Metabolic interventions in the immune response to cancer von O’Sullivan, David, Sanin, David E., Pearce, Edward J., Pearce, Erika L.

Volltext

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming von Buck, Michael D., O’Sullivan, David, Klein Geltink, Ramon I., Curtis, Jonathan D., Chang, Chih-Hao, Sanin, David E., Qiu, Jing, Kretz, Oliver, Braas, Daniel, van der Windt, Gerritje J.W., Chen, Qiongyu, Huang, Stanley Ching-Cheng, O’Neill, Christina M., Edelson, Brian T., Pearce, Edward J., Sesaki, Hiromi, Huber, Tobias B., Rambold, Angelika S., Pearce, Erika L.

Volltext

Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function von Field, Cameron S., Baixauli, Francesc, Kyle, Ryan L., Puleston, Daniel J., Cameron, Alanna M., Sanin, David E., Hippen, Keli L., Loschi, Michael, Thangavelu, Govindarajan, Corrado, Mauro, Edwards-Hicks, Joy, Grzes, Katarzyna M., Pearce, Edward J., Blazar, Bruce R., Pearce, Erika L.

Volltext

Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing von Willenborg, Sebastian, Sanin, David E., Jais, Alexander, Ding, Xiaolei, Ulas, Thomas, Nüchel, Julian, Popović, Milica, MacVicar, Thomas, Langer, Thomas, Schultze, Joachim L., Gerbaulet, Alexander, Roers, Axel, Pearce, Edward J., Brüning, Jens C., Trifunovic, Aleksandra, Eming, Sabine A.

Volltext

Type 1 Interferons Induce Changes in Core Metabolism that Are Critical for Immune Function von Wu, Duojiao, Sanin, David E., Everts, Bart, Chen, Qiongyu, Qiu, Jing, Buck, Michael D., Patterson, Annette, Smith, Amber M., Chang, Chih-Hao, Liu, Zhiping, Artyomov, Maxim N., Pearce, Erika L., Cella, Marina, Pearce, Edward J.

Volltext

Triacylglycerol synthesis enhances macrophage inflammatory function von Castoldi, Angela, Monteiro, Lauar B., van Teijlingen Bakker, Nikki, Sanin, David E., Rana, Nisha, Corrado, Mauro, Cameron, Alanna M., Hässler, Fabian, Matsushita, Mai, Caputa, George, Klein Geltink, Ramon I., Büscher, Jörg, Edwards-Hicks, Joy, Pearce, Erika L., Pearce, Edward J.

Volltext

Acetate Promotes T Cell Effector Function during Glucose Restriction von Qiu, Jing, Villa, Matteo, Sanin, David E., Buck, Michael D., O’Sullivan, David, Ching, Reagan, Matsushita, Mai, Grzes, Katarzyna M., Winkler, Frances, Chang, Chih-Hao, Curtis, Jonathan D., Kyle, Ryan L., Van Teijlingen Bakker, Nikki, Corrado, Mauro, Haessler, Fabian, Alfei, Francesca, Edwards-Hicks, Joy, Maggi, Leonard B., Zehn, Dietmar, Egawa, Takeshi, Bengsch, Bertram, Klein Geltink, Ramon I., Jenuwein, Thomas, Pearce, Edward J., Pearce, Erika L.

Volltext

IL-10 Production in Macrophages Is Regulated by a TLR-Driven CREB-Mediated Mechanism That Is Linked to Genes Involved in Cell Metabolism von Sanin, David E, Prendergast, Catriona T, Mountford, Adrian P

Volltext

Polyamine metabolism is a central determinant of helper T cell lineage fidelity von Puleston, Daniel J., Baixauli, Francesc, Sanin, David E., Edwards-Hicks, Joy, Villa, Matteo, Kabat, Agnieszka M., Kamiński, Marcin M., Stanckzak, Michal, Weiss, Hauke J., Grzes, Katarzyna M., Piletic, Klara, Field, Cameron S., Corrado, Mauro, Haessler, Fabian, Wang, Chao, Musa, Yaarub, Schimmelpfennig, Lena, Flachsmann, Lea, Mittler, Gerhard, Yosef, Nir, Kuchroo, Vijay K., Buescher, Joerg M., Balabanov, Stefan, Pearce, Edward J., Green, Douglas R., Pearce, Erika L.

Volltext

Inflammatory macrophage dependence on NAD+ salvage is a consequence of reactive oxygen species–mediated DNA damage von Cameron, Alanna M., Castoldi, Angela, Sanin, David E., Flachsmann, Lea J., Field, Cameron S., Puleston, Daniel. J., Kyle, Ryan L., Patterson, Annette E., Hässler, Fabian, Buescher, Joerg M., Kelly, Beth, Pearce, Erika L., Pearce, Edward J.

Volltext

Mitochondrial Priming by CD28 von Klein Geltink, Ramon I, O'Sullivan, David, Corrado, Mauro, Bremser, Anna, Buck, Michael D, Buescher, Joerg M, Firat, Elke, Zhu, Xuekai, Niedermann, Gabriele, Caputa, George, Kelly, Beth, Warthorst, Ursula, Rensing-Ehl, Anne, Kyle, Ryan L, Vandersarren, Lana, Curtis, Jonathan D, Patterson, Annette E, Lawless, Simon, Grzes, Katarzyna, Qiu, Jing, Sanin, David E, Kretz, Oliver, Huber, Tobias B, Janssens, Sophie, Lambrecht, Bart N, Rambold, Angelika S, Pearce, Edward J, Pearce, Erika L

Volltext

IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals von Stanczak, Michal A., Sanin, David E., Apostolova, Petya, Nerz, Gabriele, Lampaki, Dimitrios, Hofmann, Maike, Steinmann, Daniel, Krohn-Grimberghe, Marvin, Thimme, Robert, Mittler, Gerhard, Waller, Cornelius F., Pearce, Edward J., Pearce, Erika L.

Volltext

Sm16, a major component of Schistosoma mansoni cercarial excretory/secretory products, prevents macrophage classical activation and delays antigen processing von Sanin, David E, Mountford, Adrian P

Volltext

Trained immunity of alveolar macrophages requires metabolic rewiring and type 1 interferon signaling von Zahalka, Sophie, Starkl, Philipp, Watzenboeck, Martin L., Farhat, Asma, Radhouani, Mariem, Deckert, Florian, Hladik, Anastasiya, Lakovits, Karin, Oberndorfer, Felicitas, Lassnig, Caroline, Strobl, Birgit, Klavins, Kristaps, Matsushita, Mai, Sanin, David E., Grzes, Katarzyna M., Pearce, Edward J., Gorki, Anna-Dorothea, Knapp, Sylvia

Volltext

Sulfur sequestration promotes multicellularity during nutrient limitation von Kelly, Beth, Carrizo, Gustavo E., Edwards-Hicks, Joy, Sanin, David E., Stanczak, Michal A., Priesnitz, Chantal, Flachsmann, Lea J., Curtis, Jonathan D., Mittler, Gerhard, Musa, Yaarub, Becker, Thomas, Buescher, Joerg M., Pearce, Erika L.

Volltext

FADD- and RIPK3-Mediated Cell Death Ensures Clearance of Ly6Chigh Wound Macrophages from Damaged Tissue von Injarabian, Louise, Willenborg, Sebastian, Welcker, Daniela, Sanin, David E., Pasparakis, Manolis, Kashkar, Hamid, Eming, Sabine A.

Volltext

Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through MYC von Sena, Laura A, Kumar, Rajendra, Sanin, David E, Thompson, Elizabeth A, Rosen, D Marc, Dalrymple, Susan L, Antony, Lizamma, Yang, Yuhan, Gomes-Alexandre, Carolina, Hicks, Jessica L, Jones, Tracy, Bowers, Kiara A, Eskra, Jillian N, Meyers, Jennifer, Gupta, Anuj, Skaist, Alyza, Yegnasubramanian, Srinivasan, Luo, Jun, Brennen, W Nathaniel, Kachhap, Sushant K, Antonarakis, Emmanuel S, De Marzo, Angelo M, Isaacs, John T, Markowski, Mark C, Denmeade, Samuel R

Volltext

An LKB1–mitochondria axis controls TH17 effector function von Baixauli, Francesc, Piletic, Klara, Puleston, Daniel J., Villa, Matteo, Field, Cameron S., Flachsmann, Lea J., Quintana, Andrea, Rana, Nisha, Edwards-Hicks, Joy, Matsushita, Mai, Stanczak, Michal A., Grzes, Katarzyna M., Kabat, Agnieszka M., Fabri, Mario, Caputa, George, Kelly, Beth, Corrado, Mauro, Musa, Yaarub, Duda, Katarzyna J., Mittler, Gerhard, O’Sullivan, David, Sesaki, Hiromi, Jenuwein, Thomas, Buescher, Joerg M., Pearce, Edward J., Sanin, David E., Pearce, Erika L.

Volltext

Plasmacytoid dendritic cell activation is dependent on coordinated expression of distinct amino acid transporters von Grzes, Katarzyna M., Sanin, David E., Kabat, Agnieszka M., Stanczak, Michal A., Edwards-Hicks, Joy, Matsushita, Mai, Hackl, Alexandra, Hässler, Fabian, Knoke, Kristin, Zahalka, Sophie, Villa, Matteo, Kofler, David M., Voll, Reinhard E., Zigrino, Paola, Fabri, Mario, Pearce, Erika L., Pearce, Edward J.

Volltext

Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment von Villa, Matteo, Sanin, David E., Apostolova, Petya, Corrado, Mauro, Kabat, Agnieszka M., Cristinzio, Carmine, Regina, Annamaria, Carrizo, Gustavo E., Rana, Nisha, Stanczak, Michal A., Baixauli, Francesc, Grzes, Katarzyna M., Cupovic, Jovana, Solagna, Francesca, Hackl, Alexandra, Globig, Anna-Maria, Hässler, Fabian, Puleston, Daniel J., Kelly, Beth, Cabezas-Wallscheid, Nina, Hasselblatt, Peter, Bengsch, Bertram, Zeiser, Robert, Sagar, Buescher, Joerg M., Pearce, Edward J., Pearce, Erika L.

Volltext