Bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with human papillomavirus-associated malignancies von Strauss, Julius, Gatti-Mays, Margaret E, Cho, Byoung Chul, Hill, Andrew, Salas, Sébastien, McClay, Edward, Redman, Jason M, Sater, Houssein A, Donahue, Renee N, Jochems, Caroline, Lamping, Elizabeth, Burmeister, Andrea, Marté, Jennifer L, Cordes, Lisa M, Bilusic, Marijo, Karzai, Fatima, Ojalvo, Laureen S, Jehl, Genevieve, Rolfe, P Alexander, Hinrichs, Christian S, Madan, Ravi A, Schlom, Jeffrey, Gulley, James L

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Multiplex computational pathology for treatment response predication von Lu, Ming Y., Sater, Houssein A., Mahmood, Faisal

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Multiplex computational pathology for treatment response prediction von Lu, Ming Y., Sater, Houssein A., Mahmood, Faisal

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Abstract B049: Radiogenomic profiling of prostate tumors prior to external beam radiotherapy (EBRT) converges on a transcriptomic signature of TGF-beta activity driving tumor recur... von Sowalsky, Adam G., Ku, Anson T., Shankavaram, Uma, Trostel, Shana Y., Sater, Houssein A., Harmon, Stephanie A., Carrabba, Nicole V., Liu, Yang, Stoyanova, Radka, Davicioni, Elai, Pollack, Alan, Turkbey, Baris, Citrin, Deborah E.

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Nascent prostate cancer heterogeneity drives evolution and resistance to intense hormonal therapy von Wilkinson, Scott, Ye, Huihui, Karzai, Fatima, Harmon, Stephanie A., Terrigino, Nicholas T., VanderWelle, David J., Bright, John R., Atway, Rayann, Trostel, Shana Y., Carrabba, Nicole V., Whitlock, Nichelle C., Walker, Stephanie M., Lis, Rosina T., Sater, Houssein A., Capaldo, Brian J., Madan, Ravi A., Gulley, James L., Chun, Guinevere, Merino, Maria J., Pinto, Peter A., Salles, Daniela C., Kaur, Harsimar B., Lotan, Tamara L., Venzon, David J., Choyke, Peter L., Turkbey, Baris, Dahut, William L., Sowalsky, Adam G.

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Tumor control via targeting PD-L1 with chimeric antigen receptor modified NK cells von Robbins, Yvette, Greene, Sarah, Friedman, Jay, Clavijo, Paul E., Van Waes, Carter, Fabian, Kellsye P., Padget, Michelle R., Sater, Houssein Abdul, Lee, John H., Soon-Shiong, Patrick, Gulley, James, Schlom, Jeffrey, Hodge, James W., Allen, Clint T.

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If we build it they will come: targeting the immune response to breast cancer von Gatti-Mays, Margaret E., Balko, Justin M., Gameiro, Sofia R., Bear, Harry D., Prabhakaran, Sangeetha, Fukui, Jami, Disis, Mary L., Nanda, Rita, Gulley, James L., Kalinsky, Kevin, Abdul Sater, Houssein, Sparano, Joseph A., Cescon, David, Page, David B., McArthur, Heather, Adams, Sylvia, Mittendorf, Elizabeth A.

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Combining a β3 adrenergic receptor agonist with alpha‐lipoic acid reduces inflammation in male mice with diet‐induced obesity von Abdul Sater, Zahraa, Cero, Cheryl, Pierce, Anne E., Lea, Hannah J., Abdul Sater, Houssein, Zhu, Kenneth Y., Liu, Naili, Ma, Yinyan, Gavrilova, Oksana, Cypess, Aaron M.

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Phase I Trial of a Modified Vaccinia Ankara Priming Vaccine Followed by a Fowlpox Virus Boosting Vaccine Modified to Express Brachyury and Costimulatory Molecules in Advanced Solid... von Collins, Julie M., Donahue, Renee N., Tsai, Yo‐Ting, Manu, Michell, Palena, Claudia, Gatti‐Mays, Margaret E., Marté, Jennifer L., Madan, Ravi A., Karzai, Fatima, Heery, Christopher R., Strauss, Julius, Abdul‐Sater, Houssein, Cordes, Lisa, Schlom, Jeffrey, Gulley, James L., Bilusic, Marijo

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Nascent Prostate Cancer Heterogeneity Drives Evolution and Resistance to Intense Hormonal Therapy von Wilkinson, Scott, Ye, Huihui, Karzai, Fatima, Harmon, Stephanie A., Terrigino, Nicholas T., VanderWeele, David J., Bright, John R., Atway, Rayann, Trostel, Shana Y., Carrabba, Nicole V., Whitlock, Nichelle C., Walker, Stephanie M., Lis, Rosina T., Abdul Sater, Houssein, Capaldo, Brian J., Madan, Ravi A., Gulley, James L., Chun, Guinevere, Merino, Maria J., Pinto, Peter A., Salles, Daniela C., Kaur, Harsimar B., Lotan, Tamara L., Venzon, David J., Choyke, Peter L., Turkbey, Baris, Dahut, William L., Sowalsky, Adam G.

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Chimeric antigen receptor engineered NK cellular immunotherapy overcomes the selection of T-cell escape variant cancer cells von Lee, Maxwell Y, Robbins, Yvette, Sievers, Cem, Friedman, Jay, Abdul Sater, Houssein, Clavijo, Paul E, Judd, Nancy, Tsong, Edward, Silvin, Chris, Soon-Shiong, Patrick, Padget, Michelle R, Schlom, Jeffrey, Hodge, James, Hinrichs, Christian, Allen, Clint

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Phase I study of a multitargeted recombinant Ad5 PSA/MUC-1/brachyury-based immunotherapy vaccine in patients with metastatic castration-resistant prostate cancer (mCRPC) von Bilusic, Marijo, McMahon, Sheri, Madan, Ravi A, Karzai, Fatima, Tsai, Yo-Ting, Donahue, Renee N, Palena, Claudia, Jochems, Caroline, Marté, Jennifer L, Floudas, Charalampos, Strauss, Julius, Redman, Jason, Abdul Sater, Houssein, Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Schlom, Jeffrey, Gulley, James L

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Neoadjuvant PROSTVAC prior to radical prostatectomy enhances T-cell infiltration into the tumor immune microenvironment in men with prostate cancer von Abdul Sater, Houssein, Marté, Jennifer L, Donahue, Renee N, Walter-Rodriguez, Beatriz, Heery, Christopher R, Steinberg, Seth M, Cordes, Lisa M, Chun, Guinevere, Karzai, Fatima, Bilusic, Marijo, Harmon, Stephanie A, Turkbey, Ismail Baris, Choyke, Peter L, Schlom, Jeffrey, Dahut, William L, Madan, Ravi A, Pinto, Peter A, Gulley, James L

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A Randomized Phase II Trial of mFOLFOX6 + Bevacizumab Alone or with AdCEA Vaccine + Avelumab Immunotherapy for Untreated Metastatic Colorectal Cancer von Redman, Jason M, Tsai, Yo-Ting, Weinberg, Benjamin A, Donahue, Renee N, Gandhy, Shruti, Gatti-Mays, Margaret E, Abdul Sater, Houssein, Bilusic, Marijo, Cordes, Lisa M, Steinberg, Seth M, Marte, Jennifer L, Jochems, Caroline, Kim, Sunnie S, Marshall, John L, McMahon, Sheri, Redmond, Erica, Schlom, Jeffrey, Gulley, James L, Strauss, Julius

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The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis von Eisa, Nada H., Jilani, Yasmeen, Kainth, Kashish, Redd, Priscilla, Lu, Su, Bougrine, Oulia, Abdul Sater, Houssein, Patwardhan, Chaitanya A., Shull, Austin, Shi, Huidong, Liu, Kebin, Elsherbiny, Nehal M., Eissa, Laila A., El-Shishtawy, Mamdouh M., Horuzsko, Anatolij, Bollag, Roni, Maihle, Nita, Roig, Joan, Korkaya, Hasan, Cowell, John K., Chadli, Ahmed

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Efficacy, safety, and biomarker analyses of bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with advanced non-small cell lung cancer von Rajan, Arun, Abdul Sater, Houssein, Rahma, Osama, Agajanian, Richy, Lassoued, Wiem, Marté, Jennifer L, Tsai, Yo-Ting, Donahue, Renee N, Lamping, Elizabeth, Bailey, Shania, Weisman, Andrew, Walter-Rodriguez, Beatriz, Ito, Rena, Vugmeyster, Yulia, Sato, Masashi, Machl, Andreas, Schlom, Jeffrey, Gulley, James L

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Dual PD-L1 and TGF-b blockade in patients with recurrent respiratory papillomatosis von Robbins, Yvette, Friedman, Jay, Clavijo, Paul E, Sievers, Cem, Bai, Ke, Donahue, Renee N, Schlom, Jeffrey, Sinkoe, Andrew, Abdul Sater, Houssein, Gulley, James L, Norberg, Scott, Hinrichs, Christian S, Allen, Clint

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Abstract 2263: Complete remission of a patient with Merkel cell carcinoma treated with durvalumab von Sabbagh, Saad, Dominguez, Barbara, Sater, Houssein Abdul

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Therapy of Established Tumors with Rationally Designed Multiple Agents Targeting Diverse Immune-Tumor Interactions: Engage, Expand, Enable von Fabian, Kellsye P., Malamas, Anthony S., Padget, Michelle R., Solocinski, Kristen, Wolfson, Benjamin, Fujii, Rika, Sater, Houssein Abdul, Schlom, Jeffrey, Hodge, James W.

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Breast cancer molecular subtypes association with clinical outcomes and race von Sadek, Ramses F., Zhang, Li fang, Abdul Sater, Houssein Talal

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