The importance of adherence in tuberculosis treatment clinical trials and its relevance in explanatory and pragmatic trials von Vernon, Andrew, Fielding, Katherine, Savic, Rada, Dodd, Lori, Nahid, Payam

Volltext

Pharmacokinetics, optimal dosing, and safety of linezolid in children with multidrug-resistant tuberculosis: Combined data from two prospective observational studies von Garcia-Prats, Anthony J, Schaaf, H Simon, Draper, Heather R, Garcia-Cremades, Maria, Winckler, Jana, Wiesner, Lubbe, Hesseling, Anneke C, Savic, Rada M

Volltext

Is Glycemic Control the Secret to Tuberculosis Control? von Huddart, Sophie, Savic, Rada M., Cattamanchi, Adithya

Volltext

A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis von Imperial, Marjorie Z., Nahid, Payam, Phillips, Patrick P. J., Davies, Geraint R., Fielding, Katherine, Hanna, Debra, Hermann, David, Wallis, Robert S., Johnson, John L., Lienhardt, Christian, Savic, Rada M.

Volltext

Exploring the Potential of a Smart Ring to Predict Postoperative Pain Outcomes in Orthopedic Surgery Patients von Morimoto, Michael, Nawari, Ashraf, Savic, Rada, Marmor, Meir

Volltext

High-resolution mapping of fluoroquinolones in TB rabbit lesions reveals specific distribution in immune cell types von Blanc, Landry, Daudelin, Isaac B, Podell, Brendan K, Chen, Pei-Yu, Zimmerman, Matthew, Martinot, Amanda J, Savic, Rada M, Prideaux, Brendan, Dartois, Véronique

Volltext

Development of New Tuberculosis Drugs: Translation to Regimen Composition for Drug-Sensitive and Multidrug-Resistant Tuberculosis von Ernest, Jacqueline P, Strydom, Natasha, Wang, Qianwen, Zhang, Nan, Nuermberger, Eric, Dartois, Véronique, Savic, Rada M

Volltext

Analysis of Dynamic Efficacy Endpoints of the Nix-TB Trial von Solans, Belén P, Imperial, Marjorie Z, Olugbosi, Morounfolu, Savic, Rada M

Volltext

Emerging Therapeutics, Technologies, and Drug Development Strategies to Address Patient Nonadherence and Improve Tuberculosis Treatment von Garcia-Cremades, Maria, Solans, Belen P, Strydom, Natasha, Vrijens, Bernard, Pillai, Goonaseelan Colin, Shaffer, Craig, Thomas, Bruce, Savic, Rada M

Volltext

Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study von Elliott, Julian H, MBBS, McMahon, James H, MBBS, Chang, Christina C, MBBS, Lee, Sulggi A, MD, Hartogensis, Wendy, PhD, Bumpus, Namandje, PhD, Savic, Rada, PhD, Roney, Janine, MPH, Hoh, Rebecca, BA, Solomon, Ajantha, BSc, Piatak, Michael, PhD, Gorelick, Robert J, PhD, Lifson, Jeff, PhD, Bacchetti, Peter, Prof, Deeks, Steven G, Prof, Lewin, Sharon R, Prof

Volltext

Mechanistic Modeling of Mycobacterium tuberculosis Infection in Murine Models for Drug and Vaccine Efficacy Studies von Zhang, Nan, Strydom, Natasha, Tyagi, Sandeep, Soni, Heena, Tasneen, Rokeya, Nuermberger, Eric L., Savic, Rada M.

Volltext

Association of busulfan exposure with survival and toxicity after haemopoietic cell transplantation in children and young adults: a multicentre, retrospective cohort analysis von Bartelink, Imke H, PhD, Lalmohamed, Arief, PharmD, van Reij, Elisabeth M L, PharmD, Dvorak, Christopher C, MD, Savic, Rada M, PhD, Zwaveling, Juliette, PharmD, Bredius, Robbert G M, MD, Egberts, Antoine C G, Prof, Bierings, Marc, MD, Kletzel, Morris, MD, Shaw, Peter J, MD, Nath, Christa E, PhD, Hempel, George, MD, Ansari, Marc, MD, Krajinovic, Maja, Prof, Théorêt, Yves, PhD, Duval, Michel, Prof, Keizer, Ron J, PharmD, Bittencourt, Henrique, MD, Hassan, Moustapha, MD, Güngör, Tayfun, MD, Wynn, Robert F, MD, Veys, Paul, MD, Cuvelier, Geoff D E, MD, Marktel, Sarah, MD, Chiesa, Robert, MD, Cowan, Morton J, MD, Slatter, Mary A, MD, Stricherz, Melisa K, PharmD, Jennissen, Cathryn, PharmD, Long-Boyle, Janel R, PharmD, Boelens, Jaap Jan, Dr

Volltext

Designing Drug Trials: Considerations for Pregnant Women von Sheffield, Jeanne S., Siegel, David, Mirochnick, Mark, Heine, R. Phillips, Nguyen, Christine, Bergman, Kimberly L., Savic, Rada M., Long, Jill, Dooley, Kelly E., Nesin, Mirjana

Volltext

Population Pharmacokinetics and Pharmacodynamics of Pegozafermin in Patients with Nonalcoholic Steatohepatitis von Tseng, Chih-Ming Leo, Balic, Kemal, Charlton, R Will, Margalit, Maya, Mansbach, Hank, Savic, Rada M

Volltext

Identifying an optimal dihydroartemisinin-piperaquine dosing regimen for malaria prevention in young Ugandan children von Wallender, Erika, Ali, Ali Mohamed, Hughes, Emma, Kakuru, Abel, Jagannathan, Prasanna, Muhindo, Mary Kakuru, Opira, Bishop, Whalen, Meghan, Huang, Liusheng, Duvalsaint, Marvin, Legac, Jenny, Kamya, Moses R., Dorsey, Grant, Aweeka, Francesca, Rosenthal, Philip J., Savic, Rada M.

Volltext

Pragmatic global dosing recommendations for the 3-month, once-weekly rifapentine and isoniazid preventive TB regimen in children von Radtke, Kendra K., Hibma, Jennifer E., Hesseling, Anneke C., Savic, Rada M.

Volltext

A Rapid Pharmacogenomic Assay to Detect NAT2 Polymorphisms and Guide Isoniazid Dosing for Tuberculosis Treatment von Verma, Renu, Patil, Sunita, Zhang, Nan, Moreira, Flora M. F., Vitorio, Marize T., Santos, Andrea da S., Wallace, Ellen, Gnanashanmugam, Devasena, Persing, David H., Savic, Rada M., Croda, Julio, Andrews, Jason R.

Volltext

Comparative Efficacy of Rifapentine Alone and in Combination with Isoniazid for Latent Tuberculosis Infection: a Translational Pharmacokinetic-Pharmacodynamic Modeling Study von Radtke, Kendra K., Ernest, Jacqueline P., Zhang, Nan, Ammerman, Nicole C., Nuermberger, Eric, Belknap, Robert, Boyd, Rosanna, Sterling, Timothy R., Savic, Rada M.

Volltext

Pharmacodynamic Correlates of Linezolid Activity and Toxicity in Murine Models of Tuberculosis von Bigelow, Kristina M, Deitchman, Amelia N, Li, Si-Yang, Barnes-Boyle, Kala, Tyagi, Sandeep, Soni, Heena, Dooley, Kelly E, Savic, Rada M, Nuermberger, Eric L

Volltext

QT Interval Prolongation with One or More QT-Prolonging Agents Used as Part of a Multidrug Regimen for Rifampicin-Resistant Tuberculosis Treatment: Findings from Two Pediatric Stud... von Ali, Ali Mohamed, Radtke, Kendra K, Hesseling, Anneke C, Winckler, Jana, Schaaf, H Simon, Draper, Heather R, Solans, Belén P, van der Laan, Louvina, Hughes, Jennifer, Fourie, Barend, Nielsen, James, Garcia-Prats, Anthony J, Savic, Rada M

Volltext