Nanobody–siRNA Conjugates for Targeted Delivery of siRNA to Cancer Cells von Zavoiura, Oleksandr, Brunner, Bodo, Casteels, Peter, Zimmermann, Luciana, Ozog, Matthias, Boutton, Carlo, Helms, Mike W, Wagenaar, Timothy, Adam, Volker, Peterka, Josefine, Metz-Weidmann, Christiane, Deschaght, Pieter, Scheidler, Sabine, Jahn-Hofmann, Kerstin

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Small Interfering RNAs Containing Dioxane- and Morpholino-Derived Nucleotide Analogues Show Improved Off-Target Profiles and Chirality-Dependent In Vivo Knock-Down von Hofmeister, Armin, Jahn-Hofmann, Kerstin, Brunner, Bodo, Helms, Mike, Metz-Weidmann, Christiane, Krack, Arne, Kurz, Michael, Heubel, Christoph, Scheidler, Sabine

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Novel Dioxane and Morpholino Nucleotide Analogues: Syntheses and RNA‐Hybridization Properties von Hofmeister, Armin, Jahn‐Hofmann, Kerstin, Krack, Arne, Müller, Armin, Kurz, Michael, Scheidler, Sabine

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Syntheses of Morpholine-Based Nucleotide Analogs for Hepatic siRNA Targeting and Stabilization von Hofmeister, Armin, Jahn-Hofmann, Kerstin, Brunner, Bodo, Helms, Mike W, Metz-Weidmann, Christiane, Krack, Arne, Kurz, Michael, Li, Ziyu, Weitzenberg, Merle M, Pflimlin, Elsa, Plettenburg, Oliver, Scheidler, Sabine

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Anti-miR-21 Suppresses Hepatocellular Carcinoma Growth via Broad Transcriptional Network Deregulation von Wagenaar, Timothy R, Zabludoff, Sonya, Ahn, Sung-Min, Allerson, Charles, Arlt, Heike, Baffa, Raffaele, Cao, Hui, Davis, Scott, Garcia-Echeverria, Carlos, Gaur, Rajula, Huang, Shih-Min A, Jiang, Lan, Kim, Deokhoon, Metz-Weidmann, Christiane, Pavlicek, Adam, Pollard, Jack, Reeves, Jason, Rocnik, Jennifer L, Scheidler, Sabine, Shi, Chaomei, Sun, Fangxian, Tolstykh, Tatiana, Weber, William, Winter, Christopher, Yu, Eunsil, Yu, Qunyan, Zheng, Gang, Wiederschain, Dmitri

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Utility of the RIG-I Agonist Triphosphate RNA for Melanoma Therapy von Helms, Mike W, Jahn-Hofmann, Kerstin, Gnerlich, Felix, Metz-Weidmann, Christiane, Braun, Monika, Dietert, Gabriele, Scherer, Petra, Grandien, Kaj, Theilhaber, Joachim, Cao, Hui, Wagenaar, Timothy R, Schnurr, Max M, Endres, Stefan, Wiederschain, Dmitri, Scheidler, Sabine, Rothenfußer, Simon, Brunner, Bodo, König, Lars M

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Abstract 5024: Treatment with synthetic RIG-I agonist triphosphate RNA leads to local and systemic anti-tumor effects in a mouse melanoma tumor model von Helms, Mike W., Parmantier, Eric, Jahn-Hofmann, Kerstin, Gnerlich, Felix, König, Lars, Metz-Weidmann, Christiane, Braun, Monika, Dietert, Gabriele, Grandien, Kaj, Theilhaber, Joachim, Cao, Hui, Wagenaar, Tim, Schnurr, Max, Endres, Stefan, Wiederschain, Dmitri, Scheidler, Sabine, Rothenfusser, Simon, Brunner, Bodo

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Abstract 2489: Sensitivity of liver cancer cell lines to B-catenin knock-down correlates with pathway activation von Ding, Zhihu (Jeff), Shi, Chaomei, Jiang, Lan, Tolstykh, Tatiana, Cao, Hui, Bangari, Dinesh, Ryan, Susan, Jin, Taiguang, Levit, Mikhail, Mamaat, Karl, Yu, Qunyan, Qu, Hui, Hopke, Joern, Cindhuchao, May, Hoffmann, Dietmar, Sun, Fangxian, Helms, Mike, Jahn-Hofmann, Kerstin, Scheidler, Sabine, Fang, Douglas, Schweizer, Liang, Pollard, Jack, Winter, Christopher, Wiederschain, Dmitri

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Oncogenic dependency on β-catenin in liver cancer cell lines correlates with pathway activation von Ding, Zhihu, Shi, Chaomei, Jiang, Lan, Tolstykh, Tatiana, Cao, Hui, Bangari, Dinesh S, Ryan, Susan, Levit, Mikhail, Jin, Taiguang, Mamaat, Karl, Yu, Qunyan, Qu, Hui, Hopke, Joern, Cindhuchao, May, Hoffmann, Dietmar, Sun, Fangxian, Helms, Mike W, Jahn-Hofmann, Kerstin, Scheidler, Sabine, Schweizer, Liang, Fang, Douglas D, Pollard, Jack, Winter, Christopher, Wiederschain, Dmitri

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Abstract 4787: Targeting miR-21 in hepatocellular carcinoma von Zabludoff, Sonya, Wagenaar, Timothy, Adrian, Francisco, Allerson, Charles, Arlt, Heike, Baffa, Raffaele, Bhat, Bal, Cao, Hui, Davis, Scott, Garcia-Echeverria, Carlos, Heermeier, Kathrin, Huang, Shih-Min, Jiang, Lan, Marcusson, Eric, Metz-Weidmann, Christiane, Pavlicek, Adam, Pollard, Jack, Rocnik, Jennifer, Scheidler, Sabine, Shi, Chaomei, Sun, Fangxian, Tolstykh, Tatiana, Yu, Qunyan, Zheng, Gang, Wiederschain, Dmitri

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RAGE-mediated MAPK activation by food-derived AGE and non-AGE products von Zill, Holger, Bek, Stephan, Hofmann, Thomas, Huber, Jochen, Frank, Oliver, Lindenmeier, Michael, Weigle, Bernd, Erbersdobler, Helmut F, Scheidler, Sabine, Busch, Andreas E, Faist, Veronika

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Dietary Bread Crust Advanced Glycation End Products Bind to the Receptor for AGEs in HEK-293 Kidney Cells but Are Rapidly Excreted after Oral Administration to Healthy and Subtotal... von SOMOZA, VERONIKA, LINDENMEIER, MICHAEL, HOFMANN, THOMAS, FRANK, OLIVER, ERBERSDOBLER, HELMUT F., BAYNES, JOHN W., THORPE, SUZANNE R., HEIDLAND, AUGUST, ZILL, HOLGER, BEK, STEPHAN, HUBER, JOCHEN, WEIGLE, THOMAS, SCHEIDLER, SABINE, BUSCH, ANDREAS E., ŠEBEKOVÁ, KATARÍNA

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The Hybrid PAX3-FKHR Fusion Protein of Alveolar Rhabdomyosarcoma Transforms Fibroblasts in Culture von Scheidler, Sabine, Fredericks, William J., Rauscher, Frank J., Barr, Frederic G., Vogt, Peter K.

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Cardioselective KATP Channel Blockers Derived from a New Series of m-Anisamidoethylbenzenesulfonylthioureas von Englert, Heinrich C, Gerlach, Uwe, Goegelein, Heinz, Hartung, Jens, Heitsch, Holger, Mania, Dieter, Scheidler, Sabine

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Cardioselective K ATP Channel Blockers Derived from a New Series of m -Anisamidoethylbenzenesulfonylthioureas von Englert, Heinrich C., Gerlach, Uwe, Goegelein, Heinz, Hartung, Jens, Heitsch, Holger, Mania, Dieter, Scheidler, Sabine

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COMPOSITIONS AND METHODS FOR INHIBITING PCSK9 von RIVAL, Pierrick, BRUNNER, Bodo, JAHN-HOFMANN, Kerstin, SCHEIDLER, Sabine

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COMPOSITIONS AND METHODS FOR INHIBITING PCSK9 von RIVAL, Pierrick, BRUNNER, Bodo, JAHN-HOFMANN, Kerstin, SCHEIDLER, Sabine

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RNA COMPOSITIONS AND METHODS FOR INHIBITING LIPOPROTEIN(A) von HOFMEISTER, Armin, BRUNNER, Bodo, JAHN-HOFMANN, Kerstin, GUILLOT, Etienne, SCHEIDLER, Sabine, FROTTIER, Bertrand, HELMS, Mike

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NOVEL RNA COMPOSITIONS AND METHODS FOR INHIBITING ANGPTL3 von RIVAL, Pierrick, HOFMEISTER, Armin, BRUNNER, Bodo, JAHN-HOFMANN, Kerstin, METZ-WEIDMANN, Christiane, SCHEIDLER, Sabine, HELMS, Mike

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NOVEL RNA COMPOSITIONS AND METHODS FOR INHIBITING ANGPTL3 von RIVAL, Pierrick, HOFMEISTER, Armin, BRUNNER, Bodo, JAHN-HOFMANN, Kerstin, METZ-WEIDMANN, Christiane, SCHEIDLER, Sabine, HELMS, Mike

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