Double-stranded RNAs containing multiple IU pairs are sufficient to suppress interferon induction and apoptosis von Vitali, Patrice, Scadden, A D J

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The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA von Mannion, Niamh M., Greenwood, Sam M., Young, Robert, Cox, Sarah, Brindle, James, Read, David, Nellåker, Christoffer, Vesely, Cornelia, Ponting, Chris P., McLaughlin, Paul J., Jantsch, Michael F., Dorin, Julia, Adams, Ian R., Scadden, A.D.J., Öhman, Marie, Keegan, Liam P., O’Connell, Mary A.

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Tudor-SN and ADAR1 are components of cytoplasmic stress granules von Weissbach, Rebekka, Scadden, A D J

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The RISC subunit Tudor-SN binds to hyper-edited double-stranded RNA and promotes its cleavage von Scadden, A D J

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Proteins that contain a functional Z-DNA-binding domain localize to cytoplasmic stress granules von Ng, Siew Kit, Weissbach, Rebekka, Ronson, George E, Scadden, A D J

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Inosine-Containing dsRNA Binds a Stress-Granule-like Complex and Downregulates Gene Expression In trans von Scadden, A.D.J.

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The PTB interacting protein raver1 regulates α-tropomyosin alternative splicing von Gromak, Natalia, Rideau, Alexis, Southby, Justine, Scadden, A. D. J., Gooding, Clare, Hüttelmaier, Stefan, Singer, Robert H., Smith, Christopher W. J.

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Cleavage of dsRNAs hyper-edited by ADARs occurs at preferred editing sites von Scadden, A. D. J., O'Connell, M. A.

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RNAi is antagonized by A→I hyper-editing von Scadden, A D J, Smith, Christopher W J

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A ribonuclease specific for inosine-containing RNA: a potential role in antiviral defence? von Scadden, A. D. J., Smith, Christopher W. J.

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Cleavage occurs preferentially between the IU and UI pair in the IIUI sequence von A. D. J. Scadden, M. A. O'Connell

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2′-OH groups are important for cleavage von A. D. J. Scadden, M. A. O'Connell

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Editing by ADAR1, ADAR2 or dADAR generates the IIUI sequence von A. D. J. Scadden, M. A. O'Connell

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GU pairs have a deleterious effect on cleavage von A. D. J. Scadden, M. A. O'Connell

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IIUI is better than the 4I site for cleavage von A. D. J. Scadden, M. A. O'Connell

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Cleavage of IIUI dsRNA occurs on both strands within a single molecule von A. D. J. Scadden, M. A. O'Connell

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Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment von Kfoury, Youmna, Baryawno, Ninib, Severe, Nicolas, Mei, Shenglin, Gustafsson, Karin, Hirz, Taghreed, Brouse, Thomas, Scadden, Elizabeth W., Igolkina, Anna A., Kokkaliaris, Konstantinos, Choi, Bryan D., Barkas, Nikolas, Randolph, Mark A., Shin, John H., Saylor, Philip J., Scadden, David T., Sykes, David B., Kharchenko, Peter V.

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A transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma von Alchahin, Adele M., Mei, Shenglin, Tsea, Ioanna, Hirz, Taghreed, Kfoury, Youmna, Dahl, Douglas, Wu, Chin-Lee, Subtelny, Alexander O., Wu, Shulin, Scadden, David T., Shin, John H., Saylor, Philip J., Sykes, David B., Kharchenko, Peter V., Baryawno, Ninib

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Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses von Hirz, Taghreed, Mei, Shenglin, Sarkar, Hirak, Kfoury, Youmna, Wu, Shulin, Verhoeven, Bronte M., Subtelny, Alexander O., Zlatev, Dimitar V., Wszolek, Matthew W., Salari, Keyan, Murray, Evan, Chen, Fei, Macosko, Evan Z., Wu, Chin-Lee, Scadden, David T., Dahl, Douglas M., Baryawno, Ninib, Saylor, Philip J., Kharchenko, Peter V., Sykes, David B.

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Osteoblastic cells regulate the haematopoietic stem cell niche von Calvi, L. M., Adams, G. B., Weibrecht, K. W., Weber, J. M., Olson, D. P., Knight, M. C., Martin, R. P., Schipani, E., Divieti, P., Bringhurst, F. R., Milner, L. A., Kronenberg, H. M., Scadden, D. T.

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