae, Claudia M., Moldovan, George-Lucian

Volltext

Loss of MED12 activates the TGFβ pathway to promote chemoresistance and replication fork stability in BRCA-deficient cells von Jackson, Lindsey M, Dhoonmoon, Ashna, Hale, Anastasia, Dennis, Kady A, Schleicher, Emily M, Nicolae, Claudia M, Moldovan, George-Lucian

Volltext

PARP10 promotes cellular proliferation and tumorigenesis by alleviating replication stress von Schleicher, Emily M, Galvan, Adri M, Imamura-Kawasawa, Yuka, Moldovan, George-Lucian, Nicolae, Claudia M

Volltext

CRISPR screens guide the way for PARP and ATR inhibitor biomarker discovery von Schleicher, Emily M., Moldovan, George‐Lucian

Volltext

Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens von Clements, Kristen E., Schleicher, Emily M., Thakar, Tanay, Hale, Anastasia, Dhoonmoon, Ashna, Tolman, Nathanial J., Sharma, Anchal, Liang, Xinwen, Imamura Kawasawa, Yuka, Nicolae, Claudia M., Wang, Hong-Gang, De, Subhajyoti, Moldovan, George-Lucian

Volltext

Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in DNA replication dynamics controlled by ATR von Dhoonmoon, Ashna, Schleicher, Emily M, Clements, Kristen E, Nicolae, Claudia M, Moldovan, George-Lucian

Volltext

Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors von Schleicher, Emily M, Dhoonmoon, Ashna, Jackson, Lindsey M, Clements, Kristen E, Stump, Coryn L, Nicolae, Claudia M, Moldovan, George-Lucian

Volltext

Tristetraprolin targets Nos2 expression in the colonic epithelium von Eshelman, Melanie A., Matthews, Stephen M., Schleicher, Emily M., Fleeman, Rebecca M., Kawasawa, Yuka Imamura, Stumpo, Deborah J., Blackshear, Perry J., Koltun, Walter A., Ishmael, Faoud T., Yochum, Gregory S.

Volltext

Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival von Khatib, Jude B., Schleicher, Emily M., Jackson, Lindsey M., Dhoonmoon, Ashna, Moldovan, George-Lucian, Nicolae, Claudia M.

Volltext

PARI (PARPBP) suppresses replication stress-induced myeloid differentiation in leukemia cells von Nicolae, Claudia M., O’Connor, Michael J., Schleicher, Emily M., Song, Chunhua, Gowda, Raghavendra, Robertson, Gavin, Dovat, Sinisa, Moldovan, George-Lucian

Volltext

Interactions between the WEE-1.3 kinase and the PAM-1 aminopeptidase in oocyte maturation and the early C. elegans embryo von Benton, Dorothy, Jaeger, Eva C, Kilner, Arielle, Kimble, Ashley, Lowry, Josh, Schleicher, Emily M, Power, Kaiden M, Uibel, Danielle, Eisele, Caprice, Bowerman, Bruce, Lyczak, Rebecca

Volltext

The TIP60-ATM axis regulates replication fork stability in BRCA-deficient cells von Schleicher, Emily M., Dhoonmoon, Ashna, Jackson, Lindsey M., Khatib, Jude B., Nicolae, Claudia M., Moldovan, George-Lucian

Volltext

CRISPR screens guide the way for PARP and ATR inhibitors biomarker discovery von Schleicher, Emily M., Moldovan, George-Lucian

Volltext

Tu1752 - Expression of Tristetraprolin in the Intestinal Epithelium Exacerbates DSS-Induced Colitis von Eshelman, Melanie, Schleicher, Emily, Koltun, Walter, Yochum, Gregory S.

Volltext

PIG-a Gene Expression Deficiency Association with Reduced DNA Damage Checkpoint Response and Activation von Pu, Jeffrey J, Lu, Shasha, Nemesure, Matthew, Teye, Emmanuel Kwame, Schleicher, Emily, Moldovan, George-Lucian, Brodsky, Robert A., Chen, Fangyuan

Volltext

Abstract B062: Loss of MED12 activates the TGFβ pathway to promote chemoresistance and replication fork stability in BRCA-deficient cells von Pale, Lindsey M, Dhoonmoon, Ashna, Hale, Anastasia, Dennis, Kady A, Schleicher, Emily M, Nicolae, Claudia M, Moldovan, George-Lucian

Volltext

Abstract 1708: An integrated framework for genome analysis reveals numerous previously unrecognizable structural variants in leukemia patients’ samples von Broach, James R., Xu, Jie, Schleicher, Emily, Pool, Christopher, Hennessy, Max, Sheldon, Kathryn, Annageldiyev, Charyguly, Sharma, Arati, Chang, Yuanyuan, Hastie, Alex, Miller, Barbara, Goldenberg, David, Claxton, David, Moldovan, George-Lucian, Yue, Feng

Volltext

An Integrated Framework for Genome Analysis Reveals Numerous Previously Unrecognizable Structural Variants in Leukemia Patient Samples von Broach, James, Xu, Jie, Schleicher, Emily, Song, Fan, Pool, Christopher, Hennessy, Max, Sheldon, Kathryn, Annageldiyev, Charyguly, Sharma, Arati, Chang, Yuanyuan, Hastie, Alex, Miller, Barbara, Goldenberg, David, Claxton, David, Moldovan, Geroge‐Lucian, Yue, Feng

Volltext

Supplemental Material for Benton et al., 2021 von Benton, Dorothy, Jaeger, Eva C., Kilner, Arielle, Kimble, Ashley, Lowry, Josh, Schleicher, Emily M., Power, Kaiden M., Uibel, Danielle, Eisele, Caprice, Bowerman, Bruce, Lyczak, Rebecca

Volltext bestellen

Exploring acute-to-chronic neuropathic pain in rats after contusion spinal cord injury von Gaudet, Andrew D., Ayala, Monica T., Schleicher, Wolfgang E., Smith, Elana J., Bateman, Emily M., Maier, Steven F., Watkins, Linda R.

Volltext