Evaluation of apoptosis stimulating protein of TP53-1 (ASPP1/PPP1R13B) to predict therapy resistance and overall survival in acute myeloid leukemia (AML) von Schittenhelm, Marcus M., Kaiser, Max, Győrffy, Balázs, Kampa-Schittenhelm, Kerstin M.

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Alternative splicing of Apoptosis Stimulating Protein of TP53-2 (ASPP2) results in an oncogenic isoform promoting migration and therapy resistance in soft tissue sarcoma (STS) von Tsintari, Vasileia, Walter, Bianca, Fend, Falko, Overkamp, Mathis, Rothermundt, Christian, Lopez, Charles D., Schittenhelm, Marcus M., Kampa-Schittenhelm, Kerstin M.

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Impact of TP53 Mutation Status in Elderly AML Patients When Adding All-Trans Retinoic Acid or Valproic Acid to Decitabine von Bresser, Helena, Schmoor, Claudia, Grishina, Olga, Pfeifer, Dietmar, Thomas, Johanna, Rehman, Usama-Ur, Crysandt, Martina, Jost, Edgar, Thol, Felicitas, Heuser, Michael, Götze, Katharina S, Schlenk, Richard F, Salih, Helmut R, Schittenhelm, Marcus M, Heil, Gerhard, Schwaenen, Carsten, Müller-Tidow, Carsten, Brugger, Wolfram, Kündgen, Andrea, de Wit, Maike, Giagounidis, Aristoteles, Scholl, Sebastian, Neubauer, Andreas, Krauter, Jürgen, Bug, Gesine, May, Annette M, Wäsch, Ralph, Duyster, Justus, Döhner, Konstanze, Ganser, Arnold, Döhner, Hartmut, Hackanson, Björn, Becker, Heiko, Lübbert, Michael

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Attenuated expression of apoptosis stimulating protein of p53-2 (ASPP2) in human acute leukemia is associated with therapy failure von Schittenhelm, Marcus M, Illing, Barbara, Ahmut, Figen, Rasp, Katharina Henriette, Blumenstock, Gunnar, Döhner, Konstanze, Lopez, Charles D, Kampa-Schittenhelm, Kerstin M

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Identification of Driver and Passenger Mutations of FLT3 by High-Throughput DNA Sequence Analysis and Functional Assessment of Candidate Alleles von Fröhling, Stefan, Scholl, Claudia, Levine, Ross L., Loriaux, Marc, Boggon, Titus J., Bernard, Olivier A., Berger, Roland, Döhner, Hartmut, Döhner, Konstanze, Ebert, Benjamin L., Teckie, Sewit, Golub, Todd R., Jiang, Jingrui, Schittenhelm, Marcus M., Lee, Benjamin H., Griffin, James D., Stone, Richard M., Heinrich, Michael C., Deininger, Michael W., Druker, Brian J., Gilliland, D. Gary

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ASPP2κ Is Expressed In Human Colorectal Carcinoma And Promotes Chemotherapy Resistance And Tumorigenesis von Rieger, Ingmar, Tsintari, Vasileia, Overkamp, Mathis, Fend, Falko, Lopez, Charles D., Schittenhelm, Marcus M., Kampa-Schittenhelm, Kerstin M.

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The FLT3 inhibitor tandutinib (formerly MLN518) has sequence-independent synergistic effects with cytarabine and daunorubicin von Schittenhelm, Marcus M., Kampa, Kerstin M., Yee, Kevin W. H., Heinrich, Michael C.

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Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human mal... von SCHITTENHELM, Marcus M, SHIRAGA, Sharon, SCHROEDER, Arin, CORBIN, Amie S, GRIFFITH, Diana, LEE, Francis Y, BOKEMEYER, Carsten, DEININGER, Michael W. N, DRUKER, Brian J, HEINRICH, Michael C

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Dasatinib overrides the differentiation blockage in a patient with mutant- KIT D816V positive CBFβ-MYH11 leukemia von Kampa-Schittenhelm, Kerstin M, Vogel, Wichard, Bonzheim, Irina, Fend, Falko, Horger, Marius, Kanz, Lothar, Soekler, Martin, Schittenhelm, Marcus M

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Molecular determinants of response to matuzumab in combination with paclitaxel for patients with advanced non-small cell lung cancer von Schittenhelm, Marcus M, Kollmannsberger, Christian, Oechsle, Karin, Harlow, Amy, Morich, Jason, Honecker, Friedemann, Kurek, Raffael, Störkel, Stephan, Kanz, Lothar, Corless, Christopher L, Wong, Kwok-Kin, Bokemeyer, Carsten, Heinrich, Michael C

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Valproate and Retinoic Acid in Combination With Decitabine in Elderly Nonfit Patients With Acute Myeloid Leukemia: Results of a Multicenter, Randomized, 2 × 2, Phase II Trial von Lübbert, Michael, Grishina, Olga, Schmoor, Claudia, Schlenk, Richard F, Jost, Edgar, Crysandt, Martina, Heuser, Michael, Thol, Felicitas, Salih, Helmut R, Schittenhelm, Marcus M, Germing, Ulrich, Kuendgen, Andrea, Götze, Katharina S, Lindemann, Hans-Walter, Müller-Tidow, Carsten, Heil, Gerhard, Scholl, Sebastian, Bug, Gesine, Schwaenen, Carsten, Giagounidis, Aristoteles, Neubauer, Andreas, Krauter, Jürgen, Brugger, Wolfram, De Wit, Maike, Wäsch, Ralph, Becker, Heiko, May, Annette M, Duyster, Justus, Döhner, Konstanze, Ganser, Arnold, Hackanson, Björn, Döhner, Hartmut

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Attenuation of the Apoptosis Stimulating Protein of TP53-1 (ASPP1) Is a Predictive Marker for Therapy Resistance and Overall Survival in Acute Myeloid Leukemia (AML) von Schittenhelm, Marcus M., Kaiser, Max, Tsintari, Vasileia, Blumenstock, Gunnar, Györffy, Balazs, Kampa-Schittenhelm, Kerstin Maria

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ASPP2 k, a Dominant-Negative Splicing Variant of the Apoptosis-Stimulating Protein of p53-2 (ASPP2), Modulates Treatment Response Towards BCL-Signaling Inhibitors in Acute Myeloid... von Schittenhelm, Marcus M., Tsintari, Vasileia, Fröhlich, Rebecca, Kampa-Schittenhelm, Kerstin Maria

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Alternative splicing of Apoptosis Stimulating Protein of TP53-2 von Tsintari, Vasileia, Walter, Bianca, Fend, Falko, Overkamp, Mathis, Rothermundt, Christian, Lopez, Charles D, Schittenhelm, Marcus M, Kampa-Schittenhelm, Kerstin M

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Valproate and Retinoic Acid in Combination With Decitabine in Elderly Nonfit Patients With Acute Myeloid Leukemia: Results of a Multicenter, Randomized, 2 x 2, Phase II Trial von Luebbert, Michael, Grishina, Olga, Schmoor, Claudia, Schlenk, Richard F., Jost, Edgar, Crysandt, Martina, Heuser, Michael, Thol, Felicitas, Salih, Helmut R., Schittenhelm, Marcus M., Germing, Ulrich, Kuendgen, Andrea, Goetze, Katharina S., Lindemann, Hans-Walter, Mueller-Tidow, Carsten, Heil, Gerhard, Scholl, Sebastian, Bug, Gesine, Schwaenen, Carsten, Giagounidis, Aristoteles, Neubauer, Andreas, Krauter, Juergen, Brugger, Wolfram, De Wit, Maike, Waesch, Ralph, Becker, Heiko, May, Annette M., Duyster, Justus, Doehner, Konstanze, Ganser, Arnold, Hackanson, Bjoern, Doehner, Hartmut

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Oncogenic Splicing of the Apoptosis-Stimulating Protein of p53-2 (ASPP2) Is an Initiating Step in Leukemogenesis Facilitating Acquisition of Structural Genomic Mutations von Kampa-Schittenhelm, Kerstin Maria, Mau-Holzmann, Ulrike, Lopez, Charles, Schittenhelm, Marcus M.

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Attenuation of Apoptosis Stimulating Protein of p53-1 (ASPP1) Associates with Therapy Failure in Acute Myeloid Leukemia (AML) von Schittenhelm, Marcus M., Kaiser, Max, Blumenstock, Gunnar, Kampa-Schittenhelm, Kerstin Maria

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Dysregulation of the ASPP Protein Family (Apoptosis Stimulating Proteins of TP53) Is a Common Feature in High-Risk Acute Myeloid Leukemia (AML) von Kampa-Schittenhelm, Kerstin Maria, Kaiser, Max, Bajrami Saipi, Mihada, Walter, Bianca, Blumenstock, Gunnar, Kanz, Lothar, Schittenhelm, Marcus M

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Attenuation of Apoptosis-Stimulating Protein of p53-2 (ASPP2) Promotes IL-3-Independent Growth and Enhances Cytogenetic Abnormalities after Gamma-Irradiation in Mouse Hematopoietic... von Kampa-Schittenhelm, Kerstin Maria, Mau-Holzmann, Ulrike, Kanz, Lothar, Lopez, Charles, Schittenhelm, Marcus M

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ASPP2 Attenuation Is an Early Step in Leukemogenesis Facilitating Acquisition of Mutations von Kampa-Schittenhelm, Kerstin M, Akmut, Figen, Illing, Barbara, Lopez, Charles, Schittenhelm, Marcus M

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