Antibodies in HIV-1 Vaccine Development and Therapy von Klein, Florian, Mouquet, Hugo, Dosenovic, Pia, Scheid, Johannes F., Scharf, Louise, Nussenzweig, Michel C.

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Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization von Klein, Florian, Diskin, Ron, Scheid, Johannes F., Gaebler, Christian, Mouquet, Hugo, Georgiev, Ivelin S., Pancera, Marie, Zhou, Tongqing, Incesu, Reha-Baris, Fu, Brooks Zhongzheng, Gnanapragasam, Priyanthi N.P., Oliveira, Thiago Y., Seaman, Michael S., Kwong, Peter D., Bjorkman, Pamela J., Nussenzweig, Michel C.

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Structural Insights on the Role of Antibodies in HIV-1 Vaccine and Therapy von West, Anthony P., Scharf, Louise, Scheid, Johannes F., Klein, Florian, Bjorkman, Pamela J., Nussenzweig, Michel C.

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Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01 von Zhou, Tongqing, Georgiev, Ivelin, Wu, Xueling, Yang, Zhi-Yong, Dai, Kaifan, Finzi, Andrés, Do Kwon, Young, Scheid, Johannes F, Shi, Wei, Xu, Ling, Yang, Yongping, Zhu, Jiang, Nussenzweig, Michel C, Sodroski, Joseph, Shapiro, Lawrence, Nabel, Gary J, Mascola, John R, Kwong, Peter D

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Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies von Zhou, Tongqing, Zhu, Jiang, Wu, Xueling, Moquin, Stephanie, Zhang, Baoshan, Acharya, Priyamvada, Georgiev, Ivelin S., Altae-Tran, Han R., Chuang, Gwo-Yu, Joyce, M. Gordon, Do Kwon, Young, Longo, Nancy S., Louder, Mark K., Luongo, Timothy, McKee, Krisha, Schramm, Chaim A., Skinner, Jeff, Yang, Yongping, Yang, Zhongjia, Zhang, Zhenhai, Zheng, Anqi, Bonsignori, Mattia, Haynes, Barton F., Scheid, Johannes F., Nussenzweig, Michel C., Simek, Melissa, Burton, Dennis R., Koff, Wayne C., Mullikin, James C., Connors, Mark, Shapiro, Lawrence, Nabel, Gary J., Mascola, John R., Kwong, Peter D.

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Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies von Mouquet, Hugo, Scharf, Louise, Euler, Zelda, Liu, Yan, Eden, Caroline, Scheid, Johannes F., Halper-Stromberg, Ariel, Gnanapragasam, Priyanthi N. P., Spencer, Daniel I. R., Seaman, Michael S., Schuitemaker, Hanneke, Feizi, Ten, Nussenzweig, Michel C., Bjorkman, Pamela J.

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Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs von Hoot, Sam, McGuire, Andrew T, Cohen, Kristen W, Strong, Roland K, Hangartner, Lars, Klein, Florian, Diskin, Ron, Scheid, Johannes F, Sather, D Noah, Burton, Dennis R, Stamatatos, Leonidas

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Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike von Scharf, Louise, Scheid, Johannes F., Lee, Jeong Hyun, West, Anthony P., Chen, Courtney, Gao, Han, Gnanapragasam, Priyanthi N.P., Mares, René, Seaman, Michael S., Ward, Andrew B., Nussenzweig, Michel C., Bjorkman, Pamela J.

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Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies von McGuire, Andrew T, Hoot, Sam, Dreyer, Anita M, Lippy, Adriana, Stuart, Andrew, Cohen, Kristen W, Jardine, Joseph, Menis, Sergey, Scheid, Johannes F, West, Anthony P, Schief, William R, Stamatatos, Leonidas

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B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV von Scheid, Johannes F., Barnes, Christopher O., Eraslan, Basak, Hudak, Andrew, Keeffe, Jennifer R., Cosimi, Lisa A., Brown, Eric M., Muecksch, Frauke, Weisblum, Yiska, Zhang, Shuting, Delorey, Toni, Woolley, Ann E., Ghantous, Fadi, Park, Sung-Moo, Phillips, Devan, Tusi, Betsabeh, Huey-Tubman, Kathryn E., Cohen, Alexander A., Gnanapragasam, Priyanthi N.P., Rzasa, Kara, Hatziioanno, Theodora, Durney, Michael A., Gu, Xiebin, Tada, Takuya, Landau, Nathaniel R., West, Anthony P., Rozenblatt-Rosen, Orit, Seaman, Michael S., Baden, Lindsey R., Graham, Daniel B., Deguine, Jacques, Bieniasz, Paul D., Regev, Aviv, Hung, Deborah, Bjorkman, Pamela J., Xavier, Ramnik J.

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HIV therapy by a combination of broadly neutralizing antibodies in humanized mice von Klein, Florian, Halper-Stromberg, Ariel, Horwitz, Joshua A., Gruell, Henning, Scheid, Johannes F., Bournazos, Stylianos, Mouquet, Hugo, Spatz, Linda A., Diskin, Ron, Abadir, Alexander, Zang, Trinity, Dorner, Marcus, Billerbeck, Eva, Labitt, Rachael N., Gaebler, Christian, Marcovecchio, Paola M., Incesu, Reha-Baris, Eisenreich, Thomas R., Bieniasz, Paul D., Seaman, Michael S., Bjorkman, Pamela J., Ravetch, Jeffrey V., Ploss, Alexander, Nussenzweig, Michel C.

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A robust pipeline for rapid production of versatile nanobody repertoires von Fridy, Peter C, Li, Yinyin, Keegan, Sarah, Thompson, Mary K, Nudelman, Ilona, Scheid, Johannes F, Oeffinger, Marlene, Nussenzweig, Michel C, Fenyö, David, Chait, Brian T, Rout, Michael P

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Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117 von Caskey, Marina, Klein, Florian, Lorenzi, Julio C. C., Seaman, Michael S., West, Anthony P., Buckley, Noreen, Kremer, Gisela, Nogueira, Lilian, Braunschweig, Malte, Scheid, Johannes F., Horwitz, Joshua A., Shimeliovich, Irina, Ben-Avraham, Sivan, Witmer-Pack, Maggi, Platten, Martin, Lehmann, Clara, Burke, Leah A., Hawthorne, Thomas, Gorelick, Robert J., Walker, Bruce D., Keler, Tibor, Gulick, Roy M., Fätkenheuer, Gerd, Schlesinger, Sarah J., Nussenzweig, Michel C.

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Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design von Diskin, Ron, Scheid, Johannes F., Marcovecchio, Paola M., West, Anthony P., Klein, Florian, Gao, Han, Gnanapragasam, Priyanthi N. P., Abadir, Alexander, Seaman, Michael S., Nussenzweig, Michel C., Bjorkman, Pamela J.

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Prolonged viral suppression with anti-HIV-1 antibody therapy von Gaebler, Christian, Nogueira, Lilian, Stoffel, Elina, Oliveira, Thiago Y., Breton, Gaëlle, Millard, Katrina G., Turroja, Martina, Butler, Allison, Ramos, Victor, Seaman, Michael S., Reeves, Jacqueline D., Petroupoulos, Christos J., Shimeliovich, Irina, Gazumyan, Anna, Jiang, Caroline S., Jilg, Nikolaus, Scheid, Johannes F., Gandhi, Rajesh, Walker, Bruce D., Sneller, Michael C., Fauci, Anthony, Chun, Tae-Wook, Caskey, Marina, Nussenzweig, Michel C.

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Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies von McGuire, Andrew T., Dreyer, Anita M., Carbonetti, Sara, Lippy, Adriana, Glenn, Jolene, Scheid, Johannes F., Mouquet, Hugo, Stamatatos, Leonidas

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Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals von Nussenzweig, Michel C, Scheid, Johannes F, Mouquet, Hugo, Feldhahn, Niklas, Seaman, Michael S, Velinzon, Klara, Pietzsch, John, Ott, Rene G, Anthony, Robert M, Zebroski, Henry, Hurley, Arlene, Phogat, Adhuna, Chakrabarti, Bimal, Li, Yuxing, Connors, Mark, Pereyra, Florencia, Walker, Bruce D, Wardemann, Hedda, Ho, David, Wyatt, Richard T, Mascola, John R, Ravetch, Jeffrey V

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Non-neutralizing Antibodies Alter the Course of HIV-1 Infection In Vivo von Horwitz, Joshua A., Bar-On, Yotam, Lu, Ching-Lan, Fera, Daniela, Lockhart, Ainsley A.K., Lorenzi, Julio C.C., Nogueira, Lilian, Golijanin, Jovana, Scheid, Johannes F., Seaman, Michael S., Gazumyan, Anna, Zolla-Pazner, Susan, Nussenzweig, Michel C.

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Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses von Mouquet, Hugo, Klein, Florian, Scheid, Johannes F, Warncke, Malte, Pietzsch, John, Oliveira, Thiago Y K, Velinzon, Klara, Seaman, Michael S, Nussenzweig, Michel C

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Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission von Malbec, Marine, Porrot, Françoise, Rua, Rejane, Horwitz, Joshua, Klein, Florian, Halper-Stromberg, Ari, Scheid, Johannes F, Eden, Caroline, Mouquet, Hugo, Nussenzweig, Michel C, Schwartz, Olivier

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