Timed action of IL-27 protects from immunopathology while preserving defense in influenza von Liu, Francesca Diane M, Kenngott, Elisabeth E, Schröter, Micha F, Kühl, Anja, Jennrich, Silke, Watzlawick, Ralf, Hoffmann, Ute, Wolff, Thorsten, Norley, Stephen, Scheffold, Alexander, Stumhofer, Jason S, Saris, Christiaan J M, Schwab, Jan M, Hunter, Christopher A, Debes, Gudrun F, Hamann, Alf

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IL-27 Limits IL-2 Production during Th1 Differentiation von Villarino, Alejandro V, Stumhofer, Jason S, Saris, Christiaan J. M, Kastelein, Robert A, de Sauvage, Frederic J, Hunter, Christopher A

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Interleukin 27 inhibits atherosclerosis via immunoregulation of macrophages in mice von Hirase, Tetsuaki, Hara, Hiromitsu, Miyazaki, Yoshiyuki, Ide, Noriko, Nishimoto-Hazuku, Ai, Fujimoto, Hirokazu, Saris, Christiaan J M, Yoshida, Hiroki, Node, Koichi

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The IL-27 Receptor (WSX-1) Is an Inhibitor of Innate and Adaptive Elements of Type 2 Immunity von Artis, David, Villarino, Alejandro, Silverman, Michael, He, Weimian, Thornton, Elizabeth M, Mu, Sharon, Summer, Shamin, Covey, Todd M, Huang, Elaine, Yoshida, Hiroki, Koretzky, Gary, Goldschmidt, Michael, Wu, Gary D, de Sauvage, Fred, Miller, Hugh R. P, Saris, Christiaan J. M, Scott, Phillip, Hunter, Christopher A

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Positive and Negative Regulation of the IL-27 Receptor during Lymphoid Cell Activation von Villarino, Alejandro V, Larkin, Joseph, III, Saris, Christiaan J. M, Caton, Andrew J, Lucas, Sophie, Wong, Terence, de Sauvage, Frederic J, Hunter, Christopher A

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A role for IL-27p28 as an antagonist of gp130-mediated signaling von Hunter, Christopher A, Stumhofer, Jason S, Tait, Elia D, III, William J Quinn, Hosken, Nancy, Spudy, Björn, Goenka, Radhika, Fielding, Ceri A, O'Hara, Aisling C, Chen, Yi, Jones, Michael L, Saris, Christiaan J M, Rose-John, Stefan, Cua, Daniel J, Jones, Simon A, Elloso, Merle M, Grötzinger, Joachim, Cancro, Michael P, Levin, Steven D

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IL-27R deficiency delays the onset of colitis and protects from helminth-induced pathology in a model of chronic IBD von Villarino, Alejandro V., Artis, David, Bezbradica, Jelena S., Miller, Omer, Saris, Christiaan J. M., Joyce, Sebastian, Hunter, Christopher A.

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A novel role for IL-27 in mediating the survival of activated mouse CD4 T lymphocytes von Kim, Gisen, Shinnakasu, Ryo, Saris, Christiaan J M, Cheroutre, Hilde, Kronenberg, Mitchell

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Interleukin-27 Receptor Limits Atherosclerosis in Ldlr−/− Mice von Koltsova, Ekaterina K, Kim, Gisen, Lloyd, Kathleen M, Saris, Christiaan J.M, von Vietinghoff, Sibylle, Kronenberg, Mitchell, Ley, Klaus

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Discovery of Pyridazinopyridinones as Potent and Selective p38 Mitogen-Activated Protein Kinase Inhibitors von Wu, Bin, Wang, Hui-Ling, Pettus, Liping, Wurz, Ryan P, Doherty, Elizabeth M, Henkle, Bradley, McBride, Helen J, Saris, Christiaan J. M, Wong, Lu Min, Plant, Matthew H, Sherman, Lisa, Lee, Matthew R, Hsieh, Faye, Tasker, Andrew S

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IL-27 Inhibits Hyperglycemia and Pancreatic Islet Inflammation Induced by Streptozotocin in Mice von Fujimoto, Hirokazu, Hirase, Tetsuaki, Miyazaki, Yoshiyuki, Hara, Hiromitsu, Ide-Iwata, Noriko, Nishimoto-Hazuku, Ai, Saris, Christiaan J.M, Yoshida, Hiroki, Node, Koichi

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Independent and interdependent immunoregulatory effects of IL-27, IFN-β, and IL-10 in the suppression of human Th17 cells and murine experimental autoimmune encephalomyelitis von Fitzgerald, Denise C, Fonseca-Kelly, Zoë, Cullimore, Melissa L, Safabakhsh, Pegah, Saris, Christiaan J M, Zhang, Guang-Xian, Rostami, Abdolmohamad

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IL-27 Regulates Homeostasis of the Intestinal CD4+ Effector T Cell Pool and Limits Intestinal Inflammation in a Murine Model of Colitis von Troy, Amy E, Zaph, Colby, Du, Yurong, Taylor, Betsy C, Guild, Katherine J, Hunter, Christopher A, Saris, Christiaan J. M, Artis, David

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Identification of triazolopyridazinones as potent p38α inhibitors von Herberich, Brad, Jackson, Claire, Wurz, Ryan P., Pettus, Liping H., Sherman, Lisa, Liu, Qiurong, Henkle, Bradley, Saris, Christiaan J.M., Wong, Lu Min, Chmait, Samer, Lee, Matthew R., Mohr, Christopher, Hsieh, Faye, Tasker, Andrew S.

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Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells von Fonseca-Kelly, Zoë, Yu, Shuo, Fitzgerald, Denise C, Gran, Bruno, El-Behi, Mohamed, Saris, Christiaan J M, Rostami, Abdolmohamad, Li, Hongmei, Zhang, Guang-Xian, Ciric, Bogoljub

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Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10 von Hunter, Christopher A, O'Shea, John J, Stumhofer, Jason S, Saris, Christiaan J M, Turka, Laurence A, Harris, Tajie H, Porrett, Paige M, Ernst, Matthias, Laurence, Arian, Silver, Jonathan S

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Suppressor of cytokine signaling 3 regulates CD8 T-cell proliferation by inhibition of interleukins 6 and 27 von Brender, Christine, Tannahill, Gillian M., Jenkins, Brendan J., Fletcher, Joel, Columbus, Ruth, Saris, Christiaan J.M., Ernst, Matthias, Nicola, Nicos A., Hilton, Douglas J., Alexander, Warren S., Starr, Robyn

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Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system von Hunter, Christopher A, Stumhofer, Jason S, Laurence, Arian, Wilson, Emma H, Huang, Elaine, Tato, Cristina M, Johnson, Leanne M, Villarino, Alejandro V, Huang, Qiulong, Yoshimura, Akihiko, Sehy, David, Saris, Christiaan J M, O'Shea, John J, Hennighausen, Lothar, Ernst, Matthias

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The WSX-1 pathway restrains intestinal T-cell immunity von McAleer, Jeremy P, Saris, Christiaan J M, Vella, Anthony T

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Part 1: Structure–Activity Relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38α mitogen-activated protein kinase von Wurz, Ryan P., Pettus, Liping H., Xu, Shimin, Henkle, Bradley, Sherman, Lisa, Plant, Matthew, Miner, Kent, McBride, Helen, Wong, Lu Min, Saris, Christiaan J.M., Lee, Matthew R., Chmait, Samer, Mohr, Christopher, Hsieh, Faye, Tasker, Andrew S.

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