Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors von Goodman, Krista B., Bury, Michael J., Cheung, Mui, Cichy-Knight, Maria A., Dowdell, Sarah E., Dunn, Allison K., Lee, Dennis, Lieby, Jeffrey A., Moore, Michael L., Scherzer, Daryl A., Sha, Deyou, Suarez, Dominic P., Murphy, Dennis J., Harpel, Mark R., Manas, Eric S., McNulty, Dean E., Annan, Roland S., Matico, Rosalie E., Schwartz, Benjamin K., Trill, John J., Sweitzer, Thomas D., Wang, Da-yuan, Keller, Paul M., Krawiec, John A., Jaye, Michael C.

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Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2 von Verma, Sharad K, Tian, Xinrong, LaFrance, Louis V, Duquenne, Céline, Suarez, Dominic P, Newlander, Kenneth A, Romeril, Stuart P, Burgess, Joelle L, Grant, Seth W, Brackley, James A, Graves, Alan P, Scherzer, Daryl A, Shu, Art, Thompson, Christine, Ott, Heidi M, Aller, Glenn S. Van, Machutta, Carl A, Diaz, Elsie, Jiang, Yong, Johnson, Neil W, Knight, Steven D, Kruger, Ryan G, McCabe, Michael T, Dhanak, Dashyant, Tummino, Peter J, Creasy, Caretha L, Miller, William H

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Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors von Medina, Jesús R, Becker, Christopher J, Blackledge, Charles W, Duquenne, Celine, Feng, Yanhong, Grant, Seth W, Heerding, Dirk, Li, William H, Miller, William H, Romeril, Stuart P, Scherzer, Daryl, Shu, Arthur, Bobko, Mark A, Chadderton, Antony R, Dumble, Melissa, Gardiner, Christine M, Gilbert, Seth, Liu, Qi, Rabindran, Sridhar K, Sudakin, Valery, Xiang, Hong, Brady, Pat G, Campobasso, Nino, Ward, Paris, Axten, Jeffrey M

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Abstract 2939: Discovery and synthesis of highly potent and selective small molecule inhibitors of the histone methyltransferase EZH2 von Verma, Sharad K., LaFrance, Louis V., Tian, Xinrong, Newlander, Ken, Duquenne, Céline, Suarez, Dominic, Knight, Steven D., Burgess, Joelle, Brackley, James, Johnson, Neil W., Graves, Alan P., Mellinger, Mark, Romeril, Stuart, Grant, Seth W., Scherzer, Daryl, Shu, Art, Creasy, Caretha L., Kruger, Ryan, Diaz, Elsie, Le, Baochau, Thompson, Christine, Morgan-Ott, Heidi, McCabe, Michael T., McHugh, Charles F., Miller, William H., Tummino, Peter, Dhanak, Dash

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