Identification of serum proteins discriminating colorectal cancer patients and healthy controls using surface-enhanced laser desorption ionisation-time of flight mass spectrometry von Engwegen, Judith Y M N, Helgason, Helgi H, Cats, Annemieke, Harris, Nathan, Bonfrer, Johannes M G, Schellens, Jan H M, Beijnen, Jos H

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Review of Chromatographic Bioanalytical Assays for the Quantitative Determination of Marine-Derived Drugs for Cancer Treatment von van Andel, Lotte, Rosing, Hilde, Schellens, Jan Hm, Beijnen, Jos H

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Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer von Kopetz, Scott, Grothey, Axel, Yaeger, Rona, Van Cutsem, Eric, Desai, Jayesh, Yoshino, Takayuki, Wasan, Harpreet, Ciardiello, Fortunato, Loupakis, Fotios, Hong, Yong Sang, Steeghs, Neeltje, Guren, Tormod K, Arkenau, Hendrik-Tobias, Garcia-Alfonso, Pilar, Pfeiffer, Per, Orlov, Sergey, Lonardi, Sara, Elez, Elena, Kim, Tae-Won, Schellens, Jan H.M, Guo, Christina, Krishnan, Asha, Dekervel, Jeroen, Morris, Van, Calvo Ferrandiz, Aitana, Tarpgaard, L.S, Braun, Michael, Gollerkeri, Ashwin, Keir, Christopher, Maharry, Kati, Pickard, Michael, Christy-Bittel, Janna, Anderson, Lisa, Sandor, Victor, Tabernero, Josep

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Molecular Pathways: Targeting the Protein Kinase Wee1 in Cancer von Geenen, Jill J J, Schellens, Jan H M

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Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies von Keizer, Ron J., Huitema, Alwin D. R., Schellens, Jan H. M., Beijnen, Jos H.

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Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers von Fong, Peter C, Boss, David S, Yap, Timothy A, Tutt, Andrew, Wu, Peijun, Mergui-Roelvink, Marja, Mortimer, Peter, Swaisland, Helen, Lau, Alan, O'Connor, Mark J, Ashworth, Alan, Carmichael, James, Kaye, Stan B, Schellens, Jan H.M, de Bono, Johann S

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Binimetinib, Encorafenib, and Cetuximab Triplet Therapy for Patients With BRAF V600E-Mutant Metastatic Colorectal Cancer: Safety Lead-In Results From the Phase III BEACON Colorecta... von Van Cutsem, Eric, Huijberts, Sanne, Grothey, Axel, Yaeger, Rona, Cuyle, Pieter-Jan, Elez, Elena, Fakih, Marwan, Montagut, Clara, Peeters, Marc, Yoshino, Takayuki, Wasan, Harpreet, Desai, Jayesh, Ciardiello, Fortunato, Gollerkeri, Ashwin, Christy-Bittel, Janna, Maharry, Kati, Sandor, Victor, Schellens, Jan H M, Kopetz, Scott, Tabernero, Josep

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A phase I study of SAR405838, a novel human double minute 2 (HDM2) antagonist, in patients with solid tumours von de Jonge, Maja, de Weger, Vincent A, Dickson, Mark A, Langenberg, Marlies, Le Cesne, Axel, Wagner, Andrew J, Hsu, Karl, Zheng, Wei, Macé, Sandrine, Tuffal, Gilles, Thomas, Koruth, Schellens, Jan H.M

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Simultaneous quantification of emtricitabine and tenofovir nucleotides in peripheral blood mononuclear cells using weak anion-exchange liquid chromatography coupled with tandem mas... von Jansen, Robert S., Rosing, Hilde, Kromdijk, Wiete, ter Heine, Rob, Schellens, Jan HM, Beijnen, Jos H.

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Thymidylate synthase maintains the de-differentiated state of triple negative breast cancers von Siddiqui, Aarif, Gollavilli, Paradesi Naidu, Schwab, Annemarie, Vazakidou, Maria Eleni, Ersan, Pelin G., Ramakrishnan, Mallika, Pluim, Dick, Coggins, Si’Ana, Saatci, Ozge, Annaratone, Laura, HM Schellens, Jan, Kim, Baek, Asangani, Irfan Ahmed, Rasheed, Suhail Ahmed Kabeer, Marchiò, Caterina, Sahin, Ozgur, Ceppi, Paolo

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Cellular and clinical pharmacology of the taxanes docetaxel and paclitaxel – a review von de Weger, Vincent A, Beijnen, Jos H, Schellens, Jan H.M

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Prospective DPYD genotyping to reduce the risk of fluoropyrimidine-induced severe toxicity: Ready for prime time von Lunenburg, Carin A.T.C, Henricks, Linda M, Guchelaar, Henk-Jan, Swen, Jesse J, Deenen, Maarten J, Schellens, Jan H.M, Gelderblom, Hans

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Piraña and PCluster: A modeling environment and cluster infrastructure for NONMEM von Keizer, Ron J, van Benten, Michel, Beijnen, Jos H, Schellens, Jan H.M, Huitema, Alwin D.R

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Dihydrofolate Reductase/Thymidylate Synthase Fine-Tunes the Folate Status and Controls Redox Homeostasis in Plants von Gorelova, Vera, De Lepeleire, Jolien, Van Daele, Jeroen, Pluim, Dick, Meï, Coline, Cuypers, Ann, Leroux, Olivier, Rébeillé, Fabrice, Schellens, Jan H.M., Blancquaert, Dieter, Stove, Christophe P., Van Der Straeten, Dominique

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Effectiveness and safety of reduced‐dose fluoropyrimidine therapy in patients carrying the DPYD2A variant: A matched pair analysis von Henricks, Linda M., Merendonk, Lisanne N., Meulendijks, Didier, Deenen, Maarten J., Beijnen, Jos H., Boer, Anthonius, Cats, Annemieke, Schellens, Jan H.M.

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Haptoglobin phenotype is not a predictor of recurrence free survival in high-risk primary breast cancer patients von Gast, Marie-Christine W, van Tinteren, Harm, Bontenbal, Marijke, van Hoesel, René Q G C M, Nooij, Marianne A, Rodenhuis, Sjoerd, Span, Paul N, Tjan-Heijnen, Vivianne C G, de Vries, Elisabeth G E, Harris, Nathan, Twisk, Jos W R, Schellens, Jan H M, Beijnen, Jos H

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Relationship between Single Nucleotide Polymorphisms and Haplotypes in DPYD and Toxicity and Efficacy of Capecitabine in Advanced Colorectal Cancer von DEENEN, Maarten J, TOL, Jolien, SCHELLENS, Jan H. M, CATS, Annemieke, BURYLO, Artur M, DOODEMAN, Valerie D, DE BOER, Anthonius, VINCENT, Andrew, GUCHELAAR, Henk-Jan, SMITS, Paul H. M, BEIJNEN, Jos H, PUNT, Cornelis J. A

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Translating DPYD genotype into DPD phenotype: using the DPYD gene activity score von Henricks, Linda M, Lunenburg, Carin A T C, Meulendijks, Didier, Gelderblom, Hans, Cats, Annemieke, Swen, Jesse J, Schellens, Jan H M, Guchelaar, Henk-Jan

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Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drugs von Breedveld, Pauline, Beijnen, Jos H., Schellens, Jan H.M.

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P‐glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel von Hendrikx, Jeroen J.M.A., Lagas, Jurjen S., Rosing, Hilde, Schellens, Jan H.M., Beijnen, Jos H., Schinkel, Alfred H.

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