Pipeline Transportation of Heavy Oils, a Strategic, Economic and Technological Challenge von Saniere, A., Hénaut, I., Argillier, J. F.

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Pipeline transportation of heavy oils, a strategic, economic and technological challenge : Pipeline transportation of heavy oils von SANIERE, A, HENAUT, I, ARGILLIER, J. F

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Discovery of 9‑Cyclopropylethynyl-2-((S)‑1-[1,4]dioxan-2-ylmethoxy)-6,7-dihydropyrimido[6,1‑a]­isoquinolin-4-one (GLPG1205), a Unique GPR84 Negative Allosteric Modulator Undergoing... von Labéguère, Frédéric, Dupont, Sonia, Alvey, Luke, Soulas, Florilène, Newsome, Gregory, Tirera, Amynata, Quenehen, Vanessa, Mai, Thi Thu Trang, Deprez, Pierre, Blanqué, Roland, Oste, Line, Le Tallec, Sandrine, De Vos, Steve, Hagers, Annick, Vandevelde, Ann, Nelles, Luc, Vandervoort, Nele, Conrath, Katja, Christophe, Thierry, van der Aar, Ellen, Wakselman, Emanuelle, Merciris, Didier, Cottereaux, Céline, da Costa, Cécile, Saniere, Laurent, Clement-Lacroix, Philippe, Jenkins, Laura, Milligan, Graeme, Fletcher, Stephen, Brys, Reginald, Gosmini, Romain

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Discovery and Optimization of an Azetidine Chemical Series As a Free Fatty Acid Receptor 2 (FFA2) Antagonist: From Hit to Clinic von Pizzonero, Mathieu, Dupont, Sonia, Babel, Marielle, Beaumont, Stéphane, Bienvenu, Natacha, Blanqué, Roland, Cherel, Laëtitia, Christophe, Thierry, Crescenzi, Benedetta, De Lemos, Elsa, Delerive, Philippe, Deprez, Pierre, De Vos, Steve, Djata, Fatoumata, Fletcher, Stephen, Kopiejewski, Sabrina, L’Ebraly, Christelle, Lefrançois, Jean-Michel, Lavazais, Stéphanie, Manioc, Murielle, Nelles, Luc, Oste, Line, Polancec, Denis, Quénéhen, Vanessa, Soulas, Florilène, Triballeau, Nicolas, van der Aar, Ellen M, Vandeghinste, Nick, Wakselman, Emanuelle, Brys, Reginald, Saniere, Laurent

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The Medium-Chain Fatty Acid Receptor GPR84 Mediates Myeloid Cell Infiltration Promoting Steatohepatitis and Fibrosis von Puengel, Tobias, De Vos, Steve, Hundertmark, Jana, Kohlhepp, Marlene, Guldiken, Nurdan, Pujuguet, Philippe, Auberval, Marielle, Marsais, Florence, Shoji, Kenji F, Saniere, Laurent, Trautwein, Christian, Luedde, Tom, Strnad, Pavel, Brys, Reginald, Clément-Lacroix, Philippe, Tacke, Frank

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Pharmacological targeting of the ephrin receptor kinase signalling by GLPG1790 in vitro and in vivo reverts oncophenotype, induces myogenic differentiation and radiosensitizes embr... von Megiorni, Francesca, Gravina, Giovanni Luca, Camero, Simona, Ceccarelli, Simona, Del Fattore, Andrea, Desiderio, Vincenzo, Papaccio, Federica, McDowell, Heather P, Shukla, Rajeev, Pizzuti, Antonio, Beirinckx, Filip, Pujuguet, Philippe, Saniere, Laurent, der Aar, Ellen Van, Maggio, Roberto, De Felice, Francesca, Marchese, Cinzia, Dominici, Carlo, Tombolini, Vincenzo, Festuccia, Claudio, Marampon, Francesco

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Discovery of the S1P2 Antagonist GLPG2938 (1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a Precli... von Mammoliti, Oscar, Palisse, Adeline, Joannesse, Caroline, El Bkassiny, Sandy, Allart, Brigitte, Jaunet, Alex, Menet, Christel, Coornaert, Beatrice, Sonck, Kathleen, Duys, Inge, Clément-Lacroix, Philippe, Oste, Line, Borgonovi, Monica, Wakselman, Emanuelle, Christophe, Thierry, Houvenaghel, Nicolas, Jans, Mia, Heckmann, Bertrand, Sanière, Laurent, Brys, Reginald

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Discovery and Optimization of Orally Bioavailable Phthalazone and Cinnolone Carboxylic Acid Derivatives as S1P2 Antagonists against Fibrotic Diseases von Mammoliti, Oscar, Jansen, Koen, El Bkassiny, Sandy, Palisse, Adeline, Triballeau, Nicolas, Bucher, Denis, Allart, Brigitte, Jaunet, Alex, Tricarico, Giovanni, De Wachter, Maxim, Menet, Christel, Blanc, Javier, Letfus, Vatroslav, Rupčić, Renata, Šmehil, Mario, Poljak, Tanja, Coornaert, Beatrice, Sonck, Kathleen, Duys, Inge, Waeckel, Ludovic, Lecru, Lola, Marsais, Florence, Jagerschmidt, Catherine, Auberval, Marielle, Pujuguet, Philippe, Oste, Line, Borgonovi, Monica, Wakselman, Emanuelle, Christophe, Thierry, Houvenaghel, Nicolas, Jans, Mia, Heckmann, Bertrand, Sanière, Laurent, Brys, Reginald

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Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics in human lung fibrogenesis von Lang, Niklas J, Gote-Schniering, Janine, Porras-Gonzalez, Diana, Yang, Lin, De Sadeleer, Laurens J, Jentzsch, R. Christoph, Shitov, Vladimir A, Zhou, Shuhong, Ansari, Meshal, Agami, Ahmed, Mayr, Christoph H, Hooshiar Kashani, Baharak, Chen, Yuexin, Heumos, Lukas, Pestoni, Jeanine C, Molnar, Eszter Sarolta, Geeraerts, Emiel, Anquetil, Vincent, Saniere, Laurent, Woegrath, Melanie, Gerckens, Michael, Lehmann, Mareike, Yildirim, Ali Onder, Hatz, Rudolf, Kneidinger, Nikolaus, Behr, Juergen, Wuyts, Wim A, Stoleriu, Mircea-Gabriel, Luecken, Malte D, Theis, Fabian J, Burgstaller, Gerald, Schiller, Herbert B

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Reinvestigation of the Branimycin Stereochemistry at Position 17‑C von Čikoš, Ana, Triballeau, Nicolas, Hubbard, Paul A, Žiher, Dinko, Stouten, Pieter F. W, Doyon, Julien G. P.-O, Deschrijver, Tiny, Wouters, Johan, Lépine, Renaud H. M, Saniere, Laurent

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The Small Molecule Ephrin Receptor Inhibitor, GLPG1790, Reduces Renewal Capabilities of Cancer Stem Cells, Showing Anti-Tumour Efficacy on Preclinical Glioblastoma Models von Gravina, Giovanni Luca, Mancini, Andrea, Colapietro, Alessandro, Delle Monache, Simona, Sferra, Roberta, Vitale, Flora, Cristiano, Loredana, Martellucci, Stefano, Marampon, Francesco, Mattei, Vincenzo, Beirinckx, Filip, Pujuguet, Philippe, Saniere, Laurent, Lorenzon, Giocondo, van der Aar, Ellen, Festuccia, Claudio

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THU-461 - Pharmacological inhibition of the medium chain fatty acid receptor GPR84 reduces myeloid cell in filtration into injured liver and ameliorates steatohepatitis and fibrosi... von Puengel, T., De Vos, S., Krenkel, O., Pujuguet, P., Auberval, M., Marsais, F., Shoji, K.F., Saniere, L., Trautwein, C., Brys, R., Tacke, F.

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Pharmacological inhibition of the medium chain fatty acid receptor GPR84 reduces myeloid cell in filtration into injured liver and ameliorates steatohepatitis and fibrosis von Puengel, T., De Vos, S., Krenkel, O., Pujuguet, P., Auberval, M., Marsais, F., Shoji, K.F., Saniere, L., Trautwein, C., Brys, R., Tacke, F.

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Antitumorigenic Effects of Inhibiting Ephrin Receptor Kinase Signaling by GLPG1790 against Colorectal Cancer Cell Lines In Vitro and In Vivo von Van der Aar, Ellen, Musio, Daniela, Mattei, Vincenzo, Martellucci, Stefano, Maggio, Roberto, Tombolini, Vincenzo, Festuccia, Claudio, Marampon, Francesco, Saniere, Laurent, Pujuguet, Philippe, Beirinckx, Filip, Scicchitano, Bianca Maria, Fasciani, Irene, Petragnano, Francesco, Gravina, Giovanni Luca, Colapietro, Alessandro, De Felice, Francesca

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Copper-Catalyzed Nitrogen Transfer Mediated by Iodosylbenzene PhIO von Dauban, Philippe, Sanière, Laurent, Tarrade, Aurélie, Dodd, Robert H

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Abstract 1753: GLPG1790: The first Ephrin (EPH) receptor tyrosine kinase inhibitor for the treatment of triple negative breast cancer von Pujuguet, Philippe, Beirinckx, Filip, Delachaume, Carole, Huck, Jacques, Aar, Ellen Van der, Brys, Reginald, Rompaey, Luc Van, Wigerinck, Piet, Saniere, Laurent

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Les sciences sociales et la société. Nouveaux lieux, discours et pratiques de la diversité et de la citoyenneté von Calenda

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Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors von Rankovic, Zoran, Cai, Jiaqiang, Kerr, Jennifer, Fradera, Xavier, Robinson, John, Mistry, Ashvin, Hamilton, Emma, McGarry, George, Andrews, Fiona, Caulfield, Wilson, Cumming, Iain, Dempster, Maureen, Waller, John, Scullion, Paul, Martin, Iain, Mitchell, Ann, Long, Clive, Baugh, Mark, Westwood, Paul, Kinghorn, Emma, Bruin, John, Hamilton, William, Uitdehaag, Joost, Zeeland, Mario van, Potin, Dominique, Saniere, Laurent, Fouquet, Andre, Chevallier, François, Deronzier, Hortense, Dorleans, Cecile, Nicolai, Eric

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2-Phenyl-9H-purine-6-carbonitrile derivatives as selective cathepsin S inhibitors von Cai, Jiaqiang, Bennett, D. Jonathan, Rankovic, Zoran, Dempster, Maureen, Fradera, Xavier, Gillespie, Jonathan, Cumming, Iain, Finlay, William, Baugh, Mark, Boucharens, Sylviane, Bruin, John, Cameron, Kenneth S., Hamilton, William, Kerr, Jennifer, Kinghorn, Emma, McGarry, George, Robinson, John, Scullion, Paul, Uitdehaag, Joost C.M., van Zeeland, Mario, Potin, Dominique, Saniere, Laurent, Fouquet, Andre, Chevallier, Francois, Deronzier, Hortense, Dorleans, Cecile, Nicolai, Eric

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Copper-catalyzed aziridination of allylglycine derivatives von Leman, Loic, Saniere, Laurent, Dauban, Philippe, Dodd, Robert H.

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