Thrombospondin-I is a critical modulator in non-alcoholic steatohepatitis (NASH) von Min-DeBartolo, Jessica, Schlerman, Franklin, Akare, Sandeep, Wang, Ju, McMahon, James, Zhan, Yutian, Syed, Jameel, He, Wen, Zhang, Baohong, Martinez, Robert V

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Docosahexaenoic acid supplementation fully restores fertility and spermatogenesis in male delta-6 desaturase-null mice von Roqueta-Rivera, Manuel, Stroud, Chad K., Haschek, Wanda M., Akare, Sandeep J., Segre, Mariangela, Brush, Richard S., Agbaga, Martin-Paul, Anderson, Robert E., Hess, Rex A., Nakamura, Manabu T.

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Apratoxin A Shows Novel Pancreas-Targeting Activity through the Binding of Sec 61 von Huang, Kuan-Chun, Chen, Zhihong, Jiang, Yimin, Akare, Sandeep, Kolber-Simonds, Donna, Condon, Krista, Agoulnik, Sergei, Tendyke, Karen, Shen, Yongchun, Wu, Kuo-Ming, Mathieu, Steven, Choi, Hyeong-Wook, Zhu, Xiaojie, Shimizu, Hajime, Kotake, Yoshihiko, Gerwick, William H, Uenaka, Toshimitsu, Woodall-Jappe, Mary, Nomoto, Kenichi

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Deoxycholic Acid Induces Intracellular Signaling through Membrane Perturbations von Jean-Louis, Samira, Akare, Sandeep, Ali, M. Ahad, Mash, Eugene A., Meuillet, Emmanuelle, Martinez, Jesse D.

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Brunner’s Gland Lesions in Rats Induced by a Vascular Endothelial Growth Factor Receptor Inhibitor von Inomata, Akira, Nakano-Ito, Kyoko, Fujikawa, Yasuhiro, Sonoda, Jiro, Hayakawa, Kazuhiro, Ohta, Etsuko, Taketa, Yoshikazu, Van Gessel, Yvonne, Akare, Sandeep, Hutto, David, Hosokawa, Satoru, Tsukidate, Kazuo

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Ursodeoxycholic acid modulates histone acetylation and induces differentiation and senescence von Akare, Sandeep, Jean‐Louis, Samira, Chen, Wemin, Wood, Daniel J., Powell, Ashley A., Martinez, Jesse D.

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Resistance to ursodeoxycholic acid-induced growth arrest can also result in resistance to deoxycholic acid-induced apoptosis and increased tumorgenicity von Powell, Ashley A, Akare, Sandeep, Qi, Wenqing, Herzer, Pascal, Jean-Louis, Samira, Feldman, Rebecca A, Martinez, Jesse D

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Apratoxin‐A Induces Pancreatic Toxicity von Akare, Sandeep, Condon, Krista, Eckley, Sean, Huang, Kuan‐Chun, Chen, Zhihong, Jiang, Yimin, Kotake, Yoshihiko, Van Gessel, Yvonne, Hutto, David

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Abstract 3126: H3B6527, a selective and potent FGFR4 inhibitor for FGF19-driven hepatocellular carcinoma von Selvaraj, Anand, Corcoran, Erik, Coffey, Heather, Prajapati, Sudeep, Hao, Ming-Hong, Larsen, Nicholas, Tsai, Jennifer, Satoh, Takashi, Ichikawa, Kana, Joshi, Julie Jaya, Hurley, Raelene, Wu, Jeremy, Huang, Chia-Ling, Bailey, Suzanna, Karr, Craig, Kumar, Pavan, Rimkunas, Victoria, Mackenzie, Crystal, Rioux, Nathalie, Kim, Amy, Akare, Sandeep, Lai, George, Yu, Lihua, Fekkes, Peter, Wang, John, Warmuth, Markus, Smith, Peter, Reynolds, Dominic

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Bile acid induces hydrophobicity-dependent membrane alterations von Akare, Sandeep, Martinez, Jesse D.

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Assessment of the translational value of mouse lupus models using clinically relevant biomarkers von Bender, Andrew T, Wu, Yin, Cao, Qiongfang, Ding, Yueyun, Oestreicher, Judith, Genest, Melinda, Akare, Sandeep, Ishizaka, Sally T, Mackey, Matthew F

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Evaluation of a candidate anti-arthritic drug using the mouse collagen antibody induced arthritis model and clinically relevant biomarkers von Bender, Andrew T, Spyvee, Mark, Satoh, Takashi, Gershman, Benjamin, Teceno, Tyler, Burgess, Laurette, Kumar, Vipul, Wu, Yin, Yang, Hua, Ding, Yueyun, Akare, Sandeep, Chen, Qian

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P-087 Brunner's Gland Lesions in Rats Induced by A Vascular Endothelial Growth Factor Receptor Inhibitor von Akira Inomata, Kyoko Nakano, Yasuhiro Fujikawa, Jiro Sonoda, Kazuhiro Hayakawa, Etsuko Ota, Yoshikazu Taketa, Yuki Seki, Aya Goto, Yvonne Van Gessel, Sandeep Akare, David Hutto, Satoru Hosokawa, Kazuo Tsukidate

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Parental HCT116 cells and HOMUR 7, 11, and 17 cells were plated at a density of 100,000 cells per 35 mm plate and incubated at 37°C for 48 hours von Powell, Ashley A, Akare, Sandeep, Wenqing Qi, Herzer, Pascal, Jean-Louis, Samira, Feldman, Rebecca A, Martinez, Jesse D

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HCT116, Homur7, Homur11, and Homur17 cells were plated into six well trays in 0 von Powell, Ashley A, Akare, Sandeep, Wenqing Qi, Herzer, Pascal, Jean-Louis, Samira, Feldman, Rebecca A, Martinez, Jesse D

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(A) HOMUR cells were incubated with 500 micromolar DCA for 24 hours and the fraction of apoptotic cells determined as described in Methods von Powell, Ashley A, Akare, Sandeep, Wenqing Qi, Herzer, Pascal, Jean-Louis, Samira, Feldman, Rebecca A, Martinez, Jesse D

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