Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart von Jabs, Markus, Rose, Adam J, Lehmann, Lorenz H, Taylor, Jacqueline, Moll, Iris, Sijmonsma, Tjeerd P, Herberich, Stefanie E, Sauer, Sven W, Poschet, Gernot, Federico, Giuseppina, Mogler, Carolin, Weis, Eva-Maria, Augustin, Hellmut G, Yan, Minhong, Gretz, Norbert, Schmid, Roland M, Adams, Ralf H, Gröne, Hermann-Joseph, Hell, Rüdiger, Okun, Jürgen G, Backs, Johannes, Nawroth, Peter P, Herzig, Stephan, Fischer, Andreas

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T cell Activation Is Driven by an ADP-Dependent Glucokinase Linking Enhanced Glycolysis with Mitochondrial Reactive Oxygen Species Generation von Kamiński, Marcin M., Sauer, Sven W., Kamiński, Marian, Opp, Silvana, Ruppert, Thorsten, Grigaravičius, Paulius, Grudnik, Przemysław, Gröne, Hermann-Josef, Krammer, Peter H., Gülow, Karsten

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DHTKD1 Mutations Cause 2-Aminoadipic and 2-Oxoadipic Aciduria von Danhauser, Katharina, Sauer, Sven W., Haack, Tobias B., Wieland, Thomas, Staufner, Christian, Graf, Elisabeth, Zschocke, Johannes, Strom, Tim M., Traub, Thorsten, Okun, Jürgen G., Meitinger, Thomas, Hoffmann, Georg F., Prokisch, Holger, Kölker, Stefan

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QDPR homologues in Danio rerio regulate melanin synthesis, early gliogenesis, and glutamine homeostasis von Breuer, Maximilian, Guglielmi, Luca, Zielonka, Matthias, Hemberger, Verena, Kölker, Stefan, Okun, Jürgen G, Hoffmann, Georg F, Carl, Matthias, Sauer, Sven W, Opladen, Thomas

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The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration von Gdynia, Georg, Sauer, Sven W., Kopitz, Jürgen, Fuchs, Dominik, Duglova, Katarina, Ruppert, Thorsten, Miller, Matthias, Pahl, Jens, Cerwenka, Adelheid, Enders, Markus, Mairbäurl, Heimo, Kamiński, Marcin M., Penzel, Roland, Zhang, Christine, Fuller, Jonathan C., Wade, Rebecca C., Benner, Axel, Chang-Claude, Jenny, Brenner, Hermann, Hoffmeister, Michael, Zentgraf, Hanswalter, Schirmacher, Peter, Roth, Wilfried

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Current concepts in organic acidurias: understanding intra- and extracerebral disease manifestation von Kölker, Stefan, Burgard, Peter, Sauer, Sven W., Okun, Jürgen G.

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Secondary mitochondrial dysfunction in propionic aciduria: a pathogenic role for endogenous mitochondrial toxins von Schwab, Marina A, Sauer, Sven W, Okun, Jürgen G, Nijtmans, Leo G J, Rodenburg, Richard J T, van den Heuvel, Lambert P, Dröse, Stefan, Brandt, Ulrich, Hoffmann, Georg F, Ter Laak, Henk, Kölker, Stefan, Smeitink, Jan A M

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Renal dysfunction in methylmalonic acidurias: review for the pediatric nephrologist von Morath, Marina A., Hörster, Friederike, Sauer, Sven W.

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Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism von Bezerra, Gustavo A., Foster, William R., Bailey, Henry J., Hicks, Kevin G., Sauer, Sven W., Dimitrov, Bianca, McCorvie, Thomas J., Okun, Jrgen G., Rutter, Jared, Kolker, Stefan, Yue, Wyatt W.

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Understanding cerebral L-lysine metabolism: the role of L-pipecolate metabolism in Gcdh-deficient mice as a model for glutaric aciduria type I von Posset, Roland, Opp, Silvana, Struys, Eduard A., Völkl, Alfred, Mohr, Heribert, Hoffmann, Georg F., Kölker, Stefan, Sauer, Sven W., Okun, Jürgen G.

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Glutaric aciduria type I and methylmalonic aciduria: Simulation of cerebral import and export of accumulating neurotoxic dicarboxylic acids in in vitro models of the blood–brain ba... von Sauer, Sven W., Opp, Silvana, Mahringer, Anne, Kamiński, Marcin M., Thiel, Christian, Okun, Jürgen G., Fricker, Gert, Morath, Marina A., Kölker, Stefan

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Intracerebral accumulation of glutaric and 3-hydroxyglutaric acids secondary to limited flux across the blood-brain barrier constitute a biochemical risk factor for neurodegenerati... von Sauer, Sven W, Okun, Jürgen G, Fricker, Gert, Mahringer, Anne, Müller, Ines, Crnic, Linda R, Mühlhausen, Chris, Hoffmann, Georg F, Hörster, Friederike, Goodman, Stephen I, Harding, Cary O, Koeller, David M, Kölker, Stefan

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A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway von Lehmann, Lorenz H, Jebessa, Zegeye H, Kreusser, Michael M, Horsch, Axel, He, Tao, Kronlage, Mariya, Dewenter, Matthias, Sramek, Viviana, Oehl, Ulrike, Krebs-Haupenthal, Jutta, von der Lieth, Albert H, Schmidt, Andrea, Sun, Qiang, Ritterhoff, Julia, Finke, Daniel, Völkers, Mirko, Jungmann, Andreas, Sauer, Sven W, Thiel, Christian, Nickel, Alexander, Kohlhaas, Michael, Schäfer, Michaela, Sticht, Carsten, Maack, Christoph, Gretz, Norbert, Wagner, Michael, El-Armouche, Ali, Maier, Lars S, Londoño, Juan E Camacho, Meder, Benjamin, Freichel, Marc, Gröne, Hermann-Josef, Most, Patrick, Müller, Oliver J, Herzig, Stephan, Furlong, Eileen E M, Katus, Hugo A, Backs, Johannes

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Mitochondrial reactive oxygen species control T cell activation by regulating IL-2 and IL-4 expression: mechanism of ciprofloxacin-mediated immunosuppression von Kaminski, Marcin M, Sauer, Sven W, Klemke, Claus-Detlev, Süss, Dorothee, Okun, Jürgen G, Krammer, Peter H, Gülow, Karsten

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Iron Regulatory Proteins Secure Mitochondrial Iron Sufficiency and Function von Galy, Bruno, Ferring-Appel, Dunja, Sauer, Sven W., Kaden, Sylvia, Lyoumi, Saïd, Puy, Herve, Kölker, Stefan, Gröne, Hermann-Josef, Hentze, Matthias W.

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Therapeutic modulation of cerebral L-lysine metabolism in a mouse model for glutaric aciduria type I von SAUER, Sven W, OPP, Silvana, HOFFMANN, Georg F, KOELLER, David M, KUN, Jürgen G, KÖLKER, Stefan

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Xanthohumol-induced transient superoxide anion radical formation triggers cancer cells into apoptosis via a mitochondria-mediated mechanism von Strathmann, Julia, Klimo, Karin, Sauer, Sven W, Okun, Jürgen G, Prehn, Jochen H.M, Gerhäuser, Clarissa

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Impairment of astrocytic glutaminolysis in glutaric aciduria type I von Komatsuzaki, Shoko, Ediga, Raga Deepthi, Okun, Jürgen G., Kölker, Stefan, Sauer, Sven W.

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Cellular citrate levels establish a regulatory link between energy metabolism and the hepatic iron hormone hepcidin von da Silva, Ana Rita, Neves, Joana, Mleczko-Sanecka, Katarzyna, Tandon, Amol, Sauer, Sven W., Hentze, Matthias W., Muckenthaler, Martina U.

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Multifactorial modulation of susceptibility to l-lysine in an animal model of glutaric aciduria type I von Sauer, Sven W., Opp, Silvana, Komatsuzaki, Shoko, Blank, Anna-Eva, Mittelbronn, Michel, Burgard, Peter, Koeller, D.M., Okun, Jürgen G., Kölker, Stefan

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