Purification of Fluorous Mitsunobu Reactions by Liquid-Liquid Extraction von Curran, Dennis P., Bajpai, Reena, Sanger, Elizabeth

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REGULATED RELEASE OF HYPER-PHOSPHORYLATED, AGGREGATED AND SEEDING COMPETENT TAU FROM RODENT BRAINS AND HUMAN SYNAPTOSOMES von Sher, Emanuele, Mazzo, Francesca, Hutton, MIchael, O'Neill, Michael J., Bose, Suchira, Kerridge, Caroline, Murray, Tracey K., Grubisha, Olivera, Ursu, Daniel, Broad, Lisa, Sanger, Helen Elizabeth, Wang, Yaming, Pan, Feng, Monn, James, Witkin, Jeffrey M., Li, Xia, Schiavo, Giampietro, Goedert, Michel

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Exhibitions: RURIK KALLIS von Sanger, Elizabeth

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Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes von White, Jacqueline K., Gerdin, Anna-Karin, Karp, Natasha A., Ryder, Ed, Bussell, James N., Salisbury, Jennifer, Clare, Simon, Ingham, Neil J., Podrini, Christine, Houghton, Richard, Estabel, Jeanne, Bottomley, Joanna R., Melvin, David G., Sunter, David, Barnes, Caroline, Cambridge, Emma, Carragher, Damian, Chana, Prabhjoat, Clarke, Kay, Igosheva, Natalia, Ismail, Ozama, Jackson, Hannah, Kane, Leanne, Lacey, Rosalind, Lucas, Mark, McGill, Katherine, McIntyre, Rebecca E., Messager, Sophie, Mottram, Lynda, Mulderrig, Lee, Pearson, Selina, Roberson, Laura-Anne, Salsbury, Grace, Sanger, Daniel, Shannon, Carl, Thompson, Paul C., Tuck, Elizabeth, Bushell, Wendy, Cook, Ross, Dalvi, Priya, Gleeson, Diane, Habib, Bishoy, Hardy, Matt, Miklejewska, Evelina, Price, Stacey, Sethi, Debarati, von Schiller, Dominique, Vyas, Sapna, West, Anthony P., Evans, Arthur, Holroyd, Simon, Iyer, Vivek, Lewis, Morag, Oakley, Darren, Richardson, David, Smedley, Damian, Agu, Chukwuma, Bryant, Jackie, Delaney, Liz, Gueorguieva, Nadia I., Tharagonnet, Helen, Townsend, Anne J., Biggs, Daniel, Collinson, Adam, Dumeau, Charles-Etienne, Grau, Evelyn, Harrison, Sarah, Ingle, Catherine E., Kundi, Helen, Madich, Alla, Mayhew, Danielle, Metcalf, Tom, Pass, Johanna, Reynolds, Helen, Sinclair, Caroline, Wardle-Jones, Hannah, Woods, Michael, Alexander, Liam, Brown, Terry, Flack, Francesca, Griggs, Nicola, McDermott, Jordan, Rogerson, Claire, White, Gemma, Zielezinski, Pawel, DiTommaso, Tia, Edwards, Andrew, Mahajan, Mary Ann, Yalcin, Binnaz, Tannahill, David, Logan, Darren W., MacArthur, Daniel G., Flint, Jonathan, Mahajan, Vinit B., Smyth, Ian, Watt, Fiona M., Skarnes, William C., Dougan, Gordon, Adams, David J., Bradley, Allan

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Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome von Balmus, Gabriel, Larrieu, Delphine, Barros, Ana C., Collins, Casey, Abrudan, Monica, Demir, Mukerrem, Geisler, Nicola J., Lelliott, Christopher J., White, Jacqueline K., Karp, Natasha A., Atkinson, James, Kirton, Andrea, Jacobsen, Matt, Clift, Dean, Rodriguez, Raphael, Adams, David J., Jackson, Stephen P.

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Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen von Menden, Michael P., Wang, Dennis, Mason, Mike J., Szalai, Bence, Bulusu, Krishna C., Guan, Yuanfang, Yu, Thomas, Kang, Jaewoo, Jeon, Minji, Wolfinger, Russ, Nguyen, Tin, Zaslavskiy, Mikhail, Jang, In Sock, Ghazoui, Zara, Ahsen, Mehmet Eren, Vogel, Robert, Neto, Elias Chaibub, Norman, Thea, Tang, Eric K. Y., Garnett, Mathew J., Veroli, Giovanni Y. Di, Fawell, Stephen, Stolovitzky, Gustavo, Guinney, Justin, Dry, Jonathan R., Saez-Rodriguez, Julio

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Genome-wide in vivo screen identifies novel host regulators of metastatic colonization von van der Weyden, Louise, Arends, Mark J., Campbell, Andrew D., Bald, Tobias, Wardle-Jones, Hannah, Griggs, Nicola, Velasco-Herrera, Martin Del Castillo, Tüting, Thomas, Sansom, Owen J., Karp, Natasha A., Clare, Simon, Gleeson, Diane, Ryder, Edward, Galli, Antonella, Tuck, Elizabeth, Cambridge, Emma L., Voet, Thierry, Macaulay, Iain C., Wong, Kim, Spiegel, Sarah, Speak, Anneliese O., Adams, David J.

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WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy von Kannan, Meghna, Bayam, Efil, Wagner, Christel, Rinaldi, Bruno, Kretz, Perrine F., Tilly, Peggy, Roos, Marna, McGillewie, Lara, Bär, Séverine, Minocha, Shilpi, Chevalier, Claire, Po, Chrystelle, Project, Sanger Mouse Genetics, Chelly, Jamel, Mandel, Jean-Louis, Borgatti, Renato, Piton, Amélie, Kinnear, Craig, Loos, Ben, Adams, David J., Hérault, Yann, Collins, Stephan C., Friant, Sylvie, Godin, Juliette D., Yalcin, Binnaz

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Genetic determinants of micronucleus formation in vivo von Adams, D. J., Barlas, B., McIntyre, R. E., Salguero, I., van der Weyden, L., Barros, A., Vicente, J. R., Karimpour, N., Haider, A., Ranzani, M., Turner, G., Thompson, N. A., Harle, V., Olvera-León, R., Robles-Espinoza, C. D., Speak, A. O., Geisler, N., Weninger, W. J., Geyer, S. H., Hewinson, J., Karp, N. A., Fu, B., Yang, F., Kozik, Z., Choudhary, J., Yu, L., van Ruiten, M. S., Rowland, B. D., Lelliott, C. J., del Castillo Velasco-Herrera, M., Verstraten, R., Bruckner, L., Henssen, A. G., Rooimans, M. A., de Lange, J., Mohun, T. J., Arends, M. J., Kentistou, K. A., Coelho, P. A., Zhao, Y., Zecchini, H., Perry, J. R. B., Jackson, S. P., Balmus, G.

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The role of sphingosine-1-phosphate transporter Spns2 in immune system function von Nijnik, Anastasia, Clare, Simon, Hale, Christine, Chen, Jing, Raisen, Claire, Mottram, Lynda, Lucas, Mark, Estabel, Jeanne, Ryder, Edward, Adissu, Hibret, Adams, Niels C, Ramirez-Solis, Ramiro, White, Jacqueline K, Steel, Karen P, Dougan, Gordon, Hancock, Robert E W

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Genomic reconstruction of the SARS-CoV-2 epidemic in England von Vöhringer, Harald S., Sanderson, Theo, Sinnott, Matthew, De Maio, Nicola, Nguyen, Thuy, Goater, Richard, Schwach, Frank, Harrison, Ian, Hellewell, Joel, Ariani, Cristina V., Gonçalves, Sonia, Jackson, David K., Johnston, Ian, Jung, Alexander W., Saint, Callum, Sillitoe, John, Suciu, Maria, Goldman, Nick, Panovska-Griffiths, Jasmina, Birney, Ewan, Volz, Erik, Funk, Sebastian, Kwiatkowski, Dominic, Chand, Meera, Martincorena, Inigo, Barrett, Jeffrey C., Gerstung, Moritz

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Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen von Adissu, Hibret A, Estabel, Jeanne, Sunter, David, Tuck, Elizabeth, Hooks, Yvette, Carragher, Damian M, Clarke, Kay, Karp, Natasha A, Newbigging, Susan, Jones, Nora, Morikawa, Lily, White, Jacqueline K, McKerlie, Colin

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High-throughput discovery of novel developmental phenotypes von Dickinson, Mary E., Flenniken, Ann M., Ji, Xiao, Teboul, Lydia, Wong, Michael D., White, Jacqueline K., Meehan, Terrence F., Weninger, Wolfgang J., Westerberg, Henrik, Adissu, Hibret, Baker, Candice N., Bower, Lynette, Brown, James M., Caddle, L. Brianna, Chiani, Francesco, Clary, Dave, Cleak, James, Daly, Mark J., Denegre, James M., Doe, Brendan, Dolan, Mary E., Edie, Sarah M., Fuchs, Helmut, Gailus-Durner, Valerie, Galli, Antonella, Gambadoro, Alessia, Gallegos, Juan, Guo, Shiying, Horner, Neil R., Hsu, Chih-Wei, Johnson, Sara J., Kalaga, Sowmya, Keith, Lance C., Lanoue, Louise, Lawson, Thomas N., Lek, Monkol, Mark, Manuel, Marschall, Susan, Mason, Jeremy, McElwee, Melissa L., Newbigging, Susan, Nutter, Lauryl M. J., Peterson, Kevin A., Ramirez-Solis, Ramiro, Rowland, Douglas J., Ryder, Edward, Samocha, Kaitlin E., Seavitt, John R., Selloum, Mohammed, Szoke-Kovacs, Zsombor, Tamura, Masaru, Trainor, Amanda G., Tudose, Ilinca, Wakana, Shigeharu, Warren, Jonathan, Wendling, Olivia, West, David B., Wong, Leeyean, Yoshiki, Atsushi, Wurst, Wolfgang, MacArthur, Daniel G., Tocchini-Valentini, Glauco P., Gao, Xiang, Flicek, Paul, Bradley, Allan, Skarnes, William C., Justice, Monica J., Parkinson, Helen E., Moore, Mark, Wells, Sara, Braun, Robert E., Svenson, Karen L., de Angelis, Martin Hrabe, Herault, Yann, Mohun, Tim, Mallon, Ann-Marie, Henkelman, R. Mark, Brown, Steve D. M., Adams, David J., Lloyd, K. C. Kent, McKerlie, Colin, Beaudet, Arthur L., Bućan, Maja, Murray, Stephen A.

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Recovery, rehabilitation and follow-up services following critical illness: an updated UK national cross-sectional survey and progress report von Connolly, Bronwen, Milton-Cole, Rhian, Adams, Claire, Battle, Ceri, McPeake, Joanne, Quasim, Tara, Silversides, Jon, Slack, Andrew, Waldmann, Carl, Wilson, Elizabeth, Meyer, Joel, Waldmann, Carl, Meyer, Joel, Slack, Andrew, Barton, Greg, Bastin, Anthony, Bear, Danielle, Bench, Suzanne, Davies, Martin, Ferguson, Andrew, Firshmann, Penny, Gager, Melanie, Highfield, Julie, Linford, Sarah, McPeake, Joanne, Merriweather, Judith, Parry-Jones, Jack, Phillips, Margaret, Quasim, Tara, Sanger, Helen, Sturmey, Gordon, Wade, Dorothy, Wilson, Elizabeth

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The genome sequence of the little shaggy moss, Rhytidiadelphus loreus (Hedw.) Warnst. (Hylocomiaceae) von Bell, David, Kungu, Elizabeth

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Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons von Li, Hongmei, Chen, Yingbei, Jones, Adrienne F, Sanger, Richard H, Collis, Leon P, Flannery, Richard, McNay, Ewan C, Yu, Tingxi, Schwarzenbacher, Robert, Bossy, Blaise, Bossy-Wetzel, Ella, Bennett, Michael V.L, Pypaert, Marc, Hickman, John A, Smith, Peter J.S, Hardwick, J. Marie, Jonas, Elizabeth A

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Downregulation of Death-Associated Protein Kinase 1 (DAPK1) in Chronic Lymphocytic Leukemia von Raval, Aparna, Tanner, Stephan M., Byrd, John C., Angerman, Elizabeth B., Perko, James D., Chen, Shih-Shih, Hackanson, Björn, Grever, Michael R., Lucas, David M., Matkovic, Jennifer J., Lin, Thomas S., Kipps, Thomas J., Murray, Fiona, Weisenburger, Dennis, Sanger, Warren, Lynch, Jane, Watson, Patrice, Jansen, Mary, Yoshinaga, Yuko, Rosenquist, Richard, de Jong, Pieter J., Coggill, Penny, Beck, Stephan, Lynch, Henry, de la Chapelle, Albert, Plass, Christoph

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Recommendations for Maintaining a Dermestid Beetle Colony (Dermestes maculatus) for Processing Human Remains von Sanger Ciarleglio, Jessica E., Perez, Kristen M., Motola, Haley L., DiGangi, Elizabeth A.

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The genome sequence of the smooth giant clam, Tridacna derasa Röding, 1798 von Li, Ruiqi, Li, Jingchun, Lopez, Jose Victor, Oatley, Graeme, Clayton-Lucey, Isabelle Ailish, Sinclair, Elizabeth, Aunin, Eerik, Gettle, Noah, Santos, Camilla, Paulini, Michael, Niu, Haoyu, McKenna, Victoria, O’Brien, Rebecca

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The genome sequence of the heart cockle, Fragum sueziense (Issel, 1869) von Li, Ruiqi, Li, Jingchun, Lemer, Sarah, Lopez, Jose Victor, Oatley, Graeme, Sinclair, Elizabeth, Clayton-Lucey, Isabelle Ailish, Aunin, Eerik, Gettle, Noah, Santos, Camilla, Paulini, Michael, Niu, Haoyu, McKenna, Victoria, O'Brien, Rebecca

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