Synthesis, biological evaluation, and pharmacokinetic study of prolyl-1-piperazinylacetic acid and prolyl-4-piperidinylacetic acid derivatives as VLA-4 antagonists von Chiba, Jun, Takayama, Gensuke, Takashi, Tohru, Yokoyama, Mika, Nakayama, Atsushi, Baldwin, John J., McDonald, Edward, Moriarty, Kevin J., Sarko, Christopher R., Saionz, Kurt W., Swanson, Robert, Hussain, Zahid, Wong, Angela, Machinaga, Nobuo

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Development and Applications of a Practical Continuous Flow Microwave Cell von Wilson, Noel S., Sarko, Christopher R., Roth, Gregory P.

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Hit-to-lead studies on benzimidazole inhibitors of ITK: Discovery of a novel class of kinase inhibitors von Snow, Roger J., Abeywardane, Asitha, Campbell, Scot, Lord, John, Kashem, Mohammed A., Khine, Hnin Hnin, King, Josephine, Kowalski, Jennifer A., Pullen, Steven S., Roma, Teresa, Roth, Gregory P., Sarko, Christopher R., Wilson, Noel S., Winters, Michael P., Wolak, John P., Cywin, Charles L.

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TADDOL-Based Titanium Catalysts and Their Adducts: Understanding Asymmetric Catalysis of Diels-Alder Reactions von Haase, Cornelius, Sarko, Christopher R, DiMare, Marcello

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Microwave-assisted synthesis of a [3+2] cycloaddition library von Wilson, Noel S, Sarko, Christopher R, Roth, Gregory P

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Microwave-assisted synthesis of 2-aminoquinolines von Wilson, Noel S, Sarko, Christopher R, Roth, Gregory P

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BCl3- and TiCl4-Mediated Reductions of β-Hydroxy Ketones von Sarko, Christopher R, Collibee, Scott E, Knorr, Allison L, DiMare, Marcello

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Chelation-controlled protocol for the diastereoselective reduction of ketones von Sarko, Christopher R, Guch, Ian C, DiMare, Marcello

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Identified a morpholinyl-4-piperidinylacetic acid derivative as a potent oral active VLA-4 antagonist von Chiba, Jun, Machinaga, Nobuo, Takashi, Tohru, Ejima, Akio, Takayama, Gensuke, Yokoyama, Mika, Nakayama, Atsushi, Baldwin, John J., McDonald, Edward, Saionz, Kurt W., Swanson, Robert, Hussain, Zahid, Wong, Angela

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Corrigendum to “Identified a morpholinyl-4-piperidinylacetic acid derivatives as a potent oral active VLA-4 antagonist”: [Bioorg. Med. Chem. Lett. 15 (1) (2005) 41] von Chiba, Jun, Machinaga, Nobuo, Takashi, Tohru, Ejima, Akio, Takayama, Gensuke, Yokoyama, Mika, Nakayama, Atsushi, Baldwin, John J., McDonald, Edward, Moriarty, Kevin J., Sarko, Christopher R., Saionz, Kurt W., Swanson, Robert, Hussain, Zahid, Wong, Angela

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Efficient stereoselective synthesis of the epoxyacid fragment of the azinomycins von Coleman, Robert S., Sarko, Christopher R., Gittinger, Jens P.

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Timesavings Associated with Microwave-Assisted Synthesis: A Quantitative Approach von Sarko, Christopher R.

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BCl 3 - and TiCl 4 -Mediated Reductions of β-Hydroxy Ketones von Sarko, Christopher R., Collibee, Scott E., Knorr, Allison L., DiMare, Marcello

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ChemInform Abstract: Microwave-Assisted Synthesis of 2-Aminoquinolines von Wilson, Noel S., Sarko, Christopher R., Roth, Gregory P.

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ChemInform Abstract: Microwave-Assisted Synthesis of a [3 + 2] Cycloaddition Library von Wilson, Noel S., Sarko, Christopher R., Roth, Gregory P.

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VLA-4 inhibitor compounds von MCDONALD EDWARD, MACHINAGA NOBUO, IIMURA SHIN, YONEDA YOSHIYUKI, SARKO CHRISTOPHER R, NAKAYAMA ATSUSHI, BALDWIN JOHN J, MORIARTY KEVIN J, CHIBA JUN

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BENZIMIDAZOLES USEFUL AS PROTEIN KINASE INHIBITORS von CHARLES L. CYWIN, JINBO LEE, NOEL S. WILSON, ROGER JOHN SNOW, GREGORY P. ROUTH, STEVEN S. PULLEN, CHRISTOPHER R. SARKO

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Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncompl... von Taft, Benjamin R, Yokokawa, Fumiaki, Kirrane, Tom, Mata, Anne-Catherine, Huang, Richard, Blaquiere, Nicole, Waldron, Grace, Zou, Bin, Simon, Oliver, Vankadara, Subramanyam, Chan, Wai Ling, Ding, Mei, Sim, Sandra, Straimer, Judith, Guiguemde, Armand, Lakshminarayana, Suresh B, Jain, Jay Prakash, Bodenreider, Christophe, Thompson, Christopher, Lanshoeft, Christian, Shu, Wei, Fang, Eric, Qumber, Jafri, Chan, Katherine, Pei, Luying, Chen, Yen-Liang, Schulz, Hanna, Lim, Jessie, Abas, Siti Nurdiana, Ang, Xiaoman, Liu, Yugang, Angulo-Barturen, Iñigo, Jiménez-Díaz, María Belén, Gamo, Francisco Javier, Crespo-Fernandez, Benigno, Rosenthal, Philip J, Cooper, Roland A, Tumwebaze, Patrick, Aguiar, Anna Caroline Campos, Campo, Brice, Campbell, Simon, Wagner, Jürgen, Diagana, Thierry T, Sarko, Christopher

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Discovery and Optimization of p38 Inhibitors via Computer-Assisted Drug Design von Goldberg, Daniel R, Hao, Ming-Hong, Qian, Kevin C, Swinamer, Alan D, Gao, Donghong A, Xiong, Zhaoming, Sarko, Chris, Berry, Angela, Lord, John, Magolda, Ronald L, Fadra, Tazmeen, Kroe, Rachel R, Kukulka, Alison, Madwed, Jeffrey B, Martin, Leslie, Pargellis, Christopher, Skow, Donna, Song, Jinhua J, Tan, Zhulin, Torcellini, Carol A, Zimmitti, Clare S, Yee, Nathan K, Moss, Neil

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Discovery and design of benzimidazolone based inhibitors of p38 MAP kinase von Hammach, Abdelhakim, Barbosa, Antonio, Gaenzler, Faith Corbo, Fadra, Tazmeen, Goldberg, Daniel, Hao, Ming-Hong, Kroe, Rachel R., Liu, Pingrong, Qian, Kevin C., Ralph, Mark, Sarko, Christopher, Soleymanzadeh, Fariba, Moss, Neil

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