SOCS1 cooperates with FLT3-ITD in the development of myeloproliferative disease by promoting the escape from external cytokine control von Reddy, Pavankumar N.G., Sargin, Bülent, Choudhary, Chunaram, Stein, Stefan, Grez, Manuel, Müller-Tidow, Carsten, Berdel, Wolfgang E., Serve, Hubert, Brandts, Christian H.

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S100A2 Induces Metastasis in Non–Small Cell Lung Cancer von Bulk, Etmar, Sargin, Bülent, Krug, Utz, Hascher, Antje, Jun, Yu, Knop, Markus, Kerkhoff, Claus, Gerke, Volker, Liersch, Ruediger, Mesters, Rolf M, Hotfilder, Marc, Marra, Alessandro, Koschmieder, Steffen, Dugas, Martin, Berdel, Wolfgang E, Serve, Hubert, Müller-Tidow, Carsten

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Constitutive activation of akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation von BRANDTS, Christian H, SARGIN, Bülent, BERDEL, Wolfgang E, SERVE, Hubert, RODE, Miriam, BIERMANN, Christoph, LINDTNER, Beate, SCHWÄBLE, Joachim, BUERGER, Horst, MÜLLER-TIDOW, Carsten, CHOUDHARY, Chunaram, MCMAHON, Martin

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Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations von Mizuki, Masao, Schwäble, Joachim, Steur, Claudia, Choudhary, Chunaram, Agrawal, Shuchi, Sargin, Bülent, Steffen, Björn, Matsumura, Itaru, Kanakura, Yuzuru, Böhmer, Frank D., Müller-Tidow, Carsten, Berdel, Wolfgang E., Serve, Hubert

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Activation mechanisms of STAT5 by oncogenic Flt3-ITD von Choudhary, Chunaram, Brandts, Christian, Schwable, Joachim, Tickenbrock, Lara, Sargin, Bülent, Ueker, Andrea, Böhmer, Frank-D., Berdel, Wolfgang E., Müller-Tidow, Carsten, Serve, Hubert

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AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations von Choudhary, Chunaram, Schwäble, Joachim, Brandts, Christian, Tickenbrock, Lara, Sargin, Bülent, Kindler, Thomas, Fischer, Thomas, Berdel, Wolfgang E., Müller-Tidow, Carsten, Serve, Hubert

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Flt3-dependent transformation by inactivating c-Cbl mutations in AML von Sargin, Bülent, Choudhary, Chunaram, Crosetto, Nicola, Schmidt, Mirko H.H., Grundler, Rebekka, Rensinghoff, Marion, Thiessen, Christine, Tickenbrock, Lara, Schwäble, Joachim, Brandts, Christian, August, Benjamin, Koschmieder, Steffen, Bandi, Srinivasa Rao, Duyster, Justus, Berdel, Wolfgang E., Müller-Tidow, Carsten, Dikic, Ivan, Serve, Hubert

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Adjuvant Therapy with Small Hairpin RNA Interference Prevents Non-Small Cell Lung Cancer Metastasis Development in Mice von BULK, Etmar, HASCHER, Antje, SERVE, Hubert, MÜLLER-TIDOW, Carsten, LIERSCH, Ruediger, MESTERS, Rolf M, DIEDERICHS, Sven, SARGIN, Biilent, GERKE, Volker, HOTFILDER, Marc, VORMOOR, Josef, BERDEL, Wolfgang E

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Translocation Products in Acute Myeloid Leukemia Activate the Wnt Signaling Pathway in Hematopoietic Cells von Müller-Tidow, Carsten, Steffen, Björn, Cauvet, Thomas, Tickenbrock, Lara, Ji, Ping, Diederichs, Sven, Sargin, Bülent, Köhler, Gabriele, Stelljes, Matthias, Puccetti, Elena, Ruthardt, Martin, deVos, Sven, Hiebert, Scott W, Koeffler, H Phillip, Berdel, Wolfgang E, Serve, Hubert

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CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational up-regulation of p42 CCAAT enhancer–binding protein alpha von Koschmieder, Steffen, D'Alò, Francesco, Radomska, Hanna, Schöneich, Christine, Chang, Ji Suk, Konopleva, Marina, Kobayashi, Susumu, Levantini, Elena, Suh, Nanjoo, Di Ruscio, Annalisa, Voso, Maria Teresa, Watt, Julie C., Santhanam, Ramasamy, Sargin, Bülent, Kantarjian, Hagop, Andreeff, Michael, Sporn, Michael B., Perrotti, Danilo, Berdel, Wolfgang E., Müller-Tidow, Carsten, Serve, Hubert, Tenen, Daniel G.

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E3 ligase–defective Cbl mutants lead to a generalized mastocytosis and myeloproliferative disease von Bandi, Srinivasa Rao, Brandts, Christian, Rensinghoff, Marion, Grundler, Rebekka, Tickenbrock, Lara, Köhler, Gabriele, Duyster, Justus, Berdel, Wolfgang E., Müller-Tidow, Carsten, Serve, Hubert, on behalf of the Study Alliance Leukemias, Sargin, Bülent

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Flt3 tandem duplication mutations cooperate with Wnt signaling in leukemic signal transduction von Tickenbrock, Lara, Schwäble, Joachim, Wiedehage, Markus, Steffen, Björn, Sargin, Bülent, Choudhary, Chunaram, Brandts, Christian, Berdel, Wolfgang E., Müller-Tidow, Carsten, Serve, Hubert

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Wnt signaling regulates transendothelial migration of monocytes von Tickenbrock, Lara, Schwäble, Joachim, Strey, Anke, Sargin, Bülent, Hehn, Sina, Baas, Marion, Choudhary, Chunaram, Gerke, Volker, Berdel, Wolfgang E., Müller‐Tidow, Carsten, Serve, Hubert

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RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation von Schwäble, Joachim, Choudhary, Chunaram, Thiede, Christian, Tickenbrock, Lara, Sargin, Bülent, Steur, Claudia, Rehage, Maike, Rudat, Annika, Brandts, Christian, Berdel, Wolfgang E., Müller-Tidow, Carsten, Serve, Hubert

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SOCS1 Cooperates with FLT3-ITD In the Development of Myeloproliferative Disease by Promoting the Escape From External Cytokine Control von Brandts, Christian H., Reddy, Pavankumar, Sargin, Bülent, Choudhary, Chunaram, Muller-Tidow, Carsten, Berdel, Wolfgang E., Serve, Hubert

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Activation of Wnt signaling in cKit-ITD mediated transformation and imatinib sensitivity in acute myeloid leukemia von Tickenbrock, Lara, Hehn, Sina, Sargin, Bülent, Evers, Georg, NG, Pavankumar Reddy, Choudhary, Chunaram, Berdel, Wolfgang E., Müller-Tidow, Carsten, Serve, Hubert

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Mesenchymal Stems Cells and Regulatory T Cells Inhibit Alloantigen Mediated Graft-Versus-Host Reaction but Also Impair Graft-Versus-Tumor Reactions Targeting Tumor Associated Antig... von Stelljes, Matthias, Harmata, Sarah, Schlösser, Verena, Opitz, Corinna, Albring, Jörn, Rosenow, Felix, Sargin, Bülent, Berdel, Wolfgang E., Kienast, Joachim

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Comprehensive analysis of the mutational status of early colon cancer: Real world data from the AIO ColoPredict registry study von Gisder, Doreen Maria, Wisser, Sarah, Lugnier, Celine, Christmann, Jens, Anna-Lena, Kraeft, Feder, Inke Sabine, Tischoff, Iris, Teschendorf, Christian, Vera, Heuer, Sargin, Bülent, Hollerbach, Stepahn, Lamberti, Christof, Tannapfel, Andrea, Reinacher-Schick, Anke C.

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Cbl Mutants Interact with c-Kit and Lead to Factor Independent Growth and Transformation of a Myeloid Cell Line 32D von Sargin, Bülent, Bandi, Srinivasa Rao, August, Benjamin, Rensinghoff, Marion, Choudhary, Chunaram, Gonchi, Pavan Nagaruri, Berdel, Wolfgang E., Müller-Tidow, Carsten, Serve, Hubert

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Activation Mechanisms of STAT5 by Oncogenic Flt3-ITD von Choudhary, Chunaram, Brandts, Christian, Schwable, Joachim, Tickenbrock, Lara, Sargin, Bulent, Ueker, Andrea, Bohmer, Frank D., Berdel, Wolfgang E., Müller-Tidow, Carsten, Serve, Hubert

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