Long-Acting Anti-HIV Drugs Targeting HIV-1 Reverse Transcriptase and Integrase von Singh, Kamal, Sarafianos, Stefan G, Sönnerborg, Anders

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Ex-vivo antiretroviral potency of newer integrase strand transfer inhibitors cabotegravir and bictegravir in HIV type 1 non-B subtypes von Neogi, Ujjwal, Singh, Kamalendra, Aralaguppe, Shambhu G, Rogers, Leonard C, Njenda, Duncan T, Sarafianos, Stefan G, Hejdeman, Bo, Sönnerborg, Anders

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Antiretroviral potency of 4'-ethnyl-2'-fluoro-2'-deoxyadenosine, tenofovir alafenamide and second-generation NNRTIs across diverse HIV-1 subtypes von Njenda, Duncan T, Aralaguppe, Shambhu G, Singh, Kamalendra, Rao, Rohit, Sönnerborg, Anders, Sarafianos, Stefan G, Neogi, Ujjwal

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Structural Implications of Genotypic Variations in HIV-1 Integrase From Diverse Subtypes von Rogers, Leonard, Obasa, Adetayo E, Jacobs, Graeme B, Sarafianos, Stefan G, Sönnerborg, Anders, Neogi, Ujjwal, Singh, Kamalendra

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Strain-specific effect on biphasic DNA binding by HIV-1 integrase von Hill, Kyle J, Rogers, Leonard C, Njenda, Duncan T, Burke, Donald H, Sarafianos, Stefan G, Sönnerborg, Anders, Neogi, Ujjwal, Singh, Kamalendra

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Feasibility of Known RNA Polymerase Inhibitors as Anti-SARS-CoV-2 Drugs von Neogi, Ujjwal, Hill, Kyle J, Ambikan, Anoop T, Heng, Xiao, Quinn, Thomas P, Byrareddy, Siddappa N, Sönnerborg, Anders, Sarafianos, Stefan G, Singh, Kamal

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Increased replication capacity following evolution of PYxE insertion in Gag‐p6 is associated with enhanced virulence in HIV‐1 subtype C from East Africa von Aralaguppe, Shambhu G., Winner, Dane, Singh, Kamalendra, Sarafianos, Stefan G., Quiñones‐Mateu, Miguel E., Sönnerborg, Anders, Neogi, Ujjwal

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Taking aim at a moving target: designing drugs to inhibit drug-resistant HIV-1 reverse transcriptases von Sarafianos, Stefan G, Das, Kalyan, Hughes, Stephen H, Arnold, Eddy

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Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA von Sarafianos, Stefan G., Das, Kalyan, Tantillo, Chris, Clark Jr, Arthur D., Ding, Jianping, Whitcomb, Jeannette M., Boyer, Paul L., Hughes, Stephen H., Arnold, Edward

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Molecular model of SARS coronavirus polymerase: implications for biochemical functions and drug design von Xu, Xiang, Liu, Yunqing, Weiss, Susan, Arnold, Eddy, Sarafianos, Stefan G., Ding, Jianping

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Inhibition of Bacterial RNA Polymerase by Streptolydigin: Stabilization of a Straight-Bridge-Helix Active-Center Conformation von Tuske, Steven, Sarafianos, Stefan G., Wang, Xinyue, Hudson, Brian, Sineva, Elena, Mukhopadhyay, Jayanta, Birktoft, Jens J., Leroy, Olivier, Ismail, Sajida, Clark, Arthur D., Dharia, Chhaya, Napoli, Andrew, Laptenko, Oleg, Lee, Jookyung, Borukhov, Sergei, Ebright, Richard H., Arnold, Eddy

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Selective Excision of AZTMP by Drug-Resistant Human Immunodeficiency Virus Reverse Transcriptase von Boyer, P L, Sarafianos, S G, Arnold, E, Hughes, S H

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Factors influencing the efficacy of rilpivirine in HIV-1 subtype C in low- and middle-income countries von Neogi, Ujjwal, Häggblom, Amanda, Singh, Kamalendra, Rogers, Leonard C, Rao, Shwetha D, Amogne, Wondwossen, Schülter, Eugen, Zazzi, Maurizio, Arnold, Eddy, Sarafianos, Stefan G, Sönnerborg, Anders

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Molecular Modeling and Biochemical Characterization Reveal the Mechanism of Hepatitis B Virus Polymerase Resistance to Lamivudine (3TC) and Emtricitabine (FTC) von Das, K, Xiong, X, Yang, H, Westland, C E, Gibbs, C S, Sarafianos, S G, Arnold, E

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Expression, purification, and characterization of SARS coronavirus RNA polymerase von Cheng, Ao, Zhang, Wei, Xie, Youhua, Jiang, Weihong, Arnold, Eddy, Sarafianos, Stefan G., Ding, Jianping

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Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA von Sarafianos, Stefan G., Clark Jr, Arthur D., Das, Kalyan, Tuske, Steve, Birktoft, Jens J., Ilankumaran, Palanichamy, Ramesha, Andagar R., Sayer, Jane M., Jerina, Donald M., Boyer, Paul L., Hughes, Stephen H., Arnold, Eddy

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Lamivudine (3TC) Resistance in HIV-1 Reverse Transcriptase Involves Steric Hindrance with β -Branched Amino Acids von Sarafianos, Stefan G., Das, Kalyan, Clark, Arthur D., Ding, Jianping, Boyer, Paul L., Hughes, Stephen H., Arnold, Edward

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Structures of HIV-1 RT–DNA complexes before and after incorporation of the anti-AIDS drug tenofovir von Tuske, Steve, Sarafianos, Stefan G, Clark, Arthur D, Ding, Jianping, Naeger, Lisa K, White, Kirsten L, Miller, Michael D, Gibbs, Craig S, Boyer, Paul L, Clark, Patrick, Wang, Gang, Gaffney, Barbara L, Jones, Roger A, Jerina, Donald M, Hughes, Stephen H, Arnold, Eddy

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Nucleoside Analog Resistance Caused by Insertions in the Fingers of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Involves ATP-Mediated Excision von Boyer, Paul L, Sarafianos, Stefan G, Arnold, Edward, Hughes, Stephen H

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Designing anti-AIDS drugs targeting the major mechanism of HIV-1 RT resistance to nucleoside analog drugs von Sarafianos, Stefan G, Hughes, Stephen H, Arnold, Eddy

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