TGF-beta/atRA-induced Tregs express a selected set of microRNAs involved in the repression of transcripts related to Th17 differentiation von Schiavinato, Josiane Lilian dos Santos, Haddad, Rodrigo, Saldanha-Araujo, Felipe, Baiochi, João, Araujo, Amélia Goes, Santos Scheucher, Priscila, Covas, Dimas Tadeu, Zago, Marco Antonio, Panepucci, Rodrigo Alexandre

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IGF1R/IRS1 targeting has cytotoxic activity and inhibits PI3K/AKT/mTOR and MAPK signaling in acute lymphoblastic leukemia cells von Rodrigues Alves, Ana Paula Nunes, Fernandes, Jaqueline Cristina, Fenerich, Bruna Alves, Coelho-Silva, Juan Luiz, Scheucher, Priscila Santos, Simões, Belinda Pinto, Rego, Eduardo Magalhães, Ridley, Anne J., Machado-Neto, João Agostinho, Traina, Fabiola

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STMN1 is highly expressed and contributes to clonogenicity in acute promyelocytic leukemia cells von Vicari, Hugo Passos, Coelho-Silva, Juan Luiz, Pereira-Martins, Diego A., Lucena-Araujo, Antônio Roberto, Lima, Keli, Lipreri da Silva, Jean Carlos, Scheucher, Priscila Santos, Koury, Luisa C., de Melo, Raul A., Bittencourt, Rosane, Pagnano, Katia, Nunes, Elenaide, Fagundes, Evandro M., Kerbauy, Fabio, de Figueiredo-Pontes, Lorena Lobo, Costa-Lotufo, Leticia Veras, Rego, Eduardo Magalhães, Traina, Fabiola, Machado-Neto, João Agostinho

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Phenformin increases early hematopoietic progenitors in the Jak2V617F murine model von Alves-Silva, Antônio Bruno, Fenerich, Bruna Alves, Fonseca, Natasha Peixoto, Fernandes, Jaqueline Cristina, Coelho-Silva, Juan Luiz, Pereira-Martins, Diego Antonio, Bianco, Thiago Mantello, Scheucher, Priscila Santos, Rego, Eduardo Magalhães, Chahud, Fernando, Machado-Neto, João Agostinho, Figueiredo-Pontes, Lorena Lôbo, Traina, Fabiola

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The application of an integrated clinical, cytogenetic, and molecular risk stratification for acute myeloid leukemia patients using a central laboratory in a Brazilian multicentric... von Borges da Silva, Fernanda, de Figueiredo-Pontes, Lorena Lobo, Madeira, Maria Isabel Ayrosa, Corrêa de Araujo Koury, Luisa, Gouvêa de Lima, Ana Silvia, Santos Scheucher, Priscila, Coelho-Silva, Juan Luiz, Pagnano, Katia Borgia Barbosa, Pallota, Ronald, de Lourdes Chauffaille, Maria, Oltramari, Marcos Roberto Pedron, Bittencourt, Rosane Isabel, Higashi, Marcia, Bendlin, Rodrigo Miguel, Rodrigues Pereira Velloso, Elvira Deolinda, Lowenberg, Bob, Ganser, Arnold, Berliner, Nancy, Valk, Peter, Magalhães Rego, Eduardo, Traina, Fabiola

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Autophagy inhibition potentiates ruxolitinib-induced apoptosis in JAK2V617F cells von Machado-Neto, João Agostinho, Coelho-Silva, Juan Luiz, Santos, Fábio Pires de Souza, Scheucher, Priscila Santos, Campregher, Paulo Vidal, Hamerschlak, Nelson, Rego, Eduardo Magalhães, Traina, Fabiola

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NT157, an IGF1R-IRS1/2 inhibitor, exhibits antineoplastic effects in pre-clinical models of chronic myeloid leukemia von Scopim-Ribeiro, Renata, Machado-Neto, João Agostinho, Eide, Christopher A., Coelho-Silva, Juan Luiz, Fenerich, Bruna Alves, Fernandes, Jaqueline Cristina, Scheucher, Priscila Santos, Savage Stevens, Samantha L., de Melo Campos, Paula, Olalla Saad, Sara T., de Carvalho Palma, Leonardo, de Figueiredo-Pontes, Lorena Lobo, Simões, Belinda Pinto, Rego, Eduardo Magalhães, Tognon, Cristina E., Druker, Brian J., Traina, Fabiola

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NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia von Thomé, Carolina Hassibe, Ferreira, Germano Aguiar, Pereira-Martins, Diego Antonio, dos Santos, Guilherme Augusto, Ortiz, César Alexander, de Souza, Lucas Eduardo Botelho, Sobral, Lays Martins, Silva, Cleide Lúcia Araújo, Scheucher, Priscila Santos, Gil, Cristiane Damas, Leopoldino, Andréia Machado, Silveira, Douglas R. A., Coelho-Silva, Juan L., Traina, Fabíola, Koury, Luisa C., Melo, Raul A. M., Bittencourt, Rosane, Pagnano, Katia, Pasquini, Ricardo, Nunes, Elenaide C., Fagundes, Evandro M., Gloria, Ana Beatriz F., Kerbauy, Fábio Rodrigues, Chauffaille, Maria de Lourdes, Keating, Armand, Tallman, Martin S., Ribeiro, Raul C., Dillon, Richard, Ganser, Arnold, Löwenberg, Bob, Valk, Peter, Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Faça, Vitor Marcel, Rego, Eduardo M.

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Altered distribution and function of NK-cell subsets lead to impaired tumor surveillance in JAK2V617F myeloproliferative neoplasms von Fernandes de Oliveira Costa, Amanda, Olops Marani, Leticia, Mantello Bianco, Thiago, Queiroz Arantes, Adriana, Aparecida Lopes, Izabela, Antonio Pereira-Martins, Diego, Carvalho Palma, Leonardo, Santos Scheucher, Priscila, Lilian Dos Santos Schiavinato, Josiane, Sarri Binelli, Larissa, Araújo Silva, Cleide, Kobayashi, Susumu S, Agostinho Machado-Neto, João, Magalhães Rego, Eduardo, Samuel Welner, Robert, Lobo de Figueiredo-Pontes, Lorena

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Interleukin-8 is not a predictive biomarker for the development of the acute promyelocytic leukemia differentiation syndrome von de Almeida, Luciana Yamamoto, Pereira-Martins, Diego Antonio, Gouvea Lima, Ana Silvia, Baggio, Marcia Sueli, de Araujo Koury, Luisa Correa, Lange, Ana Paula, Bassi, Sarah Cristina, Scheucher, Priscila Santos, Rego, Eduardo Magalhaes

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Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms von Machado-Neto, João Agostinho, Fenerich, Bruna Alves, Scopim-Ribeiro, Renata, Eide, Christopher A., Coelho-Silva, Juan Luiz, Dechandt, Carlos Roberto Porto, Fernandes, Jaqueline Cristina, Rodrigues Alves, Ana Paula Nunes, Scheucher, Priscila Santos, Simões, Belinda Pinto, Alberici, Luciane Carla, de Figueiredo Pontes, Lorena Lôbo, Tognon, Cristina E., Druker, Brian J., Rego, Eduardo Magalhães, Traina, Fabiola

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NT157 has antineoplastic effects and inhibits IRS1/2 and STAT3/5 in JAK2V617F-positive myeloproliferative neoplasm cells von Fenerich, Bruna Alves, Fernandes, Jaqueline Cristina, Rodrigues Alves, Ana Paula Nunes, Coelho-Silva, Juan Luiz, Scopim-Ribeiro, Renata, Scheucher, Priscila Santos, Eide, Christopher A., Tognon, Cristina E., Druker, Brian J., Rego, Eduardo Magalhães, Machado-Neto, João Agostinho, Traina, Fabiola

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Evaluating the use of fluorescence-based flow cytometry assay for dengue diagnosis using peripheral blood mononuclear cells von Barreira, Luzia Aparecida Costa, Scheucher, Priscila Santos, Romeiro, Marilia Farignoli, Serra, Leonardo La, Badra, Soraya Jabur, Souza, William Marciel de, Figueiredo, Luiz Tadeu Moraes

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Paclitaxel induces Stathmin 1 phosphorylation, microtubule stability and apoptosis in acute lymphoblastic leukemia cells von Machado-Neto, João Agostinho, Rodrigues Alves, Ana Paula Nunes, Fernandes, Jaqueline Cristina, Coelho-Silva, Juan Luiz, Scopim-Ribeiro, Renata, Fenerich, Bruna Alves, da Silva, Fernanda Borges, Scheucher, Priscila Santos, Simões, Belinda Pinto, Rego, Eduardo Magalhães, Traina, Fabiola

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Autophagy Induction Constitutes a Targetable Vulnerability in FLT3-Mutant Acute Myeloid Leukemia Cells Treated with FLT3-Inhibitors von de Melo, Manuela Albuquerque, Macedo, Brunno Gilberto Santos, Fonseca, Natasha Peixoto, Scheucher, Priscila Santos, Pereira-Martins, Diego A, Machado-Neto, João Agostinho, Traina, Fabiola

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Feasibility of minimal residual disease studies by multiparametric flow cytometry for acute myeloid leukemia in a developing country von Lobo de Figueiredo-Pontes, Lorena, Madeira, Maria Isabel Ayrosa, Corrêa de Araujo, Luisa Koury, Scheucher, Priscila Santos, Traina, Fabíola, Gouvêa de Lima, Ana Silvia, Pagnano, Katia, Pallota, Ronald, Bittencourt, Rosane, de Lourdes Chauffaille, Maria, Oltramari, Marcos Roberto Pedron, Higashi, Marcia, Bendlin, Rodrigo Miguel, Coustan-Smith, Elaine, Campana, Dario, Rego, Eduardo Magalhães

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Jak2V617F Bone Marrow Exposure Leads to Dysfunction of Normal NK Cells von Lopes, Izabela Aparecida, Garcia, Camila Araújo Bernardino, Marini, Leticia Olops, Costa, Amanda Fernandes Oliveira, Binelli, Larissa Sarri, Medeiros, Mariana, Schiavinato, Josiane Lillian, Scheucher, Priscila Santos, Silva, Cleide Lúcia Araújo, Figueiredo-Pontes, Lorena Lobo

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Eltrombopag Specifically Expands Hematopoietic Multipotent Progenitors in Human Aplastic Anemia von Oliveira, Bruno Quintino, Santana, Bárbara, Catto, Luiz Fernando Bazzo, Tellechea, Maria Florencia, Scheucher, Priscila Santos, Scheinberg, Phillip, Calado, Rodrigo T.

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Autophagy inhibition potentiates ruxolitinib-induced apoptosis in JAK2(V617F) cells von Machado-Neto, Joao Agostinho, Coelho-Silva, Juan Luiz, de Souza Santos, Fabio Pires, Scheucher, Priscila Santos, Campregher, Paulo Vidal, Hamerschlak, Nelson, Rego, Eduardo Magalhaes, Traina, Fabiola

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Autophagy Inhibition Potentiates Ruxolitinib-Induced Apoptosis in JAK2V617F Cells von Machado-Neto, João Agostinho, Coelho-Silva, Juan Luiz, Santos, Fábio Pires de Souza, Scheucher, Priscila Santos, Campregher, Paulo Vidal, Hamerschlak, Nelson, Rego, Eduardo Magalhães, Traina, Fabiola

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