Integration of functional assay data results provides strong evidence for classification of hundreds of BRCA1 variants of uncertain significance von Lyra, Paulo C. M., Nepomuceno, Thales C., de Souza, Marcele L. M., Machado, Géssica F., Veloso, Mariana F., Henriques, Taciane B., dos Santos, Diandra Z., Ribeiro, Iuly G., Ribeiro, Roberto S., Rangel, Leticia B. A., Richardson, Marcy, Iversen, Edwin S., Goldgar, David, Couch, Fergus J., Carvalho, Marcelo A., Monteiro, Alvaro N. A.

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Prostate cancer cell proliferation is influenced by LDL-cholesterol availability and cholesteryl ester turnover von Raftopulos, Nikki L, Washaya, Tinashe C, Niederprüm, Andreas, Egert, Antonia, Hakeem-Sanni, Mariam F, Varney, Bianca, Aishah, Atqiya, Georgieva, Mariya L, Olsson, Ellinor, Dos Santos, Diandra Z, Nassar, Zeyad D, Cochran, Blake J, Nagarajan, Shilpa R, Kakani, Meghna S, Hastings, Jordan F, Croucher, David R, Rye, Kerry-Anne, Butler, Lisa M, Grewal, Thomas, Hoy, Andrew J

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Abstract 5883: Phosphodiesterase 7-A is a novel potential therapeutic target against ovarian cancer von Tessarollo, Nayara G., Guimarães, Isabella S., Santos, Diandra Z. dos, Henriques, Taciane B., Souza, Marcele LM, Maciel, Laura, Almeida, João Carlos A., Branco, Alan, Silva, Ian V., Rangel, Leticia BA

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Inhibition of CXCR2 plays a pivotal role in re-sensitizing ovarian cancer to cisplatin treatment von Henriques, Taciane Barbosa, dos Santos, Diandra Zipinotti, dos Santos Guimarães, Isabella, Tessarollo, Nayara Gusmão, Lyra-Junior, Paulo Cilas Morais, Mesquita, Patricia, Pádua, Diana, Amaral, Ana Luisa, Cavadas, Bruno, Pereira, Luisa, Silva, Ian Victor, Almeida, Raquel Maria da Silva Graça, Rangel, Leticia Batista Azevedo

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Sterol-like drugs potentiate statin-triggered prostate cancer cell death by inhibiting SREBP2 nuclear translocation von dos Santos, Diandra Zipinotti, Elbaz, Mohamad, Branchard, Emily, Schormann, Wiebke, Brown, Carla E., Meek, Autumn R., Njar, Vincent C.O., Hamilton, Robert J., Reed, Mark A., Andrews, David W., Penn, Linda Z.

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Abstract B073: Inhibiting prostate cancer by targeting the metabolic mevalonate pathway von Santos, Diandra Zipinotti dos, Elbaz, Mohamad, Branchard, Emily, Schormann, Wiebke, Andrews, David W., Penn, Linda Z.

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