Caloric restriction reverses the deficits in leptin receptor protein and leptin signaling capacity associated with diet-induced obesity: role of leptin in the regulation of hypotha... von Wilsey, J, Scarpace, PJ

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Leptin increases uncoupling protein expression and energy expenditure von Scarpace, P. J, Matheny, M, Pollock, B. H, Tumer, N

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Hypothalamic leptin resistance is associated with impaired leptin signal transduction in aged obese rats von Scarpace, P.J, Matheny, M, Tümer, N

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Simultaneous introduction of a novel high fat diet and wheel running induces anorexia von Scarpace, E.T, Matheny, M, Strehler, K.Y.E, Shapiro, A, Cheng, K.Y, Tümer, N, Scarpace, P.J

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Leptin antagonist reveals that the normalization of caloric intake and the thermic effect of food after high-fat feeding are leptin dependent von Zhang, J, Matheny, M. K, Tumer, N, Mitchell, M. K, Scarpace, P. J

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Leptin resistance exacerbates diet-induced obesity and is associated with diminished maximal leptin signalling capacity in rats von SCARPACE, P. J, MATHENY, M, TÜMER, N, CHENG, K. Y, ZHANG, Y

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Induction of uncoupling protein 1 by central interleukin-6 gene delivery is dependent on sympathetic innervation of brown adipose tissue and underlies one mechanism of body weight... von Li, G, Klein, R.L, Matheny, M, King, M.A, Meyer, E.M, Scarpace, P.J

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Hypothalamic pro-opiomelanocortin gene delivery ameliorates obesity and glucose intolerance in aged rats von LI, G, ZHANG, Y, WILSEY, J. T, SCARPACE, P. J

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Responses to the cannabinoid receptor-1 antagonist, AM251, are more robust with age and with high-fat feeding von Judge, M K, Zhang, Y, Scarpace, P J

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Unabated anorexic and enhanced thermogenic responses to melanotan II in diet-induced obese rats despite reduced melanocortin 3 and 4 receptor expression von Li, G, Zhang, Y, Wilsey, JT, Scarpace, PJ

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Mechanism for obesity-induced increase in myocardial lipid peroxidation von VINCENT, H. K, POWERS, S. K, DIRKS, A. J, SCARPACE, P. J

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Wheel running eliminates high-fat preference and enhances leptin signaling in the ventral tegmental area von Scarpace, P.J, Matheny, M, Zhang, Y

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Prolonged hyperphagia with high-fat feeding contributes to exacerbated weight gain in rats with adult-onset obesity von Judge, M. K, Zhang, J, Tumer, N, Carter, C, Daniels, M. J, Scarpace, P. J

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UCP2, UCP3 and leptin gene expression: modulation by food restriction and leptin von Scarpace, PJ, Nicolson, M, Matheny, M

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Impaired leptin responsiveness in aged rats von Scarpace, P J, Matheny, M, Moore, R L, Tümer, N

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Region-specific diet-induced and leptin-induced cellular leptin resistance includes the ventral tegmental area in rats von Matheny, M., Shapiro, A., Tümer, N., Scarpace, P.J.

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Central leptin gene therapy suppresses body weight gain, adiposity and serum insulin without affecting food consumption in normal rats: a long-term study von Dhillon, H, Kalra, S.P, Prima, V, Zolotukhin, S, Scarpace, P.J, Moldawer, L.L, Muzyczka, N, Kalra, P.S

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Lean rats with hypothalamic pro-opiomelanocortin overexpression exhibit greater diet-induced obesity and impaired central melanocortin responsiveness von Li, G, Zhang, Y, Cheng, K. Y, Scarpace, P. J

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Differential physiological responses to central leptin overexpression in male and female rats von Côté, I., Green, S. M., Toklu, H. Z., Morgan, D., Carter, C. S., Tümer, N., Scarpace, P. J.

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Central leptin gene delivery evokes persistent leptin signal transduction in young and aged-obese rats but physiological responses become attenuated over time in aged-obese rats von Scarpace, P.J., Matheny, M., Zhang, Y., Tümer, N., Frase, C.D., Shek, E.W., Hong, B., Prima, V., Zolotukhin, S.

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