Molecular characterization of mutant TP53 acute myeloid leukemia and high-risk myelodysplastic syndrome von Grob, Tim, Al Hinai, Adil S.A., Sanders, Mathijs A., Kavelaars, François G., Rijken, Melissa, Gradowska, Patrycja L., Biemond, Bart J., Breems, Dimitri A., Maertens, Johan, van Marwijk Kooy, Marinus, Pabst, Thomas, de Weerdt, Okke, Ossenkoppele, Gert J., van de Loosdrecht, Arjan A., Huls, Gerwin A., Cornelissen, Jan J., Beverloo, H. Berna, Löwenberg, Bob, Jongen-Lavrencic, Mojca, Valk, Peter J.M.

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MLL-AF9 Expression in Hematopoietic Stem Cells Drives a Highly Invasive AML Expressing EMT-Related Genes Linked to Poor Outcome von Stavropoulou, Vaia, Kaspar, Susanne, Brault, Laurent, Sanders, Mathijs A., Juge, Sabine, Morettini, Stefano, Tzankov, Alexandar, Iacovino, Michelina, Lau, I-Jun, Milne, Thomas A., Royo, Hélène, Kyba, Michael, Valk, Peter J.M., Peters, Antoine H.F.M., Schwaller, Juerg

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Mesenchymal Inflammation Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Disease Evolution in Human Pre-leukemia von Zambetti, Noemi A., Ping, Zhen, Chen, Si, Kenswil, Keane J.G., Mylona, Maria A., Sanders, Mathijs A., Hoogenboezem, Remco M., Bindels, Eric M.J., Adisty, Maria N., Van Strien, Paulina M.H., van der Leije, Cindy S., Westers, Theresia M., Cremers, Eline M.P., Milanese, Chiara, Mastroberardino, Pier G., van Leeuwen, Johannes P.T.M., van der Eerden, Bram C.J., Touw, Ivo P., Kuijpers, Taco W., Kanaar, Roland, van de Loosdrecht, Arjan A., Vogl, Thomas, Raaijmakers, Marc H.G.P.

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A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia von Gröschel, Stefan, Sanders, Mathijs A, Hoogenboezem, Remco, de Wit, Elzo, Bouwman, Britta A M, Erpelinck, Claudia, van der Velden, Vincent H J, Havermans, Marije, Avellino, Roberto, van Lom, Kirsten, Rombouts, Elwin J, van Duin, Mark, Döhner, Konstanze, Beverloo, H Berna, Bradner, James E, Döhner, Hartmut, Löwenberg, Bob, Valk, Peter J M, Bindels, Eric M J, de Laat, Wouter, Delwel, Ruud

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The landscape of somatic mutation in normal colorectal epithelial cells von Lee-Six, Henry, Olafsson, Sigurgeir, Ellis, Peter, Osborne, Robert J., Sanders, Mathijs A., Moore, Luiza, Georgakopoulos, Nikitas, Torrente, Franco, Noorani, Ayesha, Goddard, Martin, Robinson, Philip, Coorens, Tim H. H., O’Neill, Laura, Alder, Christopher, Wang, Jingwei, Fitzgerald, Rebecca C., Zilbauer, Matthias, Coleman, Nicholas, Saeb-Parsy, Kourosh, Martincorena, Inigo, Campbell, Peter J., Stratton, Michael R.

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Somatic mutations and clonal dynamics in healthy and cirrhotic human liver von Brunner, Simon F., Roberts, Nicola D., Wylie, Luke A., Moore, Luiza, Aitken, Sarah J., Davies, Susan E., Sanders, Mathijs A., Ellis, Pete, Alder, Chris, Hooks, Yvette, Abascal, Federico, Stratton, Michael R., Martincorena, Inigo, Hoare, Matthew, Campbell, Peter J.

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The mutational landscape of normal human endometrial epithelium von Moore, Luiza, Leongamornlert, Daniel, Coorens, Tim H. H., Sanders, Mathijs A., Ellis, Peter, Dentro, Stefan C., Dawson, Kevin J., Butler, Tim, Rahbari, Raheleh, Mitchell, Thomas J., Maura, Francesco, Nangalia, Jyoti, Tarpey, Patrick S., Brunner, Simon F., Lee-Six, Henry, Hooks, Yvette, Moody, Sarah, Mahbubani, Krishnaa T., Jimenez-Linan, Mercedes, Brosens, Jan J., Iacobuzio-Donahue, Christine A., Martincorena, Inigo, Saeb-Parsy, Kourosh, Campbell, Peter J., Stratton, Michael R.

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Lifting the veil on germline DDX41 mutations von Sanders, Mathijs A.

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Somatic Evolution in Non-neoplastic IBD-Affected Colon von Olafsson, Sigurgeir, McIntyre, Rebecca E., Coorens, Tim, Butler, Timothy, Jung, Hyunchul, Robinson, Philip S., Lee-Six, Henry, Sanders, Mathijs A., Arestang, Kenneth, Dawson, Claire, Tripathi, Monika, Strongili, Konstantina, Hooks, Yvette, Stratton, Michael R., Parkes, Miles, Martincorena, Inigo, Raine, Tim, Campbell, Peter J., Anderson, Carl A.

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Convergent somatic mutations in metabolism genes in chronic liver disease von Ng, Stanley W. K., Rouhani, Foad J., Brunner, Simon F., Brzozowska, Natalia, Aitken, Sarah J., Yang, Ming, Abascal, Federico, Moore, Luiza, Nikitopoulou, Efterpi, Chappell, Lia, Leongamornlert, Daniel, Ivovic, Aleksandra, Robinson, Philip, Butler, Timothy, Sanders, Mathijs A., Williams, Nicholas, Coorens, Tim H. H., Teague, Jon, Raine, Keiran, Butler, Adam P., Hooks, Yvette, Wilson, Beverley, Birtchnell, Natalie, Naylor, Huw, Davies, Susan E., Stratton, Michael R., Martincorena, Iñigo, Rahbari, Raheleh, Frezza, Christian, Hoare, Matthew, Campbell, Peter J.

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Integrative genomic and transcriptomic analysis of leiomyosarcoma von Chudasama, Priya, Mughal, Sadaf S., Sanders, Mathijs A., Hübschmann, Daniel, Chung, Inn, Deeg, Katharina I., Wong, Siao-Han, Rabe, Sophie, Hlevnjak, Mario, Zapatka, Marc, Ernst, Aurélie, Kleinheinz, Kortine, Schlesner, Matthias, Sieverling, Lina, Klink, Barbara, Schröck, Evelin, Hoogenboezem, Remco M., Kasper, Bernd, Heilig, Christoph E., Egerer, Gerlinde, Wolf, Stephan, von Kalle, Christof, Eils, Roland, Stenzinger, Albrecht, Weichert, Wilko, Glimm, Hanno, Gröschel, Stefan, Kopp, Hans-Georg, Omlor, Georg, Lehner, Burkhard, Bauer, Sebastian, Schimmack, Simon, Ulrich, Alexis, Mechtersheimer, Gunhild, Rippe, Karsten, Brors, Benedikt, Hutter, Barbara, Renner, Marcus, Hohenberger, Peter, Scholl, Claudia, Fröhling, Stefan

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Increased somatic mutation burdens in normal human cells due to defective DNA polymerases von Robinson, Philip S., Coorens, Tim H. H., Palles, Claire, Mitchell, Emily, Abascal, Federico, Olafsson, Sigurgeir, Lee, Bernard C. H., Lawson, Andrew R. J., Lee-Six, Henry, Moore, Luiza, Sanders, Mathijs A., Hewinson, James, Martin, Lynn, Pinna, Claudia M. A., Galavotti, Sara, Rahbari, Raheleh, Campbell, Peter J., Martincorena, Iñigo, Tomlinson, Ian, Stratton, Michael R.

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Prognostic Value of FLT3 -Internal Tandem Duplication Residual Disease in Acute Myeloid Leukemia von Grob, Tim, Sanders, Mathijs A, Vonk, Christian M, Kavelaars, Franҫois G, Rijken, Melissa, Hanekamp, Diana W, Gradowska, Patrycja L, Cloos, Jacqueline, Fløisand, Yngvar, van Marwijk Kooy, Marinus, Manz, Markus G, Ossenkoppele, Gert J, Tick, Lidwine W, Havelange, Violaine, Löwenberg, Bob, Jongen-Lavrencic, Mojca, Valk, Peter J M

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Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia von Li, Sheng, Garrett-Bakelman, Francine E, Chung, Stephen S, Sanders, Mathijs A, Hricik, Todd, Rapaport, Franck, Patel, Jay, Dillon, Richard, Vijay, Priyanka, Brown, Anna L, Perl, Alexander E, Cannon, Joy, Bullinger, Lars, Luger, Selina, Becker, Michael, Lewis, Ian D, To, Luen Bik, Delwel, Ruud, Löwenberg, Bob, Döhner, Hartmut, Döhner, Konstanze, Guzman, Monica L, Hassane, Duane C, Roboz, Gail J, Grimwade, David, Valk, Peter J M, D'Andrea, Richard J, Carroll, Martin, Park, Christopher Y, Neuberg, Donna, Levine, Ross, Melnick, Ari M, Mason, Christopher E

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Somatic mutation rates scale with lifespan across mammals von Cagan, Alex, Baez-Ortega, Adrian, Brzozowska, Natalia, Abascal, Federico, Coorens, Tim H. H., Sanders, Mathijs A., Lawson, Andrew R. J., Harvey, Luke M. R., Bhosle, Shriram, Jones, David, Alcantara, Raul E., Butler, Timothy M., Hooks, Yvette, Roberts, Kirsty, Anderson, Elizabeth, Lunn, Sharna, Flach, Edmund, Spiro, Simon, Januszczak, Inez, Wrigglesworth, Ethan, Jenkins, Hannah, Dallas, Tilly, Masters, Nic, Perkins, Matthew W., Deaville, Robert, Druce, Megan, Bogeska, Ruzhica, Milsom, Michael D., Neumann, Björn, Gorman, Frank, Constantino-Casas, Fernando, Peachey, Laura, Bochynska, Diana, Smith, Ewan St. John, Gerstung, Moritz, Campbell, Peter J., Murchison, Elizabeth P., Stratton, Michael R., Martincorena, Iñigo

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The mutational landscape of human somatic and germline cells von Moore, Luiza, Cagan, Alex, Coorens, Tim H. H., Neville, Matthew D. C., Sanghvi, Rashesh, Sanders, Mathijs A., Oliver, Thomas R. W., Leongamornlert, Daniel, Ellis, Peter, Noorani, Ayesha, Mitchell, Thomas J., Butler, Timothy M., Hooks, Yvette, Warren, Anne Y., Jorgensen, Mette, Dawson, Kevin J., Menzies, Andrew, O’Neill, Laura, Latimer, Calli, Teng, Mabel, van Boxtel, Ruben, Iacobuzio-Donahue, Christine A., Martincorena, Inigo, Heer, Rakesh, Campbell, Peter J., Fitzgerald, Rebecca C., Stratton, Michael R., Rahbari, Raheleh

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Extensive heterogeneity in somatic mutation and selection in the human bladder von Lawson, Andrew R J, Abascal, Federico, Coorens, Tim H H, Hooks, Yvette, O'Neill, Laura, Latimer, Calli, Raine, Keiran, Sanders, Mathijs A, Warren, Anne Y, Mahbubani, Krishnaa T A, Bareham, Bethany, Butler, Timothy M, Harvey, Luke M R, Cagan, Alex, Menzies, Andrew, Moore, Luiza, Colquhoun, Alexandra J, Turner, William, Thomas, Benjamin, Gnanapragasam, Vincent, Williams, Nicholas, Rassl, Doris M, Vöhringer, Harald, Zumalave, Sonia, Nangalia, Jyoti, Tubío, José M C, Gerstung, Moritz, Saeb-Parsy, Kourosh, Stratton, Michael R, Campbell, Peter J, Mitchell, Thomas J, Martincorena, Iñigo

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The multiple myeloma microenvironment is defined by an inflammatory stromal cell landscape von de Jong, Madelon M. E., Kellermayer, Zoltán, Papazian, Natalie, Tahri, Sabrin, Hofste op Bruinink, Davine, Hoogenboezem, Remco, Sanders, Mathijs A., van de Woestijne, Pieter C., Bos, P. Koen, Khandanpour, Cyrus, Vermeulen, Jessica, Moreau, Philippe, van Duin, Mark, Broijl, Annemiek, Sonneveld, Pieter, Cupedo, Tom

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Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing von Ellis, Peter, Moore, Luiza, Sanders, Mathijs A., Butler, Timothy M., Brunner, Simon F., Lee-Six, Henry, Osborne, Robert, Farr, Ben, Coorens, Tim H. H., Lawson, Andrew R. J., Cagan, Alex, Stratton, Mike R., Martincorena, Inigo, Campbell, Peter J.

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Madelon de Keizer, Als een meeuw op de golven. Albert Verwey en zijn tijd von Sanders, Mathijs

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