Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages von Rosenbluth, Jennifer M., Schackmann, Ron C. J., Gray, G. Kenneth, Selfors, Laura M., Li, Carman Man-Chung, Boedicker, Mackenzie, Kuiken, Hendrik J., Richardson, Andrea, Brock, Jane, Garber, Judy, Dillon, Deborah, Sachs, Norman, Clevers, Hans, Brugge, Joan S.

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A peripheral immune signature of responsiveness to PD-1 blockade in patients with classical Hodgkin lymphoma von Cader, Fathima Zumla, Hu, Xihao, Goh, Walter L., Wienand, Kirsty, Ouyang, Jing, Mandato, Elisa, Redd, Robert, Lawton, Lee N., Chen, Pei-Hsuan, Weirather, Jason L., Schackmann, Ron C. J., Li, Bo, Ma, Wenjiang, Armand, Philippe, Rodig, Scott J., Neuberg, Donna, Liu, X. Shirley, Shipp, Margaret A.

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Rapid Sequential in Situ Multiplexing with DNA Exchange Imaging in Neuronal Cells and Tissues von Wang, Yu, Woehrstein, Johannes B, Donoghue, Noah, Dai, Mingjie, Avendaño, Maier S, Schackmann, Ron C. J, Zoeller, Jason J, Wang, Shan Shan H, Tillberg, Paul W, Park, Demian, Lapan, Sylvain W, Boyden, Edward S, Brugge, Joan S, Kaeser, Pascal S, Church, George M, Agasti, Sarit S, Jungmann, Ralf, Yin, Peng

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Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP von Bui, Duyen Amy, Lee, Wendy, White, Anne E, Harper, J Wade, Schackmann, Ron C J, Overholtzer, Michael, Selfors, Laura M, Brugge, Joan S

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Clonal populations of a human TNBC model display significant functional heterogeneity and divergent growth dynamics in distinct contexts von Kuiken, Hendrik J., Dhakal, Sabin, Selfors, Laura M., Friend, Chandler M., Zhang, Tian, Callari, Maurizio, Schackmann, Ron C. J., Gray, G. Kenneth, Crowdis, Jett, Bhang, Hyo-eun C., Baslan, Timour, Stegmeier, Frank, Gygi, Steven P., Caldas, Carlos, Brugge, Joan S.

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p120-catenin in cancer - mechanisms, models and opportunities for intervention von Schackmann, Ron C J, Tenhagen, Milou, van de Ven, Robert A H, Derksen, Patrick W B

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Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling von SCHACKMANN, Ron C. J, KLARENBEEK, Sjoerd, VAN DER WALL, Elsken, VAN DIEST, Paul J, JONKERS, Jos, DERKSEN, Patrick W. B, VLUG, Eva J, STELLOO, Suzan, VAN AMERSFOORT, Miranda, TENHAGEN, Milou, BRAUMULLER, Tanya M, VERMEULEN, Jeroen F, VAN DER GROEP, Petra, PEETERS, Ton

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Mass cytometry of Hodgkin lymphoma reveals a CD4+ regulatory T-cell–rich and exhausted T-effector microenvironment von Cader, Fathima Zumla, Schackmann, Ron C.J., Hu, Xihao, Wienand, Kirsty, Redd, Robert, Chapuy, Bjoern, Ouyang, Jing, Paul, Nicole, Gjini, Evisa, Lipschitz, Mikel, Armand, Philippe, Wu, David, Fromm, Jonathan R., Neuberg, Donna, Liu, X. Shirley, Rodig, Scott J., Shipp, Margaret A.

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Zenocutuzumab, a HER2xHER3 Bispecific Antibody, Is Effective Therapy for Tumors Driven by NRG1 Gene Rearrangements von Schram, Alison M, Odintsov, Igor, Espinosa-Cotton, Madelyn, Khodos, Inna, Sisso, Whitney J, Mattar, Marissa S, Lui, Allan J W, Vojnic, Morana, Shameem, Sara H, Chauhan, Thrusha, Torrisi, Jean, Ford, Jim, O'Connor, Marie N, Geuijen, Cecile A W, Schackmann, Ron C J, Lammerts van Bueren, Jeroen J, Wasserman, Ernesto, de Stanchina, Elisa, O'Reilly, Eileen M, Ladanyi, Marc, Drilon, Alexander, Somwar, Romel

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Nuclear p120-catenin regulates the anoikis resistance of mouse lobular breast cancer cells through Kaiso-dependent Wnt11 expression von van de Ven, Robert A H, Tenhagen, Milou, Meuleman, Wouter, van Riel, Jeske J G, Schackmann, Ron C J, Derksen, Patrick W B

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A human breast atlas integrating single-cell proteomics and transcriptomics von Gray, G. Kenneth, Li, Carman Man-Chung, Rosenbluth, Jennifer M., Selfors, Laura M., Girnius, Nomeda, Lin, Jia-Ren, Schackmann, Ron C.J., Goh, Walter L., Moore, Kaitlin, Shapiro, Hana K., Mei, Shaolin, D’Andrea, Kurt, Nathanson, Katherine L., Sorger, Peter K., Santagata, Sandro, Regev, Aviv, Garber, Judy E., Dillon, Deborah A., Brugge, Joan S.

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Cytosolic p120-catenin regulates growth of metastatic lobular carcinoma through Rock1-mediated anoikis resistance von Schackmann, Ron C J, van Amersfoort, Miranda, Haarhuis, Judith H I, Vlug, Eva J, Halim, Vincentius A, Roodhart, Jeanine M L, Vermaat, Joost S, Voest, Emile E, van der Groep, Petra, van Diest, Paul J, Jonkers, Jos, Derksen, Patrick W B

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Oncogenic K-Ras Turns Death Receptors Into Metastasis-Promoting Receptors in Human and Mouse Colorectal Cancer Cells von Hoogwater, Frederik J.H, Nijkamp, Maarten W, Smakman, Niels, Steller, Ernst J.A, Emmink, Benjamin L, Westendorp, B. Florien, Raats, Danielle A.E, Sprick, Martin R, Schaefer, Uta, Van Houdt, Winan J, De Bruijn, Menno T, Schackmann, Ron C.J, Derksen, Patrick W.B, Medema, Jan–Paul, Walczak, Henning, Borel Rinkes, Inne H.M, Kranenburg, Onno

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Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages von Rosenbluth, Jennifer M, Schackmann, Ron C J, Gray, G Kenneth, Selfors, Laura M, Li, Carman Man-Chung, Boedicker, Mackenzie, Kuiken, Hendrik J, Richardson, Andrea, Brock, Jane, Garber, Judy, Dillon, Deborah, Sachs, Norman, Clevers, Hans, Brugge, Joan S

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A Peripheral Immune Signature of Responsiveness to PD-1 Blockade in Patients With Classical Hodgkin Lymphoma von Cader, Fathima Zumla, Hu, Xihao, Goh, Walter L, Wienand, Kirsty, Ouyang, Jing, Mandato, Elisa, Redd, Robert, Lawton, Lee, Chen, Pei-Hsuan, Weirather, Jason L, Schackmann, Ron C. J, Li, Bo, Ma, Wenjiang, Armand, Philippe, Rodig, Scott, Neuberg, Donna, Liu, X. Shirley, Shipp, Margaret A, shipp

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Abstract PD7-03: A living biobank of normal mammary organoids derived from patients at low and increased risk of developing breast cancer von Rosenbluth, Jennifer M, Li, Carman Man-Chung, Gray, Kenneth G, Gao, Walter, Schackmann, Ron CJ, Zoeller, Jason J, Selfors, Laura M, Moore, Kaitlin, Dillon, Deborah, Garber, Judy, Brugge, Joan S

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Nuclear p120-catenin regulates the anoikis resistance of mouse lobular breast cancer cells through Kaiso-dependent Wnt11 expression von van de Ven, Robert A H, Tenhagen, Milou, Meuleman, Wouter, van Riel, Jeske J G, Schackmann, Ron C J, Derksen, Patrick W B

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Nuclear p120-catenin contributes to anoikis resistance of Lobular Breast Cancer through Kaiso-dependent Wnt11 expression von van de Ven, Robert A. H., Tenhagen, Milou, Meuleman, Wouter, van Riel, Jeske J. G., Schackmann, Ron C. J., Derksen, Patrick W. B.

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Abstract A059: Context-dependent regulation of breast cancer metastasis by E-cadherin and p120-catenin von Schackmann, Ron CJ, Klarenbeek, Sjoerd, Amersfoort, Miranda van, Jonkers, Jos, Diest, Paul van, Derksen, Patrick

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Abstract 956: The HER2×HER3 bi-specific antibody Zenocutuzumab is effective at blocking growth of tumors driven by NRG1 gene fusions von Odintsov, Igor, Khodos, Inna, Espinosa-Cotton, Madelyn, Lui, Allan J., Mattar, Marissa, Schram, Alison M., Schackmann, Ron C., van Bueren, Jeroen Lammerts, Geuijen, Cecile A., de Stanchina, Elisa, Ladanyi, Marc, Somwar, Romel

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