Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo von Phesse, T J, Myant, K B, Cole, A M, Ridgway, R A, Pearson, H, Muncan, V, van den Brink, G R, Vousden, K H, Sears, R, Vassilev, L T, Clarke, A R, Sansom, O J

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Absolute requirement for STAT3 function in small-intestine crypt stem cell survival von Matthews, J R, Sansom, O J, Clarke, A R

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Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells von Huels, D. J., Bruens, L., Hodder, M. C., Cammareri, P., Campbell, A. D., Ridgway, R. A., Gay, D. M., Solar-Abboud, M., Faller, W. J., Nixon, C., Zeiger, L. B., McLaughlin, M. E., Morrissey, E., Winton, D. J., Snippert, H. J., van Rheenen, J., Sansom, O. J.

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Microenvironmental cues in cancer stemness von Flanagan, D. J., Hodder, M. C., Sansom, O. J.

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Exploiting inflammation for therapeutic gain in pancreatic cancer von Steele, C W, Jamieson, N B, Evans, T R J, McKay, C J, Sansom, O J, Morton, J P, Carter, C R

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Non-canonical Wnt signalling regulates scarring in biliary disease via the planar cell polarity receptors von Wilson, D. H., Jarman, E. J., Mellin, R. P., Wilson, M. L., Waddell, S. H., Tsokkou, P., Younger, N. T., Raven, A., Bhalla, S. R., Noll, A. T. R., Olde Damink, S. W., Schaap, F. G., Chen, P., Bates, D. O., Banales, J. M., Dean, C. H., Henderson, D. J., Sansom, O. J., Kendall, T. J., Boulter, L.

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Functions of TAp63 and p53 in restraining the development of metastatic cancer von Tan, E H, Morton, J P, Timpson, P, Tucci, P, Melino, G, Flores, E R, Sansom, O J, Vousden, K H, Muller, P A J

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Myc heterozygosity attenuates the phenotypes of APC deficiency in the small intestine von Athineos, D, Sansom, O J

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Wnt signalling and its role in stem cell-driven intestinal regeneration and hyperplasia von Cordero, J. B., Sansom, O. J.

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A RAC-GEF network critical for early intestinal tumourigenesis von Pickering, K. A., Gilroy, K., Cassidy, J. W., Fey, S. K., Najumudeen, A. K., Zeiger, L. B., Vincent, D. F., Gay, D. M., Johansson, J., Fordham, R. P., Miller, B., Clark, W., Hedley, A., Unal, E. B., Kiel, C., McGhee, E., Machesky, L. M., Nixon, C., Johnsson, A. E., Bain, M., Strathdee, D., van Hoof, S. R., Medema, J. P., Anderson, K. I., Brachmann, S. M., Stucke, V. M., Malliri, A., Drysdale, M., Turner, M., Serrano, L., Myant, K., Campbell, A. D., Sansom, O. J.

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β-Catenin activation synergizes with PTEN loss to cause bladder cancer formation von Ahmad, I, Morton, J P, Singh, L B, Radulescu, S M, Ridgway, R A, Patel, S, Woodgett, J, Winton, D J, Taketo, M M, Wu, X-R, Leung, H Y, Sansom, O J

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NFκB signalling is upregulated in a subset of castrate-resistant prostate cancer patients and correlates with disease progression von McCall, P, Bennett, L, Ahmad, I, MacKenzie, L M, Forbes, I W G, Leung, H Y, Sansom, O J, Orange, C, Seywright, M, Underwood, M A, Edwards, J

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Stem vs non-stem cell origin of colorectal cancer von Huels, D J, Sansom, O J

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Defining the role of APC in the mitotic spindle checkpoint in vivo: APC-deficient cells are resistant to Taxol von Radulescu, S, Ridgway, R A, Appleton, P, Kroboth, K, Patel, S, Woodgett, J, Taylor, S, Nathke, I S, Sansom, O J

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GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine von Ferro, R., Adamska, A., Lattanzio, R., Mavrommati, I., Edling, C. E., Arifin, S. A., Fyffe, C. A., Sala, G., Sacchetto, L., Chiorino, G., De Laurenzi, V., Piantelli, M., Sansom, O. J., Maffucci, T., Falasca, M.

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Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion von Muller, P A J, Trinidad, A G, Timpson, P, Morton, J P, Zanivan, S, van den Berghe, P V E, Nixon, C, Karim, S A, Caswell, P T, Noll, J E, Coffill, C R, Lane, D P, Sansom, O J, Neilsen, P M, Norman, J C, Vousden, K H

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Calcium signalling links MYC to NUAK1 von Monteverde, T, Tait-Mulder, J, Hedley, A, Knight, J R, Sansom, O J, Murphy, D J

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Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo von Phesse, T J, Myant, K B, Cole, A M, Ridgway, R A, Pearson, H, Muncan, V, van den Brink, G R, Vousden, K H, Sears, R, Vassilev, L T, Clarke, A R, Sansom, O J

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Absolute requirement for STAT3 function in small-intestine crypt stem cell survival von Matthews, J R, Sansom, O J, Clarke, A R

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Pancreatic Cancer: From Genome Discovery to PRECISION-Panc von Dreyer, S.B., Jamieson, N.B., Morton, J.P., Sansom, O.J., Biankin, A.V., Chang, D.K.

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