Production of Site-Specific Antibody–Drug Conjugates Using Optimized Non-Natural Amino Acids in a Cell-Free Expression System von Zimmerman, Erik S, Heibeck, Tyler H, Gill, Avinash, Li, Xiaofan, Murray, Christopher J, Madlansacay, Mary Rose, Tran, Cuong, Uter, Nathan T, Yin, Gang, Rivers, Patrick J, Yam, Alice Y, Wang, Willie D, Steiner, Alexander R, Bajad, Sunil U, Penta, Kalyani, Yang, Wenjin, Hallam, Trevor J, Thanos, Christopher D, Sato, Aaron K

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Discovery of a potent, selective, and tumor-suppressing antibody antagonist of adenosine A2A receptor von Wang, Linya, Garg, Pankaj, Chan, Kara Y, Yuan, Tom Z, Lujan Hernandez, Ana G, Han, Zhen, Peterson, Sean M, Tuscano, Emily, Safavi, Crystal, Kwan, Eric, Villalta, Mouna, Mathur, Melina, Lai, Joyce, Axelrod, Fumiko, Souders, Colby A, Emery, Chloe, Sato, Aaron K

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Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage libraries von Yuan, Tom Z, Garg, Pankaj, Wang, Linya, Willis, Jordan R, Kwan, Eric, Hernandez, Ana G Lujan, Tuscano, Emily, Sever, Emily N, Keane, Erica, Soto, Cinque, Mucker, Eric M, Fouch, Mallorie E, Davidson, Edgar, Doranz, Benjamin J, Kailasan, Shweta, Aman, M Javad, Li, Haoyang, Hooper, Jay W, Saphire, Erica Ollmann, Crowe, James E, Liu, Qiang, Axelrod, Fumiko, Sato, Aaron K

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Functional GLP-1R antibodies identified from a synthetic GPCR-focused library demonstrate potent blood glucose control von Liu, Qiang, Garg, Pankaj, Hasdemir, Burcu, Wang, Linya, Tuscano, Emily, Sever, Emily, Keane, Erica, Hernandez, Ana G. Lujan, Yuan, Tom Z., Kwan, Eric, Lai, Joyce, Szot, Greg, Paruthiyil, Sreenivasan, Axelrod, Fumiko, K. Sato, Aaron

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RF1 attenuation enables efficient non-natural amino acid incorporation for production of homogeneous antibody drug conjugates von Yin, Gang, Stephenson, Heather T., Yang, Junhao, Li, Xiaofan, Armstrong, Stephanie M., Heibeck, Tyler H., Tran, Cuong, Masikat, Mary Rose, Zhou, Sihong, Stafford, Ryan L., Yam, Alice Y., Lee, John, Steiner, Alexander R., Gill, Avinash, Penta, Kalyani, Pollitt, Sonia, Baliga, Ramesh, Murray, Christopher J., Thanos, Christopher D., McEvoy, Leslie M., Sato, Aaron K., Hallam, Trevor J.

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Post-Exposure Protection in Mice against Sudan Virus by a Two Antibody Cocktail von Froude, Jeffrey W, Herbert, Andrew S, Pelat, Thibaut, Miethe, Sebastian, Zak, Samantha E, Brannan, Jennifer M, Bakken, Russell R, Steiner, Alexander R, Yin, Gang, Hallam, Trevor J, Sato, Aaron K, Hust, Michael, Thullier, Philippe, Dye, John M

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Engineering toward a bacterial "endoplasmic reticulum" for the rapid expression of immunoglobulin proteins von Groff, Dan, Armstrong, Stephanie, Rivers, Patrick J, Zhang, Juan, Yang, Junhao, Green, Evan, Rozzelle, James, Liang, Shengwen, Kittle, Joseph D, Steiner, Alexander R, Baliga, Ramesh, Thanos, Christopher D, Hallam, Trevor J, Sato, Aaron K, Yam, Alice Y

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Therapeutic peptides: technological advances driving peptides into development von Sato, Aaron K, Viswanathan, Malini, Kent, Rachel B, Wood, Clive R

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Methods to Make Homogenous Antibody Drug Conjugates von Kline, Toni, Steiner, Alexander R., Penta, Kalyani, Sato, Aaron K., Hallam, Trevor J., Yin, Gang

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Discovery of Fully Human Anti-MET Monoclonal Antibodies with Antitumor Activity against Colon Cancer Tumor Models In Vivo von van der Horst, Edward Htun, Chinn, Lawrence, Wang, Min, Velilla, Timothy, Tran, Hoang, Madrona, Yarrow, Lam, Andrew, Ji, May, Hoey, Timothy C., Sato, Aaron K.

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Discovery of STRO-002, a Novel Homogeneous ADC Targeting Folate Receptor Alpha, for the Treatment of Ovarian and Endometrial Cancers von Li, Xiaofan, Zhou, Sihong, Abrahams, Cristina L, Krimm, Stellanie, Smith, Jennifer, Bajjuri, Krishna, Stephenson, Heather T, Henningsen, Robert, Hanson, Jeffrey, Heibeck, Tyler H, Calarese, Daniel, Tran, Cuong, Yin, Gang, Stafford, Ryan L, Yam, Alice Y, Kline, Toni, De Almeida, Venita I, Sato, Aaron K, Lupher, Mark, Bedard, Kristin, Hallam, Trevor J

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Extracellular Antigen Processing and Presentation by Immature Dendritic Cells von Santambrogio, Laura, Sato, Aaron K., Carven, Gregory J., Belyanskaya, Svetlana L., Strominger, Jack L., Stern, Lawrence J.

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Malaria Derived Glycosylphosphatidylinositol Anchor Enhances Anti-Pfs25 Functional Antibodies That Block Malaria Transmission von Kapoor, Neeraj, Vanjak, Ivana, Rozzelle, James, Berges, Aym, Chan, Wei, Yin, Gang, Tran, Cuong, Sato, Aaron K, Steiner, Alexander R, Pham, Thao P, Birkett, Ashley J, Long, Carole A, Fairman, Jeff, Miura, Kazutoyo

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Optimization of a glucagon-like peptide 1 receptor antagonist antibody for treatment of hyperinsulinism von Peterson, Sean M, Juliana, Christine A, Hu, Cameron F, Chai, Jinghua, Holliday, Carson, Chan, Kara Y, Lujan Hernandez, Ana G, Challocombe, Zoe, Wang, Linya, Han, Zhen, Haas, Nikhil, Stafford, Ryan, Axelrod, Fumiko, Yuan, Tom Z, De Leόn, Diva D, Sato, Aaron K

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A simplified and robust protocol for immunoglobulin expression in Escherichia coli cell-free protein synthesis systems von Cai, Qi, Hanson, Jeffrey A., Steiner, Alexander R., Tran, Cuong, Masikat, Mary Rose, Chen, Rishard, Zawada, James F., Sato, Aaron K., Hallam, Trevor J., Yin, Gang

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Toward a Ferrous Iron-Cleavable Linker for Antibody–Drug Conjugates von Spangler, Benjamin, Kline, Toni, Hanson, Jeffrey, Li, Xiaofan, Zhou, Sihong, Wells, James A, Sato, Aaron K, Renslo, Adam R

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Abundant Empty Class II MHC Molecules on the Surface of Immature Dendritic Cells von Santambrogio, Laura, Sato, Aaron K., Fischer, Falko R., Dorf, Martin E., Stern, Lawrence J.

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Targeted Drug Delivery with an Integrin-Binding Knottin-Fc-MMAF Conjugate Produced by Cell-Free Protein Synthesis von Currier, Nicolas V, Ackerman, Shelley E, Kintzing, James R, Chen, Rishard, Filsinger Interrante, Maria, Steiner, Alexander, Sato, Aaron K, Cochran, Jennifer R

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Phage display-derived peptides as therapeutic alternatives to antibodies von Ladner, Robert C, Sato, Aaron K, Gorzelany, Jennifer, de Souza, Mark

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Identification of an ADAMTS-4 Cleavage Motif Using Phage Display Leads to the Development of Fluorogenic Peptide Substrates and Reveals Matrilin-3 as a Novel Substrate von Hills, Robert, Mazzarella, Richard, Fok, Kam, Liu, Min, Nemirovskiy, Olga, Leone, Joseph, Zack, Marc D., Arner, Elizabeth C., Viswanathan, Malini, Abujoub, Aida, Muruganandam, Arumugam, Sexton, Daniel J., Bassill, Gary J., Sato, Aaron K., Malfait, Anne-Marie, Tortorella, Micky D.

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