The multi-target aspect of an MmpL3 inhibitor: The BM212 series of compounds bind EthR2, a transcriptional regulator of ethionamide activation von Moorey, Alice R., Cabanillas, Alejandro, Batt, Sarah M., Ghidelli-Disse, Sonja, Urones, Beatriz, Sanz, Olalla, Lelievre, Joel, Bantscheff, Marcus, Cox, Liam R., Besra, Gurdyal S.

Volltext

Cyclic AMP-Mediated Inhibition of Cholesterol Catabolism in Mycobacterium tuberculosis by the Novel Drug Candidate GSK2556286 von Brown, Kirstin L, Wilburn, Kaley M, Montague, Christine R, Grigg, Jason C, Sanz, Olalla, Pérez-Herrán, Esther, Barros, David, Ballell, Lluís, VanderVen, Brian C, Eltis, Lindsay D

Volltext

Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity von Vanaerschot, Manu, Murithi, James M., Pasaje, Charisse Flerida A., Ghidelli-Disse, Sonja, Dwomoh, Louis, Bird, Megan, Spottiswoode, Natasha, Mittal, Nimisha, Arendse, Lauren B., Owen, Edward S., Wicht, Kathryn J., Siciliano, Giulia, Bösche, Markus, Yeo, Tomas, Kumar, T.R. Santha, Mok, Sachel, Carpenter, Emma F., Giddins, Marla J., Sanz, Olalla, Ottilie, Sabine, Alano, Pietro, Chibale, Kelly, Llinás, Manuel, Uhlemann, Anne-Catrin, Delves, Michael, Tobin, Andrew B., Doerig, Christian, Winzeler, Elizabeth A., Lee, Marcus C.S., Niles, Jacquin C., Fidock, David A.

Volltext

GSK2556286 Is a Novel Antitubercular Drug Candidate Effective In Vivo with the Potential To Shorten Tuberculosis Treatment von Nuermberger, Eric L, Martínez-Martínez, Maria Santos, Sanz, Olalla, Urones, Beatriz, Esquivias, Jorge, Soni, Heena, Tasneen, Rokeya, Tyagi, Sandeep, Li, Si-Yang, Converse, Paul J, Boshoff, Helena I, Robertson, Gregory T, Besra, Gurdyal S, Abrahams, Katherine A, Upton, Anna M, Mdluli, Khisimuzi, Boyle, Gary W, Turner, Sam, Fotouhi, Nader, Cammack, Nicholas C, Siles, Juan Miguel, Alonso, Marta, Escribano, Jaime, Lelievre, Joel, Rullas-Trincado, Joaquin, Pérez-Herrán, Esther, Bates, Robert H, Maher-Edwards, Gareth, Barros, David, Ballell, Lluís, Jiménez, Elena

Volltext

Exploration of the P1 residue in 3CL protease inhibitors leading to the discovery of a 2-tetrahydrofuran P1 replacement von Barton, Linda S., Callahan, James F., Cantizani, Juan, Concha, Nestor O., Cotillo Torrejon, Ignacio, Goodwin, Nicole C., Joshi-Pangu, Amruta, Kiesow, Terry J., McAtee, Jeff J., Mellinger, Mark, Nixon, Christopher J., Padrón-Barthe, Laura, Patterson, Jaclyn R., Pearson, Neil D., Pouliot, Jeffrey J., Rendina, Alan R., Buitrago Santanilla, Alexander, Schneck, Jessica L., Sanz, Olalla, Thalji, Reema K., Ward, Paris, Williams, Shawn P., King, Bryan W.

Volltext

Novel Antitubercular 6‑Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure–Activity Relationship and Target I... von Wilson, Colin R, Gessner, Richard K, Moosa, Atica, Seldon, Ronnett, Warner, Digby F, Mizrahi, Valerie, Soares de Melo, Candice, Simelane, Sandile B, Nchinda, Aloysius, Abay, Efrem, Taylor, Dale, Njoroge, Mathew, Brunschwig, Christel, Lawrence, Nina, Boshoff, Helena I. M, Barry, Clifton E, Sirgel, Frederick A, van Helden, Paul, Harris, C. John, Gordon, Richard, Ghidelli-Disse, Sonja, Pflaumer, Hannah, Boesche, Markus, Drewes, Gerard, Sanz, Olalla, Santos, Gracia, Rebollo-Lopez, Maria José, Urones, Beatriz, Selenski, Carolyn, Lafuente-Monasterio, Maria Jose, Axtman, Matthew, Lelièvre, Joël, Ballell, Lluis, Mueller, Rudolf, Street, Leslie J, Ghorpade, Sandeep R, Chibale, Kelly

Volltext

Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity von Vanaerschot, Manu, Murithi, James M, Pasaje, Charisse Flerida A, Ghidelli-Disse, Sonja, Dwomoh, Louis, Bird, Megan, Spottiswoode, Natasha, Mittal, Nimisha, Arendse, Lauren B, Owen, Edward S, Wicht, Kathryn J, Siciliano, Giulia, Bösche, Markus, Yeo, Tomas, Kumar, TR Santha, Mok, Sachel, Carpenter, Emma F, Giddins, Marla J, Sanz, Olalla, Ottilie, Sabine, Alano, Pietro, Chibale, Kelly, Llinás, Manuel, Uhlemann, Anne-Catrin, Delves, Michael, Tobin, Andrew B, Doerig, Christian, Winzeler, Elizabeth A, Lee, Marcus CS, Niles, Jacquin C, Fidock, David A

Volltext

Ca2+ signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKG von Balestra, Aurelia C., Koussis, Konstantinos, Klages, Natacha, Howell, Steven A., Flynn, Helen R., Bantscheff, Marcus, Pasquarello, Carla, Perrin, Abigail J., Brusini, Lorenzo, Arboit, Patrizia, Sanz, Olalla, Castano, Laura Peces-Barba, Withers-Martinez, Chrislaine, Hainard, Alexandre, Ghidelli-Disse, Sonja, Snijders, Ambrosius P., Baker, David A., Blackman, Michael J., Brochet, Mathieu

Volltext

1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in Mycobacterium tuberculosis von Singh, Vinayak, Grzegorzewicz, Anna E., Fienberg, Stephen, Müller, Rudolf, Khonde, Lutete Peguy, Sanz, Olalla, Alfonso, Salvatore, Urones, Beatriz, Drewes, Gerard, Bantscheff, Marcus, Ghidelli-Disse, Sonja, Ioerger, Thomas R., Angala, Bhanupriya, Liu, Jiuyu, Lee, Richard E., Sacchettini, James C., Krieger, Inna V., Jackson, Mary, Chibale, Kelly, Ghorpade, Sandeep R.

Volltext

Ca2+ signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKG von Balestra, Aurélia C, Koussis, Konstantinos, Klages, Natacha, Howell, Steven A, Flynn, Helen R, Bantscheff, Marcus, Pasquarello, Carla, Perrin, Abigail J, Brusini, Lorenzo, Arboit, Patrizia, Sanz, Olalla, Castaño, Laura Peces-Barba, Withers-Martinez, Chrislaine, Hainard, Alexandre, Ghidelli-Disse, Sonja, Snijders, Ambrosius P, Baker, David A, Blackman, Michael J, Brochet, Mathieu

Volltext

Ca 2+ signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKG von Balestra, Aurélia C, Koussis, Konstantinos, Klages, Natacha, Howell, Steven A, Flynn, Helen R, Bantscheff, Marcus, Pasquarello, Carla, Perrin, Abigail J, Brusini, Lorenzo, Arboit, Patrizia, Sanz, Olalla, Castaño, Laura Peces-Barba, Withers-Martinez, Chrislaine, Hainard, Alexandre, Ghidelli-Disse, Sonja, Snijders, Ambrosius P, Baker, David A, Blackman, Michael J, Brochet, Mathieu

Volltext

Symmetry resolved entanglement of excited states in quantum field theory. Part I. Free theories, twist fields and qubits von Capizzi, Luca, Castro-Alvaredo, Olalla A., De Fazio, Cecilia, Mazzoni, Michele, Santamaría-Sanz, Lucía

Volltext

Symmetry resolved entanglement of excited states in quantum field theory. Part II. Numerics, interacting theories and higher dimensions von Capizzi, Luca, De Fazio, Cecilia, Mazzoni, Michele, Santamaría-Sanz, Lucía, Castro-Alvaredo, Olalla A.

Volltext

Socioeconomic Inequalities in COVID-19 in a European Urban Area: Two Waves, Two Patterns von Mari-Dell'Olmo, Marc, Gotsens, Merce, Pasarin, M. Isabel, Rodriguez-Sanz, Maica, Artazcoz, Lucia, Garcia de Olalla, Patricia, Rius, Cristina, Borrell, Carme

Volltext

Gold-Catalyzed Synthesis of 1‑(Indol-3-yl)carbazoles: Selective 1,2-Alkyl vs 1,2-Vinyl Migration von Suárez, Anisley, Suárez-Pantiga, Samuel, Nieto-Faza, Olalla, Sanz, Roberto

Volltext

Deciphering Nitroaromatics Reduction: Theoretical Insights into Dioxomolybdenum Catalysis with Biomass‐Derived Pinacol von Kiriakidi, Sofia, Silva López, Carlos, Sanz, Roberto, Faza, Olalla Nieto

Volltext

The Experience of Implementing Urban HEART Barcelona: a Tool for Action von Novoa, Ana M., Pérez, Glòria, Espelt, Albert, Echave, Cynthia, de Olalla, Patricia G., Calvo, M. Jesús, Pasarín, Maribel, Diez, Èlia, Borrell, Carme, Calvo, M. Jesús, Cormenzana, Berta, Cortés, Imma, Diez, Èlia, Echave, Cynthia, Espelt, Albert, de Olalla, Patrícia G., Gòmez, Josep, Novoa, Ana M., Pallarès, Montserrat, Pérez, Glòria, Rodríguez-Sanz, Maica

Volltext

Brønsted Acid-Catalyzed Cascade Reactions Involving 1,2-Indole Migration von Álvarez, Estela, Nieto Faza, Olalla, Silva López, Carlos, Fernández-Rodríguez, Manuel A., Sanz, Roberto

Volltext

Social inequalities in the association between temperature and mortality in a South European context von Marí-Dell’Olmo, Marc, Tobías, Aurelio, Gómez-Gutiérrez, Anna, Rodríguez-Sanz, Maica, García de Olalla, Patricia, Camprubí, Esteve, Gasparrini, Antonio, Borrell, Carme

Volltext

Influence of Natural Cavities on the Design of Shallow Foundations von Benito Olmeda, Jesus Luis, Moreno Robles, Javier, Sanz Perez, Eugenio, Olalla Maranon, Claudio

Volltext