Chronic Myeloid Leukemia von Sawyers, Charles L

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Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and PI3K/Akt pathway activation in glioblastoma and prostate cancer von Mehrian-Shai, R, Chen, C.D, Shi, T, Horvath, S, Nelson, S.F, Reichardt, J.K.V, Sawyers, C.L

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Clinical Resistance to STI-571 Cancer Therapy Caused by BCR-ABL Gene Mutation or Amplification von Gorre, Mercedes E., Mohammed, Mansoor, Ellwood, Katharine, Hsu, Nicholas, Paquette, Ron, Rao, P. Nagesh, Sawyers, Charles L.

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Targeted cancer therapy von Sawyers, Charles

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Towards a global cancer knowledge network: dissecting the current international cancer genomic sequencing landscape von Vis, D.J., Lewin, J., Liao, R.G., Mao, M., Andre, F., Ward, R.L., Calvo, F., Teh, B.T., Camargo, A.A., Knoppers, B.M., Sawyers, C.L., Wessels, L.F.A., Lawler, M., Siu, L.L., Voest, E.

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The phosphatidylinositol 3-Kinase–AKT pathway in human cancer von Vivanco, Igor, Sawyers, Charles L.

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A cytoplasmic inhibitor of the JNK signal transduction pathway von Dickens, M. (University of Massachusetts Medical School, Worcester, MA.), Rogers, J.S, Cavanagh, J, Raitano, A, Xia, Z, Halpern, J.R, Greenberg, M.E, Sawyers, C.L, Davis, R.J

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Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome von Druker, Brian J, Sawyers, Charles L, Kantarjian, Hagop, Resta, Debra J, Reese, Sofia Fernandes, Ford, John M, Capdeville, Renaud, Talpaz, Moshe

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Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia von Druker, Brian J, Talpaz, Moshe, Resta, Debra J, Peng, Bin, Buchdunger, Elisabeth, Ford, John M, Lydon, Nicholas B, Kantarjian, Hagop, Capdeville, Renaud, Ohno-Jones, Sayuri, Sawyers, Charles L

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Evidence for clonal outgrowth of androgen-independent prostate cancer cells from androgen-dependent tumors through a two-step process von CRAFT, N, CHHOR, C, TRAN, C, BELLDEGRUN, A, DEKERNION, J, WITTE, O. N, SAID, J, REITER, R. E, SAWYERS, C. L

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A distinct epigenetic state sensitizes enzalutamide-resistant prostate cancer cells to BET bromodomain inhibition von Shah, N, Arora, V.K, Karthaus, W, Wongvipat, J, Zheng, D, Sawyers, C

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Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study von Sawyers, Charles L., Hochhaus, Andreas, Feldman, Eric, Goldman, John M., Miller, Carole B., Ottmann, Oliver G., Schiffer, Charles A., Talpaz, Moshe, Guilhot, Francois, Deininger, Michael W.N., Fischer, Thomas, O'Brien, Steve G., Stone, Richard M., Gambacorti-Passerini, Carlo B., Russell, Nigel H., Reiffers, Jose J., Shea, Thomas C., Chapuis, Bernard, Coutre, Steven, Tura, Sante, Morra, Enrica, Larson, Richard A., Saven, Alan, Peschel, Christian, Gratwohl, Alois, Mandelli, Franco, Ben-Am, Monique, Gathmann, Insa, Capdeville, Renaud, Paquette, Ronald L., Druker, Brian J.

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Enhanced Sensitivity of PTEN-Deficient Tumors to Inhibition of FRAP/mTOR von Neshat, Mehran S., Mellinghoff, Ingo K., Tran, Chris, Stiles, Bangyan, Thomas, George, Petersen, Roseann, Frost, Philip, Gibbons, James J., Wu, Hong, Sawyers, Charles L.

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A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase von Craft, Noah, Shostak, Yuriy, Carey, Michael, Sawyers, Charles L.

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Molecular determinants of resistance to antiandrogen therapy von Chen, Charlie D, Welsbie, Derek S, Tran, Chris, Baek, Sung Hee, Chen, Randy, Vessella, Robert, Rosenfeld, Michael G, Sawyers, Charles L

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The Bcr-Abl Leukemia Oncogene Activates Jun Kinase and Requires Jun for Transformation von Raitano, Arthur B., Halpern, Jocelyn R., Hambuch, Tina M., Sawyers, Charles L.

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Rational therapeutic intervention in cancer: kinases as drug targets von Sawyers, Charles L

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Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1–2 study von Scher, Howard I, Prof, Beer, Tomasz M, MD, Higano, Celestia S, MD, Anand, Aseem, MA, Taplin, Mary-Ellen, MD, Efstathiou, Eleni, MD, Rathkopf, Dana, MD, Shelkey, Julia, BS, Yu, Evan Y, MD, Alumkal, Joshi, MD, Hung, David, MD, Hirmand, Mohammad, MD, Seely, Lynn, MD, Morris, Michael J, MD, Danila, Daniel C, MD, Humm, John, PhD, Larson, Steve, MD, Fleisher, Martin, PhD, Sawyers, Charles L, MD

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Research on Resistance to Cancer Drug Gleevec von Sawyers, Charles L.

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The PTEN/MMAC1 Tumor Suppressor Phosphatase Functions as a Negative Regulator of the Phosphoinositide 3-Kinase/Akt Pathway von Wu, Xinyi, Senechal, Kristen, Neshat, Mehran S., Whang, Young E., Sawyers, Charles L.

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