Discovery of Potent and Selective SH2 Inhibitors of the Tyrosine Kinase ZAP-70 von Vu, Chi B, Corpuz, Evelyn G, Merry, Taylor J, Pradeepan, Selvaluxmi G, Bartlett, Catherine, Bohacek, Regine S, Botfield, Martyn C, Eyermann, Charles J, Lynch, Berkley A, MacNeil, Ian A, Ram, Mary K, van Schravendijk, Marie Rose, Violette, Shelia, Sawyer, Tomi K

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Identification of Src-specific phosphorylation site on focal adhesion kinase: Dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavi... von BRUNTON, Valerie G, AVIZIENYTE, Egle, FINCHAM, Valerie J, SERRELS, Bryan, METCALF, Chester A, SAWYER, Tomi K, FRAME, Margaret C

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Inhibition of wild-type and mutant Bcr-Abl by AP23464, a potent ATP-based oncogenic protein kinase inhibitor: implications for CML von O'Hare, Thomas, Pollock, Roy, Stoffregen, Eric P., Keats, Jeffrey A., Abdullah, Omar M., Moseson, Erika M., Rivera, Victor M., Tang, Hao, Metcalf, Chester A., Bohacek, Regine S., Wang, Yihan, Sundaramoorthi, Raji, Shakespeare, William C., Dalgarno, David, Clackson, Tim, Sawyer, Tomi K., Deininger, Michael W., Druker, Brian J.

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Cancer metastasis therapeutic targets and drug discovery: emerging small-molecule protein kinase inhibitors von Sawyer, Tomi K

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AP23846, a novel and highly potent Src family kinase inhibitor, reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines and abrogate... von Summy, Justin M, Trevino, Jose G, Lesslie, Donald P, Baker, Cheryl H, Shakespeare, William C, Wang, Yihan, Sundaramoorthi, Raji, Metcalf, 3rd, Chester A, Keats, Jeffrey A, Sawyer, Tomi K, Gallick, Gary E

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Src homology-2 domains: Structure, mechanisms, and drug discovery von Sawyer, Tomi K.

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New screening tools for lead compound identification von Sawyer, Tomi K

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Chemical Biology and Drug Design: three-dimensional, dynamic, and mechanistic nature of two multidisciplinary fields von Sawyer, Tomi K.

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In vitro and in vivo activity of ATP-based kinase inhibitors AP23464 and AP23848 against activation-loop mutants of Kit von Corbin, Amie S., Demehri, Shadmehr, Griswold, Ian J., Wang, Yihan, Metcalf, Chester A., Sundaramoorthi, Raji, Shakespeare, William C., Snodgrass, Joseph, Wardwell, Scott, Dalgarno, David, Iuliucci, John, Sawyer, Tomi K., Heinrich, Michael C., Druker, Brian J., Deininger, Michael W.N.

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Chemical Biology and Drug Design: World Project Initiative von Sawyer, Tomi K.

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Chemical Biology & Drug Design: Special Thematic Issues on a Molecular Armamentarium of Novel Chemical and Biological Medicines for the War on Disease and Innovative Technologies E... von Sawyer, Tomi K.

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Chemical Biology & Drug Design: Inaugural issue von Sawyer, Tomi K.

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Inimitable Elements of Innovative Drug Discovery: Quest for Knowledge, Passion for Life von Sawyer, Tomi K.

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Protein Tyrosine Phosphatase Substrate Specificity: Size and Phosphotyrosine Positioning Requirements in Peptide Substrates von Zhang, Zhong Yin, Maclean, Derek, McNamara, Dennis J, Sawyer, Tomi K, Dixon, Jack E

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Bone-Targeted 2,6,9-Trisubstituted purines: novel inhibitors of Src tyrosine kinase for the treatment of bone diseases von Wang, Yihan, Metcalf, Chester A., Shakespeare, William C., Sundaramoorthi, Raji, Keenan, Terence P., Bohacek, Regine S., van Schravendijk, Marie Rose, Violette, Shiela M., Narula, Surinder S., Dalgarno, David C., Haraldson, Chad, Keats, Jeffrey, Liou, Shuenn, Mani, Ukti, Pradeepan, Selvi, Ram, Mary, Adams, Susan, Weigele, Manfred, Sawyer, Tomi K.

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Discovery of Prototype Peptidomimetic Agonists at the Human Melanocortin Receptors MC1R and MC4R von Haskell-Luevano, Carrie, Hendrata, Siska, North, Cheryl, Sawyer, Tomi K, Hadley, Mac E, Hruby, Victor J, Dickinson, Chris, Gantz, Ira

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Peptide Revolution: Genomics, Proteomics and Therapeutics von Sawyer, T.K, Chorev, M

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A study of Src SH2 domain protein—phosphopeptide binding interactions by electrospray ionization mass spectrometry von Loo, Joseph A., Peifeng, Hu, McConnell, Patrick, Tom Mueller, W., Sawyer, Tomi K., Thanabal, Venkataraman

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Substrate Specificity of the Protein Tyrosine Phosphatases von Zhang, Zhong-Yin, Thieme-Sefler, Andrea M., Maclean, Derek, McNamara, Dennis J., Dobrusin, Ellen M., Sawyer, Tomi K., Dixon, Jack E.

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A Synthetic HIV-1 Protease Inhibitor with Antiviral Activity Arrests HIV-Like Particle Maturation von McQuade, T. J., Tomasselli, A. G., Liu, L., Karacostas, V., Moss, B., Sawyer, T. K., Heinrikson, R. L., Tarpley, W. G.

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