Early‐onset colorectal cancer in young individuals von Mauri, Gianluca, Sartore‐Bianchi, Andrea, Russo, Antonio‐Giampiero, Marsoni, Silvia, Bardelli, Alberto, Siena, Salvatore

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Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer von Russo, Mariangela, Misale, Sandra, Wei, Ge, Siravegna, Giulia, Crisafulli, Giovanni, Lazzari, Luca, Corti, Giorgio, Rospo, Giuseppe, Novara, Luca, Mussolin, Benedetta, Bartolini, Alice, Cam, Nicholas, Patel, Roopal, Yan, Shunqi, Shoemaker, Robert, Wild, Robert, Di Nicolantonio, Federica, Bianchi, Andrea Sartore, Li, Gang, Siena, Salvatore, Bardelli, Alberto

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Radiomics predicts response of individual HER2‐amplified colorectal cancer liver metastases in patients treated with HER2‐targeted therapy von Giannini, Valentina, Rosati, Samanta, Defeudis, Arianna, Balestra, Gabriella, Vassallo, Lorenzo, Cappello, Giovanni, Mazzetti, Simone, De Mattia, Cristina, Rizzetto, Francesco, Torresin, Alberto, Sartore‐Bianchi, Andrea, Siena, Salvatore, Vanzulli, Angelo, Leone, Francesco, Zagonel, Vittorina, Marsoni, Silvia, Regge, Daniele

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Mechanisms of Immune Escape and Resistance to Checkpoint Inhibitor Therapies in Mismatch Repair Deficient Metastatic Colorectal Cancers von Amodio, Vito, Mauri, Gianluca, Reilly, Nicole M., Sartore-Bianchi, Andrea, Siena, Salvatore, Bardelli, Alberto, Germano, Giovanni

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Early onset metastatic colorectal cancer in patients receiving panitumumab‐based upfront strategy: Overall and sex‐specific outcomes in the Valentino trial von Raimondi, Alessandra, Randon, Giovanni, Prisciandaro, Michele, Pagani, Filippo, Lonardi, Sara, Antoniotti, Carlotta, Bozzarelli, Silvia, Sartore‐Bianchi, Andrea, Tampellini, Marco, Fanchini, Laura, Murialdo, Roberto, Clavarezza, Matteo, Zaniboni, Alberto, Berenato, Rosa, Ratti, Margherita, Petrelli, Fausto, Antonuzzo, Lorenzo, Giordano, Monica, Rossi, Alessandro, Di Bartolomeo, Maria, Di Maio, Massimo, Pietrantonio, Filippo, Morano, Federica

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KRAS gene amplification in colorectal cancer and impact on response to EGFR‐targeted therapy von Valtorta, Emanuele, Misale, Sandra, Sartore‐Bianchi, Andrea, Nagtegaal, Iris D., Paraf, François, Lauricella, Calogero, Dimartino, Valentina, Hobor, Sebastijan, Jacobs, Bart, Ercolani, Cristiana, Lamba, Simona, Scala, Elisa, Veronese, Silvio, Laurent‐Puig, Pierre, Siena, Salvatore, Tejpar, Sabine, Mottolese, Marcella, Punt, Cornelis J.A., Gambacorta, Marcello, Bardelli, Alberto, Nicolantonio, Federica

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Resistance to anti-EGFR therapy in colorectal cancer: from heterogeneity to convergent evolution von Misale, Sandra, Di Nicolantonio, Federica, Sartore-Bianchi, Andrea, Siena, Salvatore, Bardelli, Alberto

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Adaptive mutability of colorectal cancers in response to targeted therapies von Russo, Mariangela, Crisafulli, Giovanni, Sogari, Alberto, Reilly, Nicole M, Arena, Sabrina, Lamba, Simona, Bartolini, Alice, Amodio, Vito, Magrì, Alessandro, Novara, Luca, Sarotto, Ivana, Nagel, Zachary D, Piett, Cortt G, Amatu, Alessio, Sartore-Bianchi, Andrea, Siena, Salvatore, Bertotti, Andrea, Trusolino, Livio, Corigliano, Mattia, Gherardi, Marco, Lagomarsino, Marco Cosentino, Di Nicolantonio, Federica, Bardelli, Alberto

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Biomarkers Predicting Clinical Outcome of Epidermal Growth Factor Receptor–Targeted Therapy in Metastatic Colorectal Cancer von Siena, Salvatore, Sartore-Bianchi, Andrea, Di Nicolantonio, Federica, Balfour, Julia, Bardelli, Alberto

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Plasma HER2 ( ERBB2 ) Copy Number Predicts Response to HER2-targeted Therapy in Metastatic Colorectal Cancer von Siravegna, Giulia, Sartore-Bianchi, Andrea, Nagy, Rebecca J, Raghav, Kanwal, Odegaard, Justin I, Lanman, Richard B, Trusolino, Livio, Marsoni, Silvia, Siena, Salvatore, Bardelli, Alberto

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Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept,... von Sartore-Bianchi, Andrea, MD, Trusolino, Livio, MD, Martino, Cosimo, PhD, Bencardino, Katia, MD, Lonardi, Sara, MD, Bergamo, Francesca, MD, Zagonel, Vittorina, MD, Leone, Francesco, MD, Depetris, Ilaria, MD, Martinelli, Erika, MD, Troiani, Teresa, MD, Ciardiello, Fortunato, Prof, Racca, Patrizia, MD, Bertotti, Andrea, MD, Siravegna, Giulia, MSc, Torri, Valter, MD, Amatu, Alessio, MD, Ghezzi, Silvia, MSc, Marrapese, Giovanna, PhD, Palmeri, Laura, MD, Valtorta, Emanuele, PhD, Cassingena, Andrea, MSc, Lauricella, Calogero, PhD, Vanzulli, Angelo, MD, Regge, Daniele, MD, Veronese, Silvio, MSc, Comoglio, Paolo M, Prof, Bardelli, Alberto, PhD, Marsoni, Silvia, Dr, Siena, Salvatore, Prof

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Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer von Misale, Sandra, Yaeger, Rona, Hobor, Sebastijan, Scala, Elisa, Janakiraman, Manickam, Liska, David, Valtorta, Emanuele, Schiavo, Roberta, Buscarino, Michela, Siravegna, Giulia, Bencardino, Katia, Cercek, Andrea, Chen, Chin-Tung, Veronese, Silvio, Zanon, Carlo, Sartore-Bianchi, Andrea, Gambacorta, Marcello, Gallicchio, Margherita, Vakiani, Efsevia, Boscaro, Valentina, Medico, Enzo, Weiser, Martin, Siena, Salvatore, Di Nicolantonio, Federica, Solit, David, Bardelli, Alberto

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HER2 Positivity Predicts Unresponsiveness to EGFR‐Targeted Treatment in Metastatic Colorectal Cancer von Sartore‐Bianchi, Andrea, Amatu, Alessio, Porcu, Luca, Ghezzi, Silvia, Lonardi, Sara, Leone, Francesco, Bergamo, Francesca, Fenocchio, Elisabetta, Martinelli, Erika, Borelli, Beatrice, Tosi, Federica, Racca, Patrizia, Valtorta, Emanuele, Bonoldi, Emanuela, Martino, Cosimo, Vaghi, Caterina, Marrapese, Giovanna, Ciardiello, Fortunato, Zagonel, Vittorina, Bardelli, Alberto, Trusolino, Livio, Torri, Valter, Marsoni, Silvia, Siena, Salvatore

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Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer von Barault, Ludovic, Amatu, Alessio, Siravegna, Giulia, Ponzetti, Agostino, Moran, Sebastian, Cassingena, Andrea, Mussolin, Benedetta, Falcomatà, Chiara, Binder, Alexandra M, Cristiano, Carmen, Oddo, Daniele, Guarrera, Simonetta, Cancelliere, Carlotta, Bustreo, Sara, Bencardino, Katia, Maden, Sean, Vanzati, Alice, Zavattari, Patrizia, Matullo, Giuseppe, Truini, Mauro, Grady, William M, Racca, Patrizia, Michels, Karin B, Siena, Salvatore, Esteller, Manel, Bardelli, Alberto, Sartore-Bianchi, Andrea, Di Nicolantonio, Federica

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The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets von Medico, Enzo, Russo, Mariangela, Picco, Gabriele, Cancelliere, Carlotta, Valtorta, Emanuele, Corti, Giorgio, Buscarino, Michela, Isella, Claudio, Lamba, Simona, Martinoglio, Barbara, Veronese, Silvio, Siena, Salvatore, Sartore-Bianchi, Andrea, Beccuti, Marco, Mottolese, Marcella, Linnebacher, Michael, Cordero, Francesca, Di Nicolantonio, Federica, Bardelli, Alberto

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Wild-Type BRAF Is Required for Response to Panitumumab or Cetuximab in Metastatic Colorectal Cancer von Di Nicolantonio, Federica, Martini, Miriam, Molinari, Francesca, Sartore-Bianchi, Andrea, Arena, Sabrina, Saletti, Piercarlo, De Dosso, Sara, Mazzucchelli, Luca, Frattini, Milo, Siena, Salvatore, Bardelli, Alberto

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CDK4/6 Inhibitors in Breast Cancer Treatment: Potential Interactions with Drug, Gene, and Pathophysiological Conditions von Roncato, Rossana, Angelini, Jacopo, Pani, Arianna, Cecchin, Erika, Sartore-Bianchi, Andrea, Siena, Salvatore, De Mattia, Elena, Scaglione, Francesco, Toffoli, Giuseppe

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ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer von Pietrantonio, Filippo, Di Nicolantonio, Federica, Schrock, Alexa B, Lee, Jeeyun, Tejpar, Sabine, Sartore-Bianchi, Andrea, Hechtman, Jaclyn F, Christiansen, Jason, Novara, Luca, Tebbutt, Niall, Fucà, Giovanni, Antoniotti, Carlotta, Kim, Seung Tae, Murphy, Danielle, Berenato, Rosa, Morano, Federica, Sun, James, Min, Bosun, Stephens, Philip J, Chen, Marissa, Lazzari, Luca, Miller, Vincent A, Shoemaker, Robert, Amatu, Alessio, Milione, Massimo, Ross, Jeffrey S, Siena, Salvatore, Bardelli, Alberto, Ali, Siraj M, Falcone, Alfredo, de Braud, Filippo, Cremolini, Chiara

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Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients von Crisafulli, Giovanni, Sartore-Bianchi, Andrea, Lazzari, Luca, Pietrantonio, Filippo, Amatu, Alessio, Macagno, Marco, Barault, Ludovic, Cassingena, Andrea, Bartolini, Alice, Luraghi, Paolo, Mauri, Gianluca, Battuello, Paolo, Personeni, Nicola, Zampino, Maria Giulia, Pessei, Valeria, Vitiello, Pietro Paolo, Tosi, Federica, Idotta, Laura, Morano, Federica, Valtorta, Emanuele, Bonoldi, Emanuela, Germano, Giovanni, Di Nicolantonio, Federica, Marsoni, Silvia, Siena, Salvatore, Bardelli, Alberto

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Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies von BENVENUTI, Silvia, SARTORE-BIANCHI, Andrea, DI NICOLANTONIO, Federica, ZANON, Carlo, MORONI, Mauro, VERONESE, Silvio, SIENA, Salvatore, BARDELLI, Alberto

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