Overlapping genetic architecture between Parkinson disease and melanoma von Dube, Umber, Ibanez, Laura, Budde, John P., Benitez, Bruno A., Davis, Albert A., Harari, Oscar, Iles, Mark M., Law, Matthew H., Brown, Kevin M., Cruchaga, Carlos

Volltext

Correction to: Overlapping genetic architecture between Parkinson disease and melanoma von Dube, Umber, Ibanez, Laura, Budde, John P., Benitez, Bruno A., Davis, Albert A., Harari, Oscar, Iles, Mark M., Law, Matthew H., Brown, Kevin M., Cruchaga, Carlos

Volltext

Overlapping genetic architecture between Parkinson disease and melanoma von Dube, U., Budde, J.P., Benitez, B.A., Davis, A.A., Harari, O., Iles, M.M., Brown, K.M., Agee, M., Alipanahi, B., Auton, A., Bell, R.K., Bryc, K., Elson, S.L., Fontanillas, P., Furlotte, N.A., Hinds, D.A., Kleinman, A., Litterman, N.K., McCreight, J.C., McIntyre, M.H., Mountain, J.L., Noblin, E.S., Northover, C.A.M., Sathirapongsasuti, J.F., Sazonova, O.V., Shelton, J.F., Tian, C., Tung, J.C.Y., Vacic, V., Wilson, C.H., Bishop, D.T., Brossard, M., Martin, N.G., Moses, E.K., Song, F., Barrett, J.H., Kumar, R., Easton, D.F., Pharoah, P.D., Swerdlow, A.J., Kypreou, K.P., Taylor, J.C., Harland, M., Randerson-Moor, J., Akslen, L.A., Andresen, P.A., Avril, M.F., Azizi, E., Scarra, G.B., Debniak, T., Duffy, D.L., Elder, D.E., Fang, S., Friedman, E., Galan, P., Gillanders, E.M., Goldstein, A.M., Gruis, N.A., Hansson, J., Helsing, P., Hocevar, M., Ingvar, C., Kanetsky, P.A., Chen, W.V., Landi, M.T., Lang, J., Lathrop, G.M., Lubinski, J., Mackie, R.M., Mann, G.J., Molven, A., Montgomery, G.W., Novakovic, S., Olsson, H., Puig, S., Puig-Butille, J.A., Wu, W., Qureshi, A.A., Radford-Smith, G.L., Stoep, N. van der, Doorn, R. van, Whiteman, D.C., Craig, J.E., Schadendorf, E., Burdon, K.P., Nyholt, D.R., Pooley, K.A., Orr, N., Stratigos, A.J., Cust, A.E., Ward, S.V., Hayward, N.K., Han, J., Schulze, H.J., Dunning, A.M., Bishop, J.A., Demenais, F., Amos, C.I., MacGregor, S., Cruchaga, C.

Volltext bestellen

Combined BRAF and MEK Inhibition versus BRAF Inhibition Alone in Melanoma von Long, Georgina V, Stroyakovskiy, Daniil, Gogas, Helen, Levchenko, Evgeny, de Braud, Filippo, Larkin, James, Garbe, Claus, Jouary, Thomas, Hauschild, Axel, Grob, Jean Jacques, Chiarion Sileni, Vanna, Lebbe, Celeste, Mandalà, Mario, Millward, Michael, Arance, Ana, Bondarenko, Igor, Haanen, John B.A.G, Hansson, Johan, Utikal, Jochen, Ferraresi, Virginia, Kovalenko, Nadezhda, Mohr, Peter, Probachai, Volodymyr, Schadendorf, Dirk, Nathan, Paul, Robert, Caroline, Ribas, Antoni, DeMarini, Douglas J, Irani, Jhangir G, Casey, Michelle, Ouellet, Daniele, Martin, Anne-Marie, Le, Ngocdiep, Patel, Kiran, Flaherty, Keith

Volltext

Immunotherapy in melanoma: Recent advances and future directions von Franklin, C, Livingstone, E, Roesch, A, Schilling, B, Schadendorf, D

Volltext

Five-Year Analysis of Adjuvant Dabrafenib plus Trametinib in Stage III Melanoma von Dummer, Reinhard, Hauschild, Axel, Santinami, Mario, Atkinson, Victoria, Mandalà, Mario, Kirkwood, John M, Chiarion Sileni, Vanna, Larkin, James, Nyakas, Marta, Dutriaux, Caroline, Haydon, Andrew, Robert, Caroline, Mortier, Laurent, Schachter, Jacob, Lesimple, Thierry, Plummer, Ruth, Dasgupta, Kohinoor, Gasal, Eduard, Tan, Monique, Long, Georgina V, Schadendorf, Dirk

Volltext

EANO–ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with brain metastasis from solid tumours von Le Rhun, E., Guckenberger, M., Smits, M., Dummer, R., Bachelot, T., Sahm, F., Galldiks, N., de Azambuja, E., Berghoff, A.S., Metellus, P., Peters, S., Hong, Y.-K., Winkler, F., Schadendorf, D., van den Bent, M., Seoane, J., Stahel, R., Minniti, G., Wesseling, P., Weller, M., Preusser, M.

Volltext

Relatlimab and Nivolumab versus Nivolumab in Untreated Advanced Melanoma von Tawbi, Hussein A, Schadendorf, Dirk, Lipson, Evan J, Ascierto, Paolo A, Matamala, Luis, Castillo Gutiérrez, Erika, Rutkowski, Piotr, Gogas, Helen J, Lao, Christopher D, De Menezes, Juliana Janoski, Dalle, Stéphane, Arance, Ana, Grob, Jean-Jacques, Srivastava, Shivani, Abaskharoun, Mena, Hamilton, Melissa, Keidel, Sarah, Simonsen, Katy L, Sobiesk, Anne Marie, Li, Bin, Hodi, F. Stephen, Long, Georgina V

Volltext

Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma von Robert, Caroline, Grob, Jean J, Stroyakovskiy, Daniil, Karaszewska, Boguslawa, Hauschild, Axel, Levchenko, Evgeny, Chiarion Sileni, Vanna, Schachter, Jacob, Garbe, Claus, Bondarenko, Igor, Gogas, Helen, Mandalá, Mario, Haanen, John B.A.G, Lebbé, Celeste, Mackiewicz, Andrzej, Rutkowski, Piotr, Nathan, Paul D, Ribas, Antoni, Davies, Michael A, Flaherty, Keith T, Burgess, Paul, Tan, Monique, Gasal, Eduard, Voi, Maurizio, Schadendorf, Dirk, Long, Georgina V

Volltext

Neoadjuvant Cemiplimab for Stage II to IV Cutaneous Squamous-Cell Carcinoma von Gross, Neil D., Miller, David M., Khushalani, Nikhil I., Divi, Vasu, Ruiz, Emily S., Lipson, Evan J., Meier, Friedegund, Su, Yungpo B., Swiecicki, Paul L., Atlas, Jennifer, Geiger, Jessica L., Hauschild, Axel, Choe, Jennifer H., Hughes, Brett G.M., Schadendorf, Dirk, Patel, Vishal A., Homsi, Jade, Taube, Janis M., Lim, Annette M., Ferrarotto, Renata, Kaufman, Howard L., Seebach, Frank, Lowy, Israel, Yoo, Suk-Young, Mathias, Melissa, Fenech, Keilah, Han, Hyunsil, Fury, Matthew G., Rischin, Danny

Volltext

Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: long-term survival and safety analysis of a phase 3 study von Long, G.V., Flaherty, K.T., Stroyakovskiy, D., Gogas, H., Levchenko, E., de Braud, F., Larkin, J., Garbe, C., Jouary, T., Hauschild, A., Chiarion-Sileni, V., Lebbe, C., Mandalà, M., Millward, M., Arance, A., Bondarenko, I., Haanen, J.B.A.G., Hansson, J., Utikal, J., Ferraresi, V., Mohr, P., Probachai, V., Schadendorf, D., Nathan, P., Robert, C., Ribas, A., Davies, M.A., Lane, S.R., Legos, J.J., Mookerjee, B., Grob, J.-J.

Volltext

A Landscape of Driver Mutations in Melanoma von Hodis, Eran, Watson, Ian R., Kryukov, Gregory V., Arold, Stefan T., Imielinski, Marcin, Theurillat, Jean-Philippe, Nickerson, Elizabeth, Auclair, Daniel, Li, Liren, Place, Chelsea, DiCara, Daniel, Ramos, Alex H., Lawrence, Michael S., Cibulskis, Kristian, Sivachenko, Andrey, Voet, Douglas, Saksena, Gordon, Stransky, Nicolas, Onofrio, Robert C., Winckler, Wendy, Ardlie, Kristin, Wagle, Nikhil, Wargo, Jennifer, Chong, Kelly, Morton, Donald L., Stemke-Hale, Katherine, Chen, Guo, Noble, Michael, Meyerson, Matthew, Ladbury, John E., Davies, Michael A., Gershenwald, Jeffrey E., Wagner, Stephan N., Hoon, Dave S.B., Schadendorf, Dirk, Lander, Eric S., Gabriel, Stacey B., Getz, Gad, Garraway, Levi A., Chin, Lynda

Volltext

Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma von Flaherty, Keith T, Robert, Caroline, Hersey, Peter, Nathan, Paul, Garbe, Claus, Milhem, Mohammed, Demidov, Lev V, Hassel, Jessica C, Rutkowski, Piotr, Mohr, Peter, Dummer, Reinhard, Trefzer, Uwe, Larkin, James M.G, Utikal, Jochen, Dreno, Brigitte, Nyakas, Marta, Middleton, Mark R, Becker, Jürgen C, Casey, Michelle, Sherman, Laurie J, Wu, Frank S, Ouellet, Daniele, Martin, Anne-Marie, Patel, Kiran, Schadendorf, Dirk

Volltext

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation von Chapman, Paul B, Hauschild, Axel, Robert, Caroline, Haanen, John B, Ascierto, Paolo, Larkin, James, Dummer, Reinhard, Garbe, Claus, Testori, Alessandro, Maio, Michele, Hogg, David, Lorigan, Paul, Lebbe, Celeste, Jouary, Thomas, Schadendorf, Dirk, Ribas, Antoni, O'Day, Steven J, Sosman, Jeffrey A, Kirkwood, John M, Eggermont, Alexander M.M, Dreno, Brigitte, Nolop, Keith, Li, Jiang, Nelson, Betty, Hou, Jeannie, Lee, Richard J, Flaherty, Keith T, McArthur, and Grant A

Volltext

Drug-induced sarcoidosis-like reaction in adjuvant immunotherapy: Increased rate and mimicker of metastasis von Chorti, Eleftheria, Kanaki, Theodora, Zimmer, Lisa, Hadaschik, Eva, Ugurel, Selma, Gratsias, Emmanouil, Roesch, Alexander, Bonella, Francesco, Wessendorf, Thomas E., Wälscher, Julia, Theegarten, Dirk, Schadendorf, Dirk, Livingstone, Elisabeth

Volltext

Elevated baseline serum PD-1 or PD-L1 predicts poor outcome of PD-1 inhibition therapy in metastatic melanoma von Ugurel, S., Schadendorf, D., Horny, K., Sucker, A., Schramm, S., Utikal, J., Pföhler, C., Herbst, R., Schilling, B., Blank, C., Becker, J.C., Paschen, A., Zimmer, L., Livingstone, E., Horn, P.A., Rebmann, V.

Volltext

A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition von Whittaker, Steven R, Theurillat, Jean-Philippe, Van Allen, Eliezer, Wagle, Nikhil, Hsiao, Jessica, Cowley, Glenn S, Schadendorf, Dirk, Root, David E, Garraway, Levi A

Volltext

Treatment in metastatic melanoma—time to re-think von Schadendorf, D., Livingstone, E., Zimmer, L.

Volltext

RAS Mutations Are Associated With the Development of Cutaneous Squamous Cell Tumors in Patients Treated With RAF Inhibitors von OBERHOLZER, Patrick A, KEE, Damien, PIRIS, Adriano, MACCONAILL, Laura E, ROBERT, Caroline, HOFBAUER, Günther F. L, MCARTHUR, Grant A, SCHADENDORF, Dirk, GARRAWAY, Levi A, DZIUNYCZ, Piotr, SUCKER, Antje, KAMSUKOM, Nyam, JONES, Robert, RODEN, Christine, CHALK, Clinton J, ARDLIE, Kristin, PALESCANDOLO, Emanuele

Volltext

NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo von Lakshmikanth, Tadepally, Burke, Shannon, Ali, Talib Hassan, Kimpfler, Silvia, Ursini, Francesco, Ruggeri, Loredana, Capanni, Marusca, Umansky, Viktor, Paschen, Annette, Sucker, Antje, Pende, Daniela, Groh, Veronika, Biassoni, Roberto, Höglund, Petter, Kato, Masashi, Shibuya, Kazuko, Schadendorf, Dirk, Anichini, Andrea, Ferrone, Soldano, Velardi, Andrea, Kärre, Klas, Shibuya, Akira, Carbone, Ennio, Colucci, Francesco

Volltext