The HZB F2X‐Facility—An Efficient Crystallographic Fragment Screening Platform von Barthel, Tatjana, Benz, Laila, Basler, Yara, Crosskey, Thomas, Dillmann, Alexander, Förster, Ronald, Fröling, Paula, Dieguez, Camilla G., Gless, Christine, Hauß, Thomas, Hellmig, Michael, Jänisch, Lea, James, David, Lennartz, Frank, Mijatovic, Jelena, Oelker, Melanie, Scanlan, James W., Weber, Gert, Wollenhaupt, Jan, Mueller, Uwe, Dobbek, Holger, Wahl, Markus C., Weiss, Manfred S.

Volltext

Cover Image: Volume 3 Issue 6 von Barthel, Tatjana, Benz, Laila, Basler, Yara, Crosskey, Thomas, Dillmann, Alexander, Förster, Ronald, Fröling, Paula, Dieguez, Camilla G., Gless, Christine, Hauß, Thomas, Hellmig, Michael, Jänisch, Lea, James, David, Lennartz, Frank, Mijatovic, Jelena, Oelker, Melanie, Scanlan, James W., Weber, Gert, Wollenhaupt, Jan, Mueller, Uwe, Dobbek, Holger, Wahl, Markus C., Weiss, Manfred S.

Volltext

A microarray for assessing transcription from pelagic marine microbial taxa von Shilova, Irina N, Robidart, Julie C, James Tripp, H, Turk-Kubo, Kendra, Wawrik, Boris, Post, Anton F, Thompson, Anne W, Ward, Bess, Hollibaugh, James T, Millard, Andy, Ostrowski, Martin, J Scanlan, David, Paerl, Ryan W, Stuart, Rhona, Zehr, Jonathan P

Volltext

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield von Pejchal, Robert, Doores, Katie J., Walker, Laura M., Khayat, Reza, Huang, Po-Ssu, Wang, Sheng-Kai, Stanfield, Robyn L., Julien, Jean-Philippe, Ramos, Alejandra, Crispin, Max, Depetris, Rafael, Katpally, Umesh, Marozsan, Andre, Cupo, Albert, Maloveste, Sebastien, Liu, Yan, McBride, Ryan, Ito, Yukishige, Sanders, Rogier W., Ogohara, Cassandra, Paulson, James C., Feizi, Ten, Scanlan, Christopher N., Wong, Chi-Huey, Moore, John P., Olson, William C., Ward, Andrew B., Poignard, Pascal, Schief, William R., Burton, Dennis R., Wilson, Ian A.

Volltext

Large‐scale deep proteomic analysis in Alzheimer's disease brain regions across race and ethnicity von Seifar, Fatemeh, Fox, Edward J., Shantaraman, Anantharaman, Liu, Yue, Dammer, Eric B., Modeste, Erica, Duong, Duc M., Yin, Luming, Trautwig, Adam N., Guo, Qi, Xu, Kaiming, Ping, Lingyan, Reddy, Joseph S., Allen, Mariet, Quicksall, Zachary, Heath, Laura, Scanlan, Jo, Wang, Erming, Wang, Minghui, Linden, Abby Vander, Poehlman, William, Chen, Xianfeng, Baheti, Saurabh, Ho, Charlotte, Nguyen, Thuy, Yepez, Geovanna, Mitchell, Adriana O., Oatman, Stephanie R., Wang, Xue, Carrasquillo, Minerva M., Runnels, Alexi, Beach, Thomas, Serrano, Geidy E., Dickson, Dennis W., Lee, Edward B., Golde, Todd E., Prokop, Stefan, Barnes, Lisa L., Zhang, Bin, Haroutunian, Varham, Gearing, Marla, Lah, James. J, De Jager, Philip, Bennett, David A, Greenwood, Anna, Ertekin‐Taner, Nilüfer, Levey, Allan I., Wingo, Aliza, Wingo, Thomas, Seyfried, Nicholas T.

Volltext

A Multifaceted Intervention for Patients With Anaphylaxis Increases Epinephrine Use in Adult Emergency Department von Manivannan, Veena, MBBS, Hess, Erik P., MD, MSc, Bellamkonda, Venkatesh R., MD, Nestler, David M., MD, Bellolio, M. Fernanda, MD, MS, Hagan, John B., MD, Sunga, Kharmene L., MD, Decker, Wyatt W., MD, Li, James T.C., MD, PhD, Scanlan-Hanson, Lori N., RN, MS, Vukov, Samuel C., BS, Campbell, Ronna L., MD, PhD

Volltext

Brief Screening Tests for Dementia von Lorentz, Wendy J, Scanlan, James M, Borson, Soo

Volltext

Making thawed universal donor plasma available rapidly for massively bleeding trauma patients: experience from the Pragmatic, Randomized Optimal Platelets and Plasma Ratios (PROPPR... von Novak, Deborah J., Bai, Yu, Cooke, Rhonda K., Marques, Marisa B., Fontaine, Magali J., Gottschall, Jerome L., Carey, Patricia M., Scanlan, Richard M., Fiebig, Eberhard W., Shulman, Ira A., Nelson, Janice M., Flax, Sherri, Duncan, Veda, Daniel-Johnson, Jennifer A., Callum, Jeannie L., Holcomb, John B., Fox, Erin E., Baraniuk, Sarah, Tilley, Barbara C., Schreiber, Martin A., Inaba, Kenji, Rizoli, Sandro, Podbielski, Jeanette M., Cotton, Bryan A., Hess, John R.

Volltext

Depressed Mood Mediates Decline in Cognitive Processing Speed in Caregivers von Vitaliano, Peter P., Zhang, Jianping, Young, Heather M., Caswell, Lisa W., Scanlan, James M., Echeverria, Diana

Volltext

Bridging the gap: Multi‐omics profiling of brain tissue in Alzheimer's disease and older controls in multi‐ethnic populations von Reddy, Joseph S., Heath, Laura, Linden, Abby Vander, Allen, Mariet, Lopes, Katia de Paiva, Seifar, Fatemeh, Wang, Erming, Ma, Yiyi, Poehlman, William L., Quicksall, Zachary S., Runnels, Alexi, Wang, Yanling, Duong, Duc M., Yin, Luming, Xu, Kaiming, Modeste, Erica S., Shantaraman, Anantharaman, Dammer, Eric B., Ping, Lingyan, Oatman, Stephanie R., Scanlan, Jo, Ho, Charlotte, Carrasquillo, Minerva M., Atik, Merve, Yepez, Geovanna, Mitchell, Adriana O., Nguyen, Thuy T., Chen, Xianfeng, Marquez, David X., Reddy, Hasini, Xiao, Harrison, Seshadri, Sudha, Mayeux, Richard, Prokop, Stefan, Lee, Edward B., Serrano, Geidy E., Beach, Thomas G., Teich, Andrew F., Haroutunian, Varham, Fox, Edward J., Gearing, Marla, Wingo, Aliza, Wingo, Thomas, Lah, James J., Levey, Allan I., Dickson, Dennis W., Barnes, Lisa L., De Jager, Philip, Zhang, Bin, Bennett, David, Seyfried, Nicholas T., Greenwood, Anna K., Ertekin‐Taner, Nilüfer

Volltext

Older Blood Is Associated With Increased Mortality and Adverse Events in Massively Transfused Trauma Patients: Secondary Analysis of the PROPPR Trial von Jones, Allison R., Patel, Rakesh P., Marques, Marisa B., Donnelly, John P., Hess, John R., Wang, Henry E., Holcomb, John B., del Junco, Deborah J., Matijevic, Nena, Podbielski, Jeanette, Beeler, Angela M., Tilley, Barbara C., Baraniuk, Sarah, Zhu, Hongjian, Nixon, Joshua, Seay, Roann, Gonzalez, Michael O., Baer, Lisa, Wang, Yao-Wei W., Hula, Brittany S., Espino, Elena, Arora-Nutall, Kisha D., Sharma, Rishika, Cardenas, Jessica C., Rahbar, Elaheh, Burnett, Tyrone, Clark, David, May, Susanne, Leroux, Brian, Hoyt, David, Sheehan, Kellie, Arkin, Adam P., Hess, John R., Welch, Timothy, Pivalizza, Evan G., Gumbert, Sam D., Bai, Yu, Noland, Amy, Bulger, Eileen M., Klotz, Patricia, Warner, Keir J., Wilson, Angela, Boman, David, White, Nathan, Grabinsky, Andreas, Cohen, Mitchell J., Callcut, Rachael A., Nelson, Mary, Redick, Brittney, Conroy, Amanda, Fiebig, Eberhard, Mallari, Eireen, Muskat, Peter, Robinson, Bryce R.H., Branson, Richard D., Gomaa, Dina, Rodriguez, Carolina, Inaba, Kenji, Zhu, Jay G., Wong, Monica D., Henderson, Sean O., Nelson, Janice M., Matsushita, Cheryl Y., Scalea, Thomas M., Shaffer, Cynthia K., Herrera, Anthony V., Kallam, Seeta, Fontaine, Magali J., Cooke, Rhonda K., Fabian, Timothy C., Weinberg, Jordan A., Croce, Martin A., Wilson, Suzanne, Waddle-Smith, Lynda, Flax, Sherri, Brasel, Karen J., Walsh, Pamela, Nelson, Allia, Rokowski, Laurel L., Redford, Daniel T., Novak, Deborah J., Knoll, Susan, Kerby, Jeffrey D., Pittet, Jean-Francois, Bosarge, Patrick L., Williams, Carolyn R., Stephens, Shannon W., Wang, Henry E., Marques, Marisa B., Schreiber, Martin A., Watters, Jennifer M., Groat, Tahnee, Newgard, Craig, Miller, Beth, Rizoli, Sandro, Nascimento, Barto, Sobrian-Couroux, Skeeta, Reis, Marciano, Belo, Susan E., Merkley, Lisa

Volltext

Complete Genome Sequence of the Q-Fever Pathogen Coxiella burnetii von Seshadri, Rekha, Paulsen, Ian T., Eisen, Jonathan A., Read, Timothy D., Nelson, Karen E., Nelson, William C., Ward, Naomi L., Tettelin, Hervé, Davidsen, Tanja M., Beanan, Maureen J., Deboy, Robert T., Daugherty, Sean C., Brinkac, Lauren M., Madupu, Ramana, Dodson, Robert J., Khouri, Hoda M., Lee, Kathy H., Carty, Heather A., Scanlan, David, Heinzen, Robert A., Thompson, Herbert A., Samuel, James E., Fraser, Claire M., Heidelberg, John F.

Volltext

Clinical Benchmarks Regarding Multimodal Peripheral Nerve Blocks for Postoperative Analgesia: Observations Regarding Combined Perineural Midazolam‐Clonidine‐Buprenorphine‐Dexametha... von Williams, Brian A., Ibinson, James W., Mangione, Michael P., Scanlan, Rick L., Cohen, Peter Z.

Volltext

Hammett Analysis of Selective Thyroid Hormone Receptor Modulators Reveals Structural and Electronic Requirements for Hormone Antagonists von Nguyen, Ngoc-Ha, Apriletti, James W, Baxter, John D, Scanlan, Thomas S

Volltext

Hormone Selectivity in Thyroid Hormone Receptors von Wagner, Richard L, Huber, B. Russell, Shiau, Andrew K, Kelly, Alex, Cunha Lima, Suzana T, Scanlan, Thomas S, Apriletti, James W, Baxter, John D, West, Brian L, Fletterick, Robert J

Volltext

Selective modulation of thyroid hormone receptor action von Baxter, John D, Dillmann, Wolfgang H, West, Brian L, Huber, Russ, Furlow, J.David, Fletterick, Robert J, Webb, Paul, Apriletti, James W, Scanlan, Thomas S

Volltext

Rational Design and Synthesis of a Novel Thyroid Hormone Antagonist That Blocks Coactivator Recruitment von Nguyen, Ngoc-Ha, Apriletti, James W, Cunha Lima, Suzana T, Webb, Paul, Baxter, John D, Scanlan, Thomas S

Volltext

Structural Determinants of Selective Thyromimetics von Yoshihara, Hikari A. I, Apriletti, James W, Baxter, John D, Scanlan, Thomas S

Volltext

Design of thyroid hormone receptor antagonists from first principles von Webb, Paul, Nguyen, Ngoc-Ha, Chiellini, Grazia, Yoshihara, Hikari A.I., Cunha Lima, Suzana T., Apriletti, James W., Ribeiro, Ralff C.J., Marimuthu, Adhirai, West, Brian L., Goede, Patrick, Mellstrom, Karin, Nilsson, Stefan, Kushner, Peter J., Fletterick, Robert J., Scanlan, Thomas S., Baxter, John D.

Volltext

X-ray crystallographic and functional studies of thyroid hormone receptor von Ribeiro, Ralff C.J, Apriletti, James W, Wagner, Richard L, Feng, Weijun, Kushner, Peter J, Nilsson, Stefan, Scanlan, Thomas S, West, Brian L, Fletterick, Robert J, Baxter, John D

Volltext