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An antidepressant-related pharmacological signature for positive allosteric modulators of α2/3-containing GABA A receptors von Methuku, K R, Li, X, Cerne, R, Gleason, S D, Schkeryantz, J M, Tiruveedhula, V V N P B, Golani, L K, Li, G, Poe, M M, Rahman, Md T, Cook, J M, Fisher, J L, Witkin, J M

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The α2,3-selective potentiator of GABAA receptors, KRM-II-81, reduces nociceptive-associated behaviors induced by formalin and spinal nerve ligation in rats von Witkin, J.M., Cerne, R., Davis, P.G., Freeman, K.B., do Carmo, J.M., Rowlett, J.K., Methuku, K.R., Okun, A., Gleason, S.D., Li, X., Krambis, M.J., Poe, M., Li, G., Schkeryantz, J.M., Jahan, R., Yang, L., Guo, W., Golani, L.K., Anderson, W.H., Catlow, J.T., Jones, T.M., Porreca, F., Smith, J.L., Knopp, K.L., Cook, J.M.

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An antidepressant-related pharmacological signature for positive allosteric modulators of α2/3-containing GABAA receptors von Methuku, K.R., Li, X., Cerne, R., Gleason, S.D., Schkeryantz, J.M., Tiruveedhula, V.V.N.P.B., Golani, L.K., Li, G., Poe, M.M., Rahman, Md.T., Cook, J.M., Fisher, J.L., Witkin, J.M.

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Bioisosteres of ethyl 8-ethynyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo [1,5-a][1,4]diazepine-3-carboxylate (HZ-166) as novel alpha 2,3 selective potentiators of GABAA receptors: Impro... von Witkin, J.M., Smith, J.L., Ping, X., Gleason, S.D., Poe, M.M., Li, G., Jin, X., Hobbs, J., Schkeryantz, J.M., McDermott, J.S., Alatorre, A.I., Siemian, J.N., Cramer, J.W., Airey, D.C., Methuku, K.R., Tiruveedhula, V.V.N.P.B., Jones, T.M., Crawford, J., Krambis, M.J., Fisher, J.L., Cook, J.M., Cerne, R.

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Further evaluation of the potential anxiolytic activity of imidazo[1,5-a][1,4]diazepin agents selective for α2/3-containing GABA A receptors von Witkin, J M, Cerne, R, Wakulchik, M, S, J, Gleason, S D, Jones, T M, Li, G, Arnold, L A, Li, J-X, Schkeryantz, J M, Methuku, K R, Cook, J M, Poe, M M

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