Combined Flt3L/TK Gene Therapy Induces Immunological Surveillance Which Mediates an Immune Response Against a Surrogate Brain Tumor Neoantigen von King, Gwendalyn D, Muhammad, AKM Ghulam, Larocque, Daniel, Kelson, Kyle R, Xiong, Weidong, Liu, Chunyan, Sanderson, Nicholas SR, Kroeger, Kurt M, Castro, Maria G, Lowenstein, Pedro R

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Anti-MOG antibodies are present in a subgroup of patients with a neuromyelitis optica phenotype von Pröbstel, Anne-Katrin, Rudolf, Gabrielle, Dornmair, Klaus, Collongues, Nicolas, Chanson, Jean-Baptiste, Sanderson, Nicholas S R, Lindberg, Raija L P, Kappos, Ludwig, de Seze, Jérôme, Derfuss, Tobias

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Cocapture of cognate and bystander antigens can activate autoreactive B cells von Sanderson, Nicholas S. R., Zimmermann, Maria, Eilinger, Luca, Gubser, Céline, Schaeren-Wiemers, Nicole, Lindberg, Raija L. P., Dougan, Stephanie K., Ploegh, Hidde L., Kappos, Ludwig, Derfuss, Tobias

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Exogenous fms-like tyrosine kinase 3 ligand overrides brain immune privilege and facilitates recognition of a neo-antigen without causing autoimmune neuropathology von Larocque, Daniel, Sanderson, Nicholas S R, Bergeron, Josée, Curtin, James F, Girton, Joe, Wibowo, Mia, Bondale, Niyati, Kroeger, Kurt M, Yang, Jieping, Lacayo, Liliana M, Reyes, Kevin C, Farrokhi, Catherine, Pechnick, Robert N, Castro, Maria G, Lowenstein, Pedro R

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Abstract 4798: Cytotoxic T cells kill tumor cells in a contact and antigen-dependent manner, but the interaction affects neighboring, non-target cells via interferon gamma secretio... von Sanderson, Nicholas SR, Puntel, Mariana, Baker, Greg, Castro, Maria G., Lowenstein, Pedro R.

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IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes von Momozawa, Yukihide, Dmitrieva, Julia, Théâtre, Emilie, Deffontaine, Valérie, Rahmouni, Souad, Charloteaux, Benoît, Crins, François, Docampo, Elisa, Elansary, Mahmoud, Gori, Ann-Stephan, Lecut, Christelle, Mariman, Rob, Mni, Myriam, Oury, Cécile, Altukhov, Ilya, Alexeev, Dmitry, Aulchenko, Yuri, Amininejad, Leila, Bouma, Gerd, Hoentjen, Frank, Löwenberg, Mark, Oldenburg, Bas, Pierik, Marieke J., vander Meulen-de Jong, Andrea E., Janneke van der Woude, C., Visschedijk, Marijn C., Lathrop, Mark, Hugot, Jean-Pierre, Weersma, Rinse K., De Vos, Martine, Franchimont, Denis, Vermeire, Severine, Kubo, Michiaki, Louis, Edouard, Georges, Michel

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Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease von Jostins, Luke, Ripke, Stephan, Weersma, Rinse K., Duerr, Richard H., McGovern, Dermot P., Hui, Ken Y., Lee, James C., Philip Schumm, L., Sharma, Yashoda, Anderson, Carl A., Mitrovic, Mitja, Ning, Kaida, Cleynen, Isabelle, Theatre, Emilie, Raychaudhuri, Soumya, Goyette, Philippe, Wei, Zhi, Abraham, Clara, Achkar, Jean-Paul, Ahmad, Tariq, Amininejad, Leila, Ananthakrishnan, Ashwin N., Andersen, Vibeke, Andrews, Jane M., Baidoo, Leonard, Balschun, Tobias, Bampton, Peter A., Bitton, Alain, Boucher, Gabrielle, Brand, Stephan, Büning, Carsten, Cohain, Ariella, Cichon, Sven, D’Amato, Mauro, De Jong, Dirk, Dubinsky, Marla, Edwards, Cathryn, Ellinghaus, David, Ferguson, Lynnette R., Franchimont, Denis, Fransen, Karin, Gearry, Richard, Georges, Michel, Gieger, Christian, Glas, Jürgen, Haritunians, Talin, Hart, Ailsa, Hawkey, Chris, Hedl, Matija, Hu, Xinli, Karlsen, Tom H., Kupcinskas, Limas, Kugathasan, Subra, Latiano, Anna, Laukens, Debby, Lawrance, Ian C., Lees, Charlie W., Louis, Edouard, Mahy, Gillian, Mansfield, John, Morgan, Angharad R., Mowat, Craig, Newman, William, Palmieri, Orazio, Ponsioen, Cyriel Y., Potocnik, Uros, Prescott, Natalie J., Rotter, Jerome I., Sanderson, Jeremy D., Sans, Miquel, Schreiber, Stefan, Simms, Lisa A., Sventoraityte, Jurgita, Targan, Stephan R., Taylor, Kent D., Tremelling, Mark, Verspaget, Hein W., De Vos, Martine, Wijmenga, Cisca, Wilson, David C., Winkelmann, Juliane, Xavier, Ramnik J., Zeissig, Sebastian, Zhang, Bin, Zhang, Clarence K., Zhao, Hongyu, Silverberg, Mark S., Annese, Vito, Hakonarson, Hakon, Brant, Steven R., Radford-Smith, Graham, Mathew, Christopher G., Rioux, John D., Schadt, Eric E., Daly, Mark J., Franke, Andre, Parkes, Miles, Vermeire, Severine, Barrett, Jeffrey C., Cho, Judy H

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Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 von Anderson, CA, Boucher, G, Lees, CW, Franke, A, D'Amato, M, Taylor, KD, Lee, JC, Latiano, A, Lagace, C, Scott, R, Amininejad, L, Bumpstead, S, Baidoo, L, Baldassano, RN, Barclay, M, Bayless, TM, Brand, S, Buning, C, Colombel, JF, Denson, LA, De Vos, M, Dubinsky, M, Edwards, C, Fehrmann, RSN, Floyd, JAB, Florin, T, Georges, M, Glas, J, Glazer, NL, Guthery, SL, Haritunians, T, Hayward, NK, Hugot, JP, Laukens, D, Lawrance, I, Levine, A, Libioulle, C, Louis, E, McGovern, DP, Milla, M, Montgomery, GW, Mowat, C, Ng, A, Ophoff, RA, Papi, L, Palmieri, O, Peyrin-Biroulet, L, Panes, J, Phillips, A, Prescott, NJ, Proctor, DD, Roberts, R, Russell, R, Rutgeerts, P, Sanderson, J, Sans, M, Schumm, P, Seibold, F, Sharma, Y, Simms, LA, Seielstad, M, Steinhart, AH, Targan, SR, van den Berg, LH, Vatn, M, Verspaget, H, Walters, T, Wijmenga, C, Wilson, DC, Westra, HJ, Xavier, RJ, Zhao, ZZ, Ponsioen, CY, Andersen, V, Torkvist, L, Gazouli, M, Anagnou, NP, Karlsen, TH, Kupcinskas, L, Sventoraityte, J, Kugathasan, S, Silverberg, MS, Halfvarson, J, Mathew, CG, Griffiths, AM, Gearry, R, Ahmad, T, Brant, SR, Chamaillard, M, Cho, JH, Schreiber, S, Daly, MJ, Barrett, JC, Parkes, M, Annese, V, Hakonarson, H, Radford-Smith, G, Duerr, RH, Vermeire, S, Rioux, JD

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