279 Preclinical evaluation of allogeneic CD19 CAR T cells expressing an anti-rejection CD70 CAR von Lauron, Elvin J, Zhang, Kristen, Sanchez, Jerick, Ramanathan, Vidhya, Nguyen, Duy, Nguyen, George, Sasu, Barbra, Sommer, Cesar

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Tumors establish resistance to immunotherapy by regulating Treg recruitment via CCR4 von Marshall, Lisa A, Marubayashi, Sachie, Jorapur, Aparna, Jacobson, Scott, Zibinsky, Mikhail, Robles, Omar, Hu, Dennis Xiaozhou, Jackson, Jeffrey J, Pookot, Deepa, Sanchez, Jerick, Brovarney, Martin, Wadsworth, Angela, Chian, David, Wustrow, David, Kassner, Paul D, Cutler, Gene, Wong, Brian, Brockstedt, Dirk G, Talay, Oezcan

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Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity von Leger, Paul R, Hu, Dennis X, Biannic, Berenger, Bui, Minna, Han, Xinping, Karbarz, Emily, Maung, Jack, Okano, Akinori, Osipov, Maksim, Shibuya, Grant M, Young, Kyle, Higgs, Christopher, Abraham, Betty, Bradford, Delia, Cho, Cynthia, Colas, Christophe, Jacobson, Scott, Ohol, Yamini M, Pookot, Deepa, Rana, Payal, Sanchez, Jerick, Shah, Niket, Sun, Michael, Wong, Steve, Brockstedt, Dirk G, Kassner, Paul D, Schwarz, Jacob B, Wustrow, David J

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Tumors establish resistance to immunotherapy by regulating T reg recruitment via CCR4 von Marshall, Lisa A, Marubayashi, Sachie, Jorapur, Aparna, Jacobson, Scott, Zibinsky, Mikhail, Robles, Omar, Hu, Dennis Xiaozhou, Jackson, Jeffrey J, Pookot, Deepa, Sanchez, Jerick, Brovarney, Martin, Wadsworth, Angela, Chian, David, Wustrow, David, Kassner, Paul D, Cutler, Gene, Wong, Brian, Brockstedt, Dirk G, Talay, Oezcan

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Novel, Selective Inhibitors of USP7 Uncover Multiple Mechanisms of Antitumor Activity In Vitro and In Vivo von Ohol, Yamini M., Sun, Michael T., Cutler, Gene, Leger, Paul R., Hu, Dennis X., Biannic, Berenger, Rana, Payal, Cho, Cynthia, Jacobson, Scott, Wong, Steve T., Sanchez, Jerick, Shah, Niket, Pookot, Deepa, Abraham, Betty, Young, Kyle, Suthram, Silpa, Marshall, Lisa A., Bradford, Delia, Kozon, Nathan, Han, Xinping, Okano, Akinori, Maung, Jack, Colas, Christophe, Schwarz, Jacob, Wustrow, David, Brockstedt, Dirk G., Kassner, Paul D.

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Abstract 1646: Development of small-molecule HPK1 inhibitors to unleash tumor-specific T cell responses von Katibah, George, Ohol, Yamini, Bucher, Cyril, Adusumilli, Lavanya, Kaveri, Deepika, Robles, Omar, Sun, Michael, Cho, Cynthia, Milestone, Heather, Ames, Rachel, Jacobson, Scott, Nebalasca, Dan, Gomez- Guagua, Justy, Sanchez, Jerick, Grandcolas, Molly, Wong, Steve, Brovarney, Martin, Ramana, Chandru, Zaw, Thant, Nguyen, Lan, Tivitmahaisoon, Parcharee, Ng, Andrew, Ma, Anqi, Gomez, Blanca, Ko, Michelle, Leger, Paul, Jackson, Jeffrey, Shibuya, Grant, Shakhmin, Anton, Bradford, Delia, Xu, Mengshu, Zibinsky, Mikhail, Poon, Daniel, Wustrow, David, Kassner, Paul, Brockstedt, Dirk

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Abstract 1104: Targeting the stress response kinase GCN2 to restore immunity in the tumor microenvironment von Ravishankar, Buvana, Adusumilli, Lavanya, Pookot, Deepa Pookot, Huang, Emily, Sreenivasan, Raashi, Marshall, Lisa, Kaveri, Deepika, Talay, Oezcan, Suthram, Silpa, Miakicheva, Svetlana, Okal, Abood, Zibinsky, Mikhail, Jackson, Jeffrey, Shibuya, Grant, Leger, Paul, Tivitmahaisoon, Parcharee, Jacobson, Scott, Wong, Steve, Wadsworth, Angela, Sanchez, Jerick, Brovarney, Martin, Chian, David, Marubayashi, Sachie, Jorapur, Aparna, Bradford, Delia, Colas, Christophe, Cutler, Gene, Schwartz, Jacob, Wustrow, David, Kassner, Paul, Brockstedt, Dirk

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Abstract 4441: Discovery of potent and selective inhibitors of USP7 with anti-tumor activity in vitro and in vivo von Ohol, Yamini M., Sun, Michael, Leger, Paul, Hu, Dennis, Biannic, Berenger, Rana, Payal, Cho, Cynthia, Jacobson, Scott, Wong, Steve, Sanchez, Jerick, Han, Xinping, Young, Kyle, Okano, Akinori, Maung, Jack, Cutler, Gene, Shah, Nick, Adusumilli, Lavanya, Kaveri, Deepika, Talay, Oezcan, Pookot, Deepa, Abraham, Betty, Bradford, Delia, Kozon, Nathan, Colas, Christophe, Kim, Andrea, Schwarz, Jacob, Wustrow, David, Brockstedt, Dirk, Kassner, Paul

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FLX193: A Potent, Selective CCR4 Antagonist for Allergic Disorders von Jorapur, Aparna, Marshall, Lisa, Bradford, Delia, Brovarney, Martin, Chian, David, Wadsworth, Angela, Sanchez, Jerick, Jacobson, Scott, Karbarz, Emily, Robles, Omar, Younai, Ashkaan, Ketcham, John, Ng, Andrew, Tivitmahaisoon, Parcharee, Pookot, Deepa, Marubayashi, Sachie, Kozon, Nathan, Colas, Christophe, Okal, Abood, Cutler, Gene, Wustrow, David, Schwarz, Jacob, Talay, Oezcan, Brockstedt, Dirk, Wong, Brian

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