Cord blood NK cells engineered to express IL-15 and a CD19-targeted CAR show long-term persistence and potent antitumor activity von Liu, E, Tong, Y, Dotti, G, Shaim, H, Savoldo, B, Mukherjee, M, Orange, J, Wan, X, Lu, X, Reynolds, A, Gagea, M, Banerjee, P, Cai, R, Bdaiwi, M H, Basar, R, Muftuoglu, M, Li, L, Marin, D, Wierda, W, Keating, M, Champlin, R, Shpall, E, Rezvani, K

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Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma leukemia effects and safety von Hoyos, V, Savoldo, B, Quintarelli, C, Mahendravada, A, Zhang, M, Vera, J, Heslop, H E, Rooney, C M, Brenner, M K, Dotti, G

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Generation of multi-leukemia antigen-specific T cells to enhance the graft-versus-leukemia effect after allogeneic stem cell transplant von Weber, G, Gerdemann, U, Caruana, I, Savoldo, B, Hensel, N F, Rabin, K R, Shpall, E J, Melenhorst, J J, Leen, A M, Barrett, A J, Bollard, C M

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Immunotherapy in the Treatment of Human Solid Tumors: Basic and Translational Aspects von Olive, D., Savoldo, B., Pastorino, F., Castriconi, R.

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The immunogenicity of virus-derived 2A sequences in immunocompetent individuals von Arber, C, Abhyankar, H, Heslop, H E, Brenner, M K, Liu, H, Dotti, G, Savoldo, B

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CD30‐CHIMERIC ANTIGEN RECEPTOR (CAR) T CELLS FOR THERAPY OF HODGKIN LYMPHOMA (HL) von Ramos, C.A., Torrano, V., Bilgi, M., Gerken, C., Dakhova, O., Mei, Z., Wu, M., Grilley, B., Gee, A.P., Rooney, C.M., Dotti, G., Savoldo, B., Heslop, H.E., Brenner, M.K.

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Direct comparison of in vivo fate of second and third-generation CD19-specific chimeric antigen receptor (CAR)-T cells in patients with b cell non-hodgkin lymphoma (B-NHL): Reversa... von Gomes da Silva, D, Mukherjee, M, Madhuwanti, S, Dakhova, O, Liu, H, Grilley, B, Gee, A, Neelapu, S.S, Rooney, C, Heslop, H, Savoldo, B, Dotti, G, Brenner, M, Mamonkin, M, Ramos, C.A

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Late donor cardiectomy after paediatric heterotopic cardiac transplantation von Tsang, V, FRCS, Yacoub, M, Prof, Sridharan, S, Burch, M, FRCP, Radley-Smith, R, FRCP, Khaghani, A, FRCS, Savoldo, B, MD, Amrolia, PJ, FRCP

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Chimeric Antigen Receptor Gene-Modified Virus-Specific T-Cell Expanded in Patients with Reactivated Epstein-Barr Virus Post Allogeneic Stem Cell Transplant von Lapteva, N, Gilbert, M, Hiregange, M, Diaconu, I, Dakhova, O, Rouce, R, Rollins, L, Liu, H, Savoldo, B, Durett, A, Krance, R.A, Heslop, H, Gee, A, Ramos, C, Rooney, C

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Generation and administration of autologous T cells transduced with a 3rd generation GD2 chimeric antigen receptor for patients with relapsed or refractory neuroblastoma von Louis, C.U, Savoldo, B, Heczey, A, Yvon, E, Gee, A, Rooney, C, Heslop, H, Dotti, G, Brenner, M.K

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Selective elimination of a chemoresistant side population of B-CLL cells by cytotoxic T lymphocytes in subjects receiving an autologous hCD40L IL-2 tumor vaccine von Foster, A E, Okur, F V, Biagi, E, Lu, A, Dotti, G, Yvon, E, Savoldo, B, Carrum, G, Goodell, M A, Heslop, H E, Brenner, M K

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Generation of EBV-Specific CD4+ Cytotoxic T Cells from Virus Naive Individuals von Savoldo, Barbara, Cubbage, Michael L, Durett, April G, Goss, John, Huls, M. Helen, Liu, Zhensheng, Teresita, Lopez, Gee, Adrian P, Ling, Paul D, Brenner, Malcolm K, Heslop, Helen E, Rooney, Cliona M

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Fifteen Years of Gene Therapy Based on Chimeric Antigen Receptors: Are We Nearly There Yet? von DOTTI, Gianpietro, SAVOLDO, Barbara, BRENNER, Malcolm

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Improving immune reconstitution after cord blood transplantation using ex vivo expanded virus-specific T cells: a phase I clinical study von Hanley, P.J, Martinez, C, Cruz, R, Lam, S, Savoldo, B, Dotti, G, Brenner, M, Rooney, C, Heslop, H, Krance, R, Shpall, E.J, Bollard, C.M

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Naïve T-cell-derived CTL recognize atypical epitopes of CMVpp65 with higher avidity than CMV-seropositive donor-derived CTL - a basis for treatment of post-transplant viral infecti... von Hanley, P.J, Cruz, R.Y, Melenhorst, J, Scheinberg, P, Blaney, J, Savoldo, B, Dotti, G, Heslop, H, Rooney, C, Shpall, E.J, Barrett, J.A, Rodgers, J, Bollard, C.M

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Ultra low-dose IL-2 mediated expansion of regulatory T cells as GvHD prophylaxis for recipients of allogeneic hematopoietic stem cells von Ku, S, Kennedy-Nasser, A.A, Hazrat, Y, Melenhorst, J, Barrett, A, Ito, S, Durett, A.G, Foster, A, Savoldo, B, Yvon, E, Heslop, H.E, Carrum, G, Kamble, R.T, Brenner, M.K, Krance, R.A, Bollard, C.M

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Infusion of CD19-directed/multivirus specific-cytotoxic T lymphocytes after allogeneic hematopoietic stem cell transplantation for B cell malignancies von Cruz, C.R, Micklethwaite, K.P, Savoldo, B, Lam, S, Ku, S, Krance, R.A, Diouf, O, Leen, A.M, Kamble, R.T, Kennedy-Nasser, A, Barrett, J, Shpall, E, Heslop, H.E, Rooney, C.M, Brenner, M.K, Bollard, C.M, Dotti, G

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Immunotherapy: B7H3-CAR NK CELLS AND DNR CO-TRANSDUCED NK SHOWS MAINTAIN THEIR POTENCY AGAINST TGF-B MEDIATED IMMUNE SUPPRESSION von Chaudhry, K., Geiger, A., Dowlati, E., Lang, H., Yvon, E., Holdoff, M., Jones, R., Savoldo, B., Cruz, C., Bollard, C.

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Genetic modification of human T lymphocytes for the treatment of hematologic malignancies von HOYOS, Valentina, SAVOLDO, Barbara, DOTTI, Gianpietro

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Human antibody titers to Epstein–Barr Virus (EBV) gp350 correlate with neutralization of infectivity better than antibody titers to EBV gp42 using a rapid flow cytometry-based EBV... von Sashihara, Junji, Burbelo, Peter D, Savoldo, Barbara, Pierson, Theodore C, Cohen, Jeffrey I

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