Histone H3K27 dimethyl loss is highly specific for malignant peripheral nerve sheath tumor and distinguishes true PRC2 loss from isolated H3K27 trimethyl loss von Marchione, Dylan M., Lisby, Amanda, Viaene, Angela N., Santi, Mariarita, Nasrallah, MacLean, Wang, Li-Ping, Williams, Erik A., Larque, Ana B., Chebib, Ivan, Garcia, Benjamin A., Wojcik, John B.

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Assessment of programmed death‐ligand 1 expression and tumor‐associated immune cells in pediatric cancer tissues von Majzner, Robbie G., Simon, Jason S., Grosso, Joseph F., Martinez, Daniel, Pawel, Bruce R., Santi, Mariarita, Merchant, Melinda S., Geoerger, Birgit, Hezam, Imene, Marty, Virginie, Vielh, Phillippe, Daugaard, Mads, Sorensen, Poul H., Mackall, Crystal L., Maris, John M.

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Evaluation of Histone 3 Lysine 27 Trimethylation (H3K27me3) and Enhancer of Zest 2 (EZH2) in Pediatric Glial and Glioneuronal Tumors Shows Decreased H3K27me3 in H3F3A K27M Mutant G... von Venneti, Sriram, Garimella, Mihir T., Sullivan, Lisa M., Martinez, Daniel, Huse, Jason T., Heguy, Adriana, Santi, Mariarita, Thompson, Craig B., Judkins, Alexander R.

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Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma von Bosse, Kristopher R., Raman, Pichai, Zhu, Zhongyu, Lane, Maria, Martinez, Daniel, Heitzeneder, Sabine, Rathi, Komal S., Kendsersky, Nathan M., Randall, Michael, Donovan, Laura, Morrissy, Sorana, Sussman, Robyn T., Zhelev, Doncho V., Feng, Yang, Wang, Yanping, Hwang, Jennifer, Lopez, Gonzalo, Harenza, Jo Lynne, Wei, Jun S., Pawel, Bruce, Bhatti, Tricia, Santi, Mariarita, Ganguly, Arupa, Khan, Javed, Marra, Marco A., Taylor, Michael D., Dimitrov, Dimiter S., Mackall, Crystal L., Maris, John M.

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Inhibition of MYC attenuates tumor cell self‐renewal and promotes senescence in SMARCB1‐deficient Group 2 atypical teratoid rhabdoid tumors to suppress tumor growth in vivo von Alimova, Irina, Pierce, Angela, Danis, Etienne, Donson, Andrew, Birks, Diane K., Griesinger, Andrea, Foreman, Nicholas K., Santi, Mariarita, Soucek, Laura, Venkataraman, Sujatha, Vibhakar, Rajeev

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Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma von Coy, Shannon, Wang, Shu, Stopka, Sylwia A., Lin, Jia-Ren, Yapp, Clarence, Ritch, Cecily C., Salhi, Lisa, Baker, Gregory J., Rashid, Rumana, Baquer, Gerard, Regan, Michael, Khadka, Prasidda, Cole, Kristina A., Hwang, Jaeho, Wen, Patrick Y., Bandopadhayay, Pratiti, Santi, Mariarita, De Raedt, Thomas, Ligon, Keith L., Agar, Nathalie Y. R., Sorger, Peter K., Touat, Mehdi, Santagata, Sandro

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A sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas von Venneti, Sriram, Santi, Mariarita, Felicella, Michelle Madden, Yarilin, Dmitry, Phillips, Joanna J., Sullivan, Lisa M., Martinez, Daniel, Perry, Arie, Lewis, Peter W., Thompson, Craig B., Judkins, Alexander R.

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Genomic Analysis of Dysembryoplastic Neuroepithelial Tumor Spectrum Reveals a Diversity of Molecular Alterations Dysregulating the MAPK and PI3K/mTOR Pathways von Surrey, Lea F, Jain, Payal, Zhang, Bo, Straka, Joshua, Zhao, Xiaonan, Harding, Brian N, Resnick, Adam C, Storm, Phillip B, Buccoliero, Anna Maria, Genitori, Lorenzo, Li, Marilyn M, Waanders, Angela J, Santi, Mariarita

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Molecular and clinicopathologic features of gliomas harboring NTRK fusions von Torre, Matthew, Vasudevaraja, Varshini, Serrano, Jonathan, DeLorenzo, Michael, Malinowski, Seth, Blandin, Anne-Florence, Pages, Melanie, Ligon, Azra H., Dong, Fei, Meredith, David M., Nasrallah, MacLean P., Horbinski, Craig, Dahiya, Sonika, Ligon, Keith L., Santi, Mariarita, Ramkissoon, Shakti H., Filbin, Mariella G., Snuderl, Matija, Alexandrescu, Sanda

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Pro-inflammatory cytokines mediate the epithelial-to-mesenchymal-like transition of pediatric posterior fossa ependymoma von Aubin, Rachael G., Troisi, Emma C., Montelongo, Javier, Alghalith, Adam N., Nasrallah, Maclean P., Santi, Mariarita, Camara, Pablo G.

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Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas von Dougherty, Margaret J., Santi, Mariarita, Brose, Marcia S., Ma, Changqing, Resnick, Adam C., Sievert, Angela J., Storm, Phillip B., Biegel, Jaclyn A.

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The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: a multi-institutional stu... von Abedalthagafi, Malak, Phillips, Joanna J, Kim, Grace E, Mueller, Sabine, Haas-Kogen, Daphne A, Marshall, Roxanne E, Croul, Sidney E, Santi, Mariarita R, Cheng, Jing, Zhou, Shengmei, Sullivan, Lisa M, Martinez-Lage, Maria, Judkins, Alexander R, Perry, Arie

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Clinical utility of custom-designed NGS panel testing in pediatric tumors von Surrey, Lea F, MacFarland, Suzanne P, Chang, Fengqi, Cao, Kajia, Rathi, Komal S, Akgumus, Gozde T, Gallo, Daniel, Lin, Fumin, Gleason, Adam, Raman, Pichai, Aplenc, Richard, Bagatell, Rochelle, Minturn, Jane, Mosse, Yael, Santi, Mariarita, Tasian, Sarah K, Waanders, Angela J, Sarmady, Mahdi, Maris, John M, Hunger, Stephen P, Li, Marilyn M

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Generation of a mouse model of atypical teratoid/rhabdoid tumor of the central nervous system through combined deletion of Snf5 and p53 von Ng, Jessica M Y, Martinez, Daniel, Marsh, Eric D, Zhang, Zhe, Rappaport, Eric, Santi, Mariarita, Curran, Tom

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SMARCB1 deletion in atypical teratoid rhabdoid tumors results in human endogenous retrovirus K (HML-2) expression von Doucet-O’Hare, Tara T., DiSanza, Brianna L., DeMarino, Catherine, Atkinson, Abigail L., Rosenblum, Jared S., Henderson, Lisa J., Johnson, Kory R., Kowalak, Jeffrey, Garcia-Montojo, Marta, Allen, Sariah J., Orr, Brent A., Santi, Mariarita, Wang, Tongguang, Fathi, Saeed, Lee, Myoung Hwa, Sampson, Kevon, Li, Wenxue, Zhuang, Zhengping, Nath, Avindra

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B7–H3 as a Prognostic Biomarker and Therapeutic Target in Pediatric central nervous system Tumors von Maachani, Uday B., Tosi, Umberto, Pisapia, David J., Mukherjee, Sushmita, Marnell, Christopher S., Voronina, Julia, Martinez, Daniel, Santi, Mariarita, Dahmane, Nadia, Zhou, Zhiping, Hawkins, Cynthia, Souweidane, Mark M.

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Angiocentric glioma-associated seizures: The possible role of EATT2, pyruvate carboxylase and glutamine synthetase von Buccoliero, Anna Maria, Caporalini, Chiara, Scagnet, Mirko, Mussa, Federico, Giordano, Flavio, Sardi, Iacopo, Migliastro, Irene, Moscardi, Selene, Conti, Valerio, Barba, Carmen, Antonelli, Manila, Gianno, Francesca, Rossi, Sabrina, Diomedi-Camassei, Francesca, Gessi, Marco, Donofrio, Vittoria, Bertero, Luca, Giangaspero, Felice, Santi, Mariarita, Aronica, Eleonora, Genitori, Lorenzo, Guerrini, Renzo

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Whole Chromosome 7 Gain Predicts Higher Risk of Recurrence in Pediatric Pilocytic Astrocytomas Independently From KIAA1549-BRAF Fusion Status von Roth, Jacquelyn J., Fierst, Tamara M., Waanders, Angela J., Yimei, Li, Biegel, Jaclyn A., Santi, Mariarita

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PDGFRA Amplification is Common in Pediatric and Adult High-Grade Astrocytomas and Identifies a Poor Prognostic Group in IDH1 Mutant Glioblastoma von Phillips, Joanna J., Aranda, Derick, Ellison, David W., Judkins, Alexander R., Croul, Sidney E., Brat, Daniel J., Ligon, Keith L., Horbinski, Craig, Venneti, Sriram, Zadeh, Gelareh, Santi, Mariarita, Zhou, Shengmei, Appin, Christina L., Sioletic, Stefano, Sullivan, Lisa M., Martinez-Lage, Maria, Robinson, Aaron E., Yong, William H., Cloughesy, Timothy, Lai, Albert, Phillips, Heidi S., Marshall, Roxanne, Mueller, Sabine, Haas-Kogan, Daphne A., Molinaro, Annette M., Perry, Arie

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SETD2 mutations in primary central nervous system tumors von Viaene, Angela N, Santi, Mariarita, Rosenbaum, Jason, Li, Marilyn M, Surrey, Lea F, Nasrallah, MacLean P

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