The Crystal Structure of Human Argonaute2 von Schirle, Nicole T., MacRae, Ian J.

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Structural basis for microRNA targeting von Schirle, Nicole T., Sheu-Gruttadauria, Jessica, MacRae, Ian J.

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Structural Basis for Target-Directed MicroRNA Degradation von Sheu-Gruttadauria, Jessica, Pawlica, Paulina, Klum, Shannon M., Wang, Sonia, Yario, Therese A., Schirle Oakdale, Nicole T., Steitz, Joan A., MacRae, Ian J.

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A Dynamic Search Process Underlies MicroRNA Targeting von Chandradoss, Stanley D., Schirle, Nicole T., Szczepaniak, Malwina, MacRae, Ian J., Joo, Chirlmin

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The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins von Shurtleff, Matthew J, Itzhak, Daniel N, Hussmann, Jeffrey A, Schirle Oakdale, Nicole T, Costa, Elizabeth A, Jonikas, Martin, Weibezahn, Jimena, Popova, Katerina D, Jan, Calvin H, Sinitcyn, Pavel, Vembar, Shruthi S, Hernandez, Hilda, Cox, Jürgen, Burlingame, Alma L, Brodsky, Jeffrey L, Frost, Adam, Borner, Georg Hh, Weissman, Jonathan S

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Helix‐7 in Argonaute2 shapes the microRNA seed region for rapid target recognition von Klum, Shannon M, Chandradoss, Stanley D, Schirle, Nicole T, Joo, Chirlmin, MacRae, Ian J

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Structural Analysis of Human Argonaute‑2 Bound to a Modified siRNA Guide von Schirle, Nicole T, Kinberger, Garth A, Murray, Heather F, Lima, Walt F, Prakash, Thazha P, MacRae, Ian J

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Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets von Schirle, Nicole T, Sheu-Gruttadauria, Jessica, Chandradoss, Stanley D, Joo, Chirlmin, MacRae, Ian J

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RNA editing changes the lesion specificity for the DNA repair enzyme NEIL1 von Yeo, Jongchan, Goodman, Rena A., Schirle, Nicole T., David, Sheila S., Beal, Peter A., Barton, Jacqueline

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Structure-Guided Control of siRNA Off-Target Effects von Suter, Scott R, Sheu-Gruttadauria, Jessica, Schirle, Nicole T, Valenzuela, Rachel, Ball-Jones, Alexi A, Onizuka, Kazumitsu, MacRae, Ian J, Beal, Peter A

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Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients von Miller-Vedam, Lakshmi E, Bräuning, Bastian, Popova, Katerina D, Schirle Oakdale, Nicole T, Bonnar, Jessica L, Prabu, Jesuraj R, Boydston, Elizabeth A, Sevillano, Natalia, Shurtleff, Matthew J, Stroud, Robert M, Craik, Charles S, Schulman, Brenda A, Frost, Adam, Weissman, Jonathan S

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Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs von Foss, Dana V., Schirle, Nicole T., MacRae, Ian J., Pezacki, John Paul

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Screening helix-threading peptides for RNA binding using a thiazole orange displacement assay von Krishnamurthy, Malathy, Schirle, Nicole T., Beal, Peter A.

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Potent and Selective Inhibition of A‑to‑I RNA Editing with 2′‑O‑Methyl/Locked Nucleic Acid-Containing Antisense Oligoribonucleotides von Mizrahi, Rena A, Schirle, Nicole T, Beal, Peter A

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Selective inhibition of ADAR2-catalyzed editing of the serotonin 2c receptor pre-mRNA by a helix-threading peptide von Schirle, Nicole T, Goodman, Rena A, Krishnamurthy, Malathy, Beal, Peter A

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Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNA s von Foss, Dana V., Schirle, Nicole T., MacRae, Ian J., Pezacki, John Paul

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Structural analysis of human Argonaute-2 bound to a modified siR-NA guide von Schirle, Nicole T., Kinberger, Garth A., Murray, Heather F., Lima, Walt F., Prakash, Thazha P., MacRae, Ian J.

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Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets - See more at: http://elifesciences.org/content/early/2015/09/11/eLife.07646#sthash.CUHzGKUq.dpuf von Schirle, Nicole T., Sheu-Gruttadauria, Jessica, Chandradoss, Stanley D., Joo, Chirlmin, MacRae, Ian J.

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Structural Basis for Target-Directed MicroRNA Degradation von Sheu-Gruttadauria, Jessica, Pawlica, Paulina, Klum, Shannon M., Wang, Sonia, Yario, Therese A., Schirle Oakdale, Nicole T., Steitz, Joan A., MacRae, Ian J.

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