Non-genetic mechanisms of therapeutic resistance in cancer von Marine, Jean-Christophe, Dawson, Sarah-Jane, Dawson, Mark A.

Volltext

Ibrutinib plus Venetoclax for the Treatment of Mantle-Cell Lymphoma von Tam, Constantine S, Anderson, Mary Ann, Pott, Christiane, Agarwal, Rishu, Handunnetti, Sasanka, Hicks, Rodney J, Burbury, Kate, Turner, Gillian, Di Iulio, Juliana, Bressel, Mathias, Westerman, David, Lade, Stephen, Dreyling, Martin, Dawson, Sarah-Jane, Dawson, Mark A, Seymour, John F, Roberts, Andrew W

Volltext

An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer von Burr, Marian L., Sparbier, Christina E., Chan, Kah Lok, Chan, Yih-Chih, Kersbergen, Ariena, Lam, Enid Y.N., Azidis-Yates, Elizabeth, Vassiliadis, Dane, Bell, Charles C., Gilan, Omer, Jackson, Susan, Tan, Lavinia, Wong, Stephen Q., Hollizeck, Sebastian, Michalak, Ewa M., Siddle, Hannah V., McCabe, Michael T., Prinjha, Rab K., Guerra, Glen R., Solomon, Benjamin J., Sandhu, Shahneen, Dawson, Sarah-Jane, Beavis, Paul A., Tothill, Richard W., Cullinane, Carleen, Lehner, Paul J., Sutherland, Kate D., Dawson, Mark A.

Volltext

The value of cell‐free DNA for molecular pathology von Stewart, Caitlin M, Kothari, Prachi D, Mouliere, Florent, Mair, Richard, Somnay, Saira, Benayed, Ryma, Zehir, Ahmet, Weigelt, Britta, Dawson, Sarah‐Jane, Arcila, Maria E, Berger, Michael F, Tsui, Dana WY

Volltext

A new genome‐driven integrated classification of breast cancer and its implications von Dawson, Sarah‐Jane, Rueda, Oscar M, Aparicio, Samuel, Caldas, Carlos

Volltext

Multi-omic machine learning predictor of breast cancer therapy response von Sammut, Stephen-John, Crispin-Ortuzar, Mireia, Chin, Suet-Feung, Provenzano, Elena, Bardwell, Helen A., Ma, Wenxin, Cope, Wei, Dariush, Ali, Dawson, Sarah-Jane, Abraham, Jean E., Dunn, Janet, Hiller, Louise, Thomas, Jeremy, Cameron, David A., Bartlett, John M. S., Hayward, Larry, Pharoah, Paul D., Markowetz, Florian, Rueda, Oscar M., Earl, Helena M., Caldas, Carlos

Volltext

Non-genetic determinants of malignant clonal fitness at single-cell resolution von Fennell, Katie A., Vassiliadis, Dane, Lam, Enid Y. N., Martelotto, Luciano G., Balic, Jesse J., Hollizeck, Sebastian, Weber, Tom S., Semple, Timothy, Wang, Qing, Miles, Denise C., MacPherson, Laura, Chan, Yih-Chih, Guirguis, Andrew A., Kats, Lev M., Wong, Emily S., Dawson, Sarah-Jane, Naik, Shalin H., Dawson, Mark A.

Volltext

Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA von Murtaza, Muhammed, Dawson, Sarah-Jane, Tsui, Dana W. Y., Gale, Davina, Forshew, Tim, Piskorz, Anna M., Parkinson, Christine, Chin, Suet-Feung, Kingsbury, Zoya, Wong, Alvin S. C., Marass, Francesco, Humphray, Sean, Hadfield, James, Bentley, David, Chin, Tan Min, Brenton, James D., Caldas, Carlos, Rosenfeld, Nitzan

Volltext

Detection of cell-free microbial DNA using a contaminant-controlled analysis framework von Zozaya-Valdés, Enrique, Wong, Stephen Q, Raleigh, Jeanette, Hatzimihalis, Athena, Ftouni, Sarah, Papenfuss, Anthony T, Sandhu, Shahneen, Dawson, Mark A, Dawson, Sarah-Jane

Volltext

Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer von Dawson, Sarah-Jane, Tsui, Dana W.Y, Murtaza, Muhammed, Biggs, Heather, Rueda, Oscar M, Chin, Suet-Feung, Dunning, Mark J, Gale, Davina, Forshew, Tim, Mahler-Araujo, Betania, Rajan, Sabrina, Humphray, Sean, Becq, Jennifer, Halsall, David, Wallis, Matthew, Bentley, David, Caldas, Carlos, Rosenfeld, Nitzan

Volltext

CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity von Burr, Marian L., Sparbier, Christina E., Chan, Yih-Chih, Williamson, James C., Woods, Katherine, Beavis, Paul A., Lam, Enid Y. N., Henderson, Melissa A., Bell, Charles C., Stolzenburg, Sabine, Gilan, Omer, Bloor, Stuart, Noori, Tahereh, Morgens, David W., Bassik, Michael C., Neeson, Paul J., Behren, Andreas, Darcy, Phillip K., Dawson, Sarah-Jane, Voskoboinik, Ilia, Trapani, Joseph A., Cebon, Jonathan, Lehner, Paul J., Dawson, Mark A.

Volltext

BET inhibitor resistance emerges from leukaemia stem cells von Fong, Chun Yew, Gilan, Omer, Lam, Enid Y. N., Rubin, Alan F., Ftouni, Sarah, Tyler, Dean, Stanley, Kym, Sinha, Devbarna, Yeh, Paul, Morison, Jessica, Giotopoulos, George, Lugo, Dave, Jeffrey, Philip, Lee, Stanley Chun-Wei, Carpenter, Christopher, Gregory, Richard, Ramsay, Robert G., Lane, Steven W., Abdel-Wahab, Omar, Kouzarides, Tony, Johnstone, Ricky W., Dawson, Sarah-Jane, Huntly, Brian J. P., Prinjha, Rab K., Papenfuss, Anthony T., Dawson, Mark A.

Volltext

RET Solvent Front Mutations Mediate Acquired Resistance to Selective RET Inhibition in RET-Driven Malignancies von Solomon, Benjamin J., Tan, Lavinia, Lin, Jessica J., Wong, Stephen Q., Hollizeck, Sebastian, Ebata, Kevin, Tuch, Brian B., Yoda, Satoshi, Gainor, Justin F., Sequist, Lecia V., Oxnard, Geoffrey R., Gautschi, Oliver, Drilon, Alexander, Subbiah, Vivek, Khoo, Christine, Zhu, Edward Y., Nguyen, Michele, Henry, Dahlia, Condroski, Kevin R., Kolakowski, Gabrielle R., Gomez, Eliana, Ballard, Joshua, Metcalf, Andrew T., Blake, James F., Dawson, Sarah-Jane, Blosser, Wayne, Stancato, Louis F., Brandhuber, Barbara J., Andrews, Steve, Robinson, Bruce G., Rothenberg, S. Michael

Volltext

Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data von Bidard, François-Clément, MD, Peeters, Dieter J, MD, Fehm, Tanja, Prof, Nolé, Franco, MD, Gisbert-Criado, Rafael, MD, Mavroudis, Dimitrios, Prof, Grisanti, Salvatore, MD, Generali, Daniele, MD, Garcia-Saenz, Jose A, MD, Stebbing, Justin, Prof, Caldas, Carlos, Prof, Gazzaniga, Paola, MD, Manso, Luis, MD, Zamarchi, Rita, MD, de Lascoiti, Angela Fernandez, MD, De Mattos-Arruda, Leticia, MD, Ignatiadis, Michail, MD, Lebofsky, Ronald, PhD, van Laere, Steven J, Prof, Meier-Stiegen, Franziska, PhD, Sandri, Maria-Teresa, MD, Vidal-Martinez, Jose, MD, Politaki, Eleni, MSc, Consoli, Francesca, MD, Bottini, Alberto, MD, Diaz-Rubio, Eduardo, Prof, Krell, Jonathan, MD, Dawson, Sarah-Jane, MD, Raimondi, Cristina, MD, Rutten, Annemie, MD, Janni, Wolfgang, Prof, Munzone, Elisabetta, MD, Carañana, Vicente, MD, Agelaki, Sofia, MD, Almici, Camillo, MD, Dirix, Luc, MD, Solomayer, Erich-Franz, Prof, Zorzino, Laura, MSc, Johannes, Helene, MSc, Reis-Filho, Jorge S, Prof, Pantel, Klaus, Prof, Pierga, Jean-Yves, Prof, Michiels, Stefan, PhD

Volltext

Click chemistry enables preclinical evaluation of targeted epigenetic therapies von Tyler, Dean S., Vappiani, Johanna, Cañeque, Tatiana, Lam, Enid Y. N., Ward, Aoife, Gilan, Omer, Chan, Yih-Chih, Hienzsch, Antje, Rutkowska, Anna, Werner, Thilo, Wagner, Anne J., Lugo, Dave, Gregory, Richard, Molina, Cesar Ramirez, Garton, Neil, Wellaway, Christopher R., Jackson, Susan, MacPherson, Laura, Figueiredo, Margarida, Stolzenburg, Sabine, Bell, Charles C., House, Colin, Dawson, Sarah-Jane, Hawkins, Edwin D., Drewes, Gerard, Prinjha, Rab K., Rodriguez, Raphaël, Grandi, Paola, Dawson, Mark A.

Volltext

Analysis of heterogeneity in T2-weighted MR images can differentiate pseudoprogression from progression in glioblastoma von Booth, Thomas C, Larkin, Timothy J, Yuan, Yinyin, Kettunen, Mikko I, Dawson, Sarah N, Scoffings, Daniel, Canuto, Holly C, Vowler, Sarah L, Kirschenlohr, Heide, Hobson, Michael P, Markowetz, Florian, Jefferies, Sarah, Brindle, Kevin M

Volltext

The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes von Pereira, Bernard, Chin, Suet-Feung, Rueda, Oscar M, Vollan, Hans-Kristian Moen, Provenzano, Elena, Bardwell, Helen A, Pugh, Michelle, Jones, Linda, Russell, Roslin, Sammut, Stephen-John, Tsui, Dana W Y, Liu, Bin, Dawson, Sarah-Jane, Abraham, Jean, Northen, Helen, Peden, John F, Mukherjee, Abhik, Turashvili, Gulisa, Green, Andrew R, McKinney, Steve, Oloumi, Arusha, Shah, Sohrab, Rosenfeld, Nitzan, Murphy, Leigh, Bentley, David R, Ellis, Ian O, Purushotham, Arnie, Pinder, Sarah E, Børresen-Dale, Anne-Lise, Earl, Helena M, Pharoah, Paul D, Ross, Mark T, Aparicio, Samuel, Caldas, Carlos

Volltext

Reversion of BRCA1/2 Germline Mutations Detected in Circulating Tumor DNA From Patients With High-Grade Serous Ovarian Cancer von Christie, Elizabeth L, Fereday, Sian, Doig, Ken, Pattnaik, Swetansu, Dawson, Sarah-Jane, Bowtell, David D L

Volltext

HIV is associated with an increased risk of age-related clonal hematopoiesis among older adults von Dharan, Nila J., Yeh, Paul, Bloch, Mark, Yeung, Miriam M., Baker, David, Guinto, Jerick, Roth, Norman, Ftouni, Sarah, Ognenovska, Katherine, Smith, Don, Hoy, Jennifer F., Woolley, Ian, Pell, Catherine, Templeton, David J., Fraser, Neil, Rose, Nectarios, Hutchinson, Jolie, Petoumenos, Kathy, Dawson, Sarah-Jane, Polizzotto, Mark N., Dawson, Mark A.

Volltext

Circulating tumour DNA reflects treatment response and clonal evolution in chronic lymphocytic leukaemia von Yeh, Paul, Hunter, Tane, Sinha, Devbarna, Ftouni, Sarah, Wallach, Elise, Jiang, Damian, Chan, Yih-Chih, Wong, Stephen Q., Silva, Maria Joao, Vedururu, Ravikiran, Doig, Kenneth, Lam, Enid, Arnau, Gisela Mir, Semple, Timothy, Wall, Meaghan, Zivanovic, Andjelija, Agarwal, Rishu, Petrone, Pasquale, Jones, Kate, Westerman, David, Blombery, Piers, Seymour, John F., Papenfuss, Anthony T., Dawson, Mark A., Tam, Constantine S., Dawson, Sarah-Jane

Volltext