Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome von Goicoechea de Jorge, Elena, Harris, Claire L, Esparza-Gordillo, Jorge, Carreras, Luis, Aller Arranz, Elena, Abarrategui Garrido, Cynthia, López-Trascasa, Margarita, Sánchez-Corral, Pilar, Morgan, B. Paul, Rodríguez de Córdoba, Santiago

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The crystal structure of iC3b-CR3 αI reveals a modular recognition of the main opsonin iC3b by the CR3 integrin receptor von Fernández, Francisco J., Santos-López, Jorge, Martínez-Barricarte, Rubén, Querol-García, Javier, Martín-Merinero, Héctor, Navas-Yuste, Sergio, Savko, Martin, Shepard, William E., Rodríguez de Córdoba, Santiago, Vega, M. Cristina

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Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk von Heurich, Meike, Martínez-Barricarte, Ruben, Francis, Nigel J, Roberts, Dawn L, Rodríguez de Córdoba, Santiago, Morgan, B. Paul, Harris, Claire L

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Structural basis for the stabilization of the complement alternative pathway C3 convertase by properdin von Alcorlo, Martin, Tortajada, Agustín, de Córdoba, Santiago Rodríguez, Llorca, Oscar

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Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation von Martínez-Barricarte, Rubén, Heurich, Meike, Valdes-Cañedo, Francisco, Vazquez-Martul, Eduardo, Torreira, Eva, Montes, Tamara, Tortajada, Agustín, Pinto, Sheila, Lopez-Trascasa, Margarita, Morgan, B Paul, Llorca, Oscar, Harris, Claire L, Rodríguez de Córdoba, Santiago

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Investigación multidisciplinar y traslacional en enfermedades raras von Rodríguez de Córdoba, Santiago, Bernabéu, Carmelo

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Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complement activation gene cluster in 1q32 von Esparza-Gordillo, Jorge, Jorge, Elena Goicoechea de, Buil, Alfonso, Berges, Luis Carreras, López-Trascasa, Margarita, Sánchez-Corral, Pilar, Córdoba, Santiago Rodríguez de

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Abnormal glycogen chain length pattern, not hyperphosphorylation, is critical in Lafora disease von Nitschke, Felix, Sullivan, Mitchell A, Wang, Peixiang, Zhao, Xiaochu, Chown, Erin E, Perri, Ami M, Israelian, Lori, Juana‐López, Lucia, Bovolenta, Paola, Rodríguez de Córdoba, Santiago, Steup, Martin, Minassian, Berge A

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Pleiotropic effects of cell wall amidase LytA on Streptococcus pneumoniae sensitivity to the host immune response von Ramos-Sevillano, Elisa, Urzainqui, Ana, Campuzano, Susana, Moscoso, Miriam, González-Camacho, Fernando, Domenech, Mirian, Rodríguez de Córdoba, Santiago, Sánchez-Madrid, Francisco, Brown, Jeremy S, García, Ernesto, Yuste, Jose

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Complement Factor D (adipsin) Levels Are Elevated in Acquired Partial Lipodystrophy (Barraquer–Simons syndrome) von Corvillo, Fernando, González-Sánchez, Laura, López-Lera, Alberto, Arjona, Emilia, Ceccarini, Giovanni, Santini, Ferruccio, Araújo-Vilar, David, Brown, Rebecca J, Villarroya, Joan, Villarroya, Francesc, Rodríguez de Córdoba, Santiago, Caballero, Teresa, Nozal, Pilar, López-Trascasa, Margarita

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Atypical hemolytic uremic syndrome-associated variants and autoantibodies impair binding of factor h and factor h-related protein 1 to pentraxin 3 von Kopp, Anne, Strobel, Stefanie, Tortajada, Agustín, Rodríguez de Córdoba, Santiago, Sánchez-Corral, Pilar, Prohászka, Zoltán, López-Trascasa, Margarita, Józsi, Mihály

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Characteristics, management and outcomes of atypical haemolytic uraemic syndrome in kidney transplant patients: a retrospective national study von Portoles, José, Huerta, Ana, Arjona, Emilia, Gavela, Eva, Agüera, Marisa, Jiménez, Carlos, Cavero, Teresa, Marrero, Domingo, Rodríguez de Córdoba, Santiago, Diekmann, Fritz

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Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B von Montes, Tamara, Tortajada, Agustín, Morgan, B. Paul, Rodríguez de Córdoba, Santiago, Harris, Claire L

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High Complement Factor H-Related (FHR)-3 Levels Are Associated With the Atypical Hemolytic-Uremic Syndrome-Risk Allele CFHR3B von Pouw, Richard B, Gómez Delgado, Irene, López Lera, Alberto, Rodríguez de Córdoba, Santiago, Wouters, Diana, Kuijpers, Taco W, Sánchez-Corral, Pilar

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Increased endoplasmic reticulum stress and decreased proteasomal function in lafora disease models lacking the phosphatase laforin von Vernia, Santiago, Rubio, Teresa, Heredia, Miguel, Rodríguez de Córdoba, Santiago, Sanz, Pascual

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Structural insights on complement activation von Alcorlo, Martín, López‐Perrote, Andrés, Delgado, Sandra, Yébenes, Hugo, Subías, Marta, Rodríguez‐Gallego, César, Rodríguez de Córdoba, Santiago, Llorca, Oscar

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Eculizumab Modifies Outcomes in Adults with Atypical Hemolytic Uremic Syndrome with Acute Kidney Injury von Cao, Mercedes, Leite, Bruna N., Ferreiro, Tamara, Calvo, María, Fernández, Constantino, Alonso, Ángel, Rodriguez, Alejandro, Salvador, Pilar, Seijo, Rocío, Pita, Salvador, Arjona, Emilia, Rodríguez de Córdoba, Santiago, Valdés Cañedo, Francisco

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3D structure of the C3bB complex provides insights into the activation and regulation of the complement alternative pathway convertase von Torreira, Eva, Tortajada, Agustín, Montes, Tamara, de Córdoba, Santiago Rodríguez, Llorca, Oscar

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Familial risk of developing atypical hemolytic-uremic syndrome von Arjona, Emilia, Huerta, Ana, Goicoechea de Jorge, Elena, Rodríguez de Córdoba, Santiago

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Eculizumab in secondary atypical haemolytic uraemic syndrome von Cavero, Teresa, Rabasco, Cristina, López, Antía, Román, Elena, Ávila, Ana, Sevillano, Ángel, Huerta, Ana, Rojas-Rivera, Jorge, Fuentes, Carolina, Blasco, Miquel, Jarque, Ana, García, Alba, Mendizabal, Santiago, Gavela, Eva, Macía, Manuel, Quintana, Luis F., María Romera, Ana, Borrego, Josefa, Arjona, Emi, Espinosa, Mario, Portolés, José, Gracia-Iguacel, Carolina, González-Parra, Emilio, Aljama, Pedro, Morales, Enrique, Cao, Mercedes, Rodríguez de Córdoba, Santiago, Praga, Manuel

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