Genomic Landscape of Atypical Adenomatous Hyperplasia Reveals Divergent Modes to Lung Adenocarcinoma von Sivakumar, Smruthy, Lucas, F Anthony San, McDowell, Tina L, Lang, Wenhua, Xu, Li, Fujimoto, Junya, Zhang, Jianjun, Futreal, P Andrew, Fukuoka, Junya, Yatabe, Yasushi, Dubinett, Steven M, Spira, Avrum E, Fowler, Jerry, Hawk, Ernest T, Wistuba, Ignacio I, Scheet, Paul, Kadara, Humam

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Single-Cell Transcriptomics of Pancreatic Cancer Precursors Demonstrates Epithelial and Microenvironmental Heterogeneity as an Early Event in Neoplastic Progression von Bernard, Vincent, Semaan, Alexander, Huang, Jonathan, San Lucas, F Anthony, Mulu, Feven C, Stephens, Bret M, Guerrero, Paola A, Huang, Yanqing, Zhao, Jun, Kamyabi, Nabiollah, Sen, Subrata, Scheet, Paul A, Taniguchi, Cullen M, Kim, Michael P, Tzeng, Ching-Wei, Katz, Matthew H, Singhi, Aatur D, Maitra, Anirban, Alvarez, Hector A

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Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism von Zhao, Hongyun, Yang, Lifeng, Baddour, Joelle, Achreja, Abhinav, Bernard, Vincent, Moss, Tyler, Marini, Juan C, Tudawe, Thavisha, Seviour, Elena G, San Lucas, F Anthony, Alvarez, Hector, Gupta, Sonal, Maiti, Sourindra N, Cooper, Laurence, Peehl, Donna, Ram, Prahlad T, Maitra, Anirban, Nagrath, Deepak

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Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes von Riquelme, Erick, Zhang, Yu, Zhang, Liangliang, Montiel, Maria, Zoltan, Michelle, Dong, Wenli, Quesada, Pompeyo, Sahin, Ismet, Chandra, Vidhi, San Lucas, Anthony, Scheet, Paul, Xu, Hanwen, Hanash, Samir M., Feng, Lei, Burks, Jared K., Do, Kim-Anh, Peterson, Christine B., Nejman, Deborah, Tzeng, Ching-Wei D., Kim, Michael P., Sears, Cynthia L., Ajami, Nadim, Petrosino, Joseph, Wood, Laura D., Maitra, Anirban, Straussman, Ravid, Katz, Matthew, White, James Robert, Jenq, Robert, Wargo, Jennifer, McAllister, Florencia

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A Visually Apparent and Quantifiable CT Imaging Feature Identifies Biophysical Subtypes of Pancreatic Ductal Adenocarcinoma von Koay, Eugene J, Lee, Yeonju, Cristini, Vittorio, Lowengrub, John S, Kang, Ya'an, Lucas, F Anthony San, Hobbs, Brian P, Ye, Rong, Elganainy, Dalia, Almahariq, Muayad, Amer, Ahmed M, Chatterjee, Deyali, Yan, Huaming, Park, Peter C, Rios Perez, Mayrim V, Li, Dali, Garg, Naveen, Reiss, Kim A, Yu, Shun, Chauhan, Anil, Zaid, Mohamed, Nikzad, Newsha, Wolff, Robert A, Javle, Milind, Varadhachary, Gauri R, Shroff, Rachna T, Das, Prajnan, Lee, Jeffrey E, Ferrari, Mauro, Maitra, Anirban, Taniguchi, Cullen M, Kim, Michael P, Crane, Christopher H, Katz, Matthew H, Wang, Huamin, Bhosale, Priya, Tamm, Eric P, Fleming, Jason B

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DNA Sequencing of Small Bowel Adenocarcinomas Identifies Targetable Recurrent Mutations in the ERBB2 Signaling Pathway von Adam, Liana, San Lucas, F Anthony, Fowler, Richard, Yu, Yao, Wu, Wenhui, Liu, Yulun, Wang, Huamin, Menter, David, Tetzlaff, Michael T, Ensor, Jr, Joe, Manyam, Ganiraju, Arold, Stefan T, Huff, Chad, Kopetz, Scott, Scheet, Paul, Overman, Michael J

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Strategies for identification of somatic variants using the Ion Torrent deep targeted sequencing platform von Deshpande, Aditya, Lang, Wenhua, McDowell, Tina, Sivakumar, Smruthy, Zhang, Jiexin, Wang, Jing, San Lucas, F Anthony, Fowler, Jerry, Kadara, Humam, Scheet, Paul

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Genetic risk factors for the development of osteonecrosis in children under age 10 treated for acute lymphoblastic leukemia von Karol, Seth E., Mattano, Leonard A., Yang, Wenjian, Maloney, Kelly W., Smith, Colton, Liu, ChengCheng, Ramsey, Laura B., Fernandez, Christian A., Chang, Tamara Y., Neale, Geoffrey, Cheng, Cheng, Mardis, Elaine, Fulton, Robert, Scheet, Paul, San Lucas, F. Anthony, Larsen, Eric C., Loh, Mignon L., Raetz, Elizabeth A., Hunger, Stephen P., Devidas, Meenakshi, Relling, Mary V.

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Genomic Landscape of Colorectal Mucosa and Adenomas von Borras, Ester, San Lucas, F Anthony, Chang, Kyle, Zhou, Ruoji, Masand, Gita, Fowler, Jerry, Mork, Maureen E, You, Y Nancy, Taggart, Melissa W, McAllister, Florencia, Jones, David A, Davies, Gareth E, Edelmann, Winfried, Ehli, Erik A, Lynch, Patrick M, Hawk, Ernest T, Capella, Gabriel, Scheet, Paul, Vilar, Eduardo

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Mutational Heterogeneity in APC and KRAS Arises at the Crypt Level and Leads to Polyclonality in Early Colorectal Tumorigenesis von Gausachs, Mireia, Borras, Ester, Chang, Kyle, Gonzalez, Sara, Azuara, Daniel, Delgado Amador, Axel, Lopez-Doriga, Adriana, San Lucas, F Anthony, Sanjuan, Xavier, Paules, Maria J, Taggart, Melissa W, Davies, Gareth E, Ehli, Erik A, Fowler, Jerry, Moreno, Victor, Pineda, Marta, You, Y Nancy, Lynch, Patrick M, Lazaro, Conxi, Navin, Nicholas E, Scheet, Paul A, Hawk, Ernest T, Capella, Gabriel, Vilar, Eduardo

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Incorporating prior knowledge into Gene Network Study von Wang, Zixing, Xu, Wenlong, San Lucas, F Anthony, Liu, Yin

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Mitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer von Yu, Meifang, Nguyen, Nicholas D, Huang, Yanqing, Lin, Daniel, Fujimoto, Tara N, Molkentine, Jessica M, Deorukhkar, Amit, Kang, Ya'an, San Lucas, F Anthony, Fernandes, Conrad J, Koay, Eugene J, Gupta, Sonal, Ying, Haoqiang, Koong, Albert C, Herman, Joseph M, Fleming, Jason B, Maitra, Anirban, Taniguchi, Cullen M

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Driver Mutations in Normal Airway Epithelium Elucidate Spatiotemporal Resolution of Lung Cancer von Kadara, Humam, Sivakumar, Smruthy, Jakubek, Yasminka, San Lucas, F Anthony, Lang, Wenhua, McDowell, Tina, Weber, Zachary, Behrens, Carmen, Davies, Gareth E, Kalhor, Neda, Moran, Cesar, El-Zein, Randa, Mehran, Reza, Swisher, Stephen G, Wang, Jing, Zhang, Jianjun, Fujimoto, Junya, Fowler, Jerry, Heymach, John V, Dubinett, Steven, Spira, Avrum E, Ehli, Erik A, Wistuba, Ignacio I, Scheet, Paul

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Identifying microRNA targets in different gene regions von Xu, Wenlong, San Lucas, Anthony, Wang, Zixing, Liu, Yin

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Pan cancer patterns of allelic imbalance from chromosomal alterations in 33 tumor types von Sivakumar, Smruthy, San Lucas, F Anthony, Jakubek, Yasminka A, Ozcan, Zuhal, Fowler, Jerry, Scheet, Paul

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Rapid and powerful detection of subtle allelic imbalance from exome sequencing data with hapLOHseq von San Lucas, F Anthony, Sivakumar, Smruthy, Vattathil, Selina, Fowler, Jerry, Vilar, Eduardo, Scheet, Paul

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Preliminary whole-exome sequencing reveals mutations that imply common tumorigenicity pathways in multiple endocrine neoplasia type 1 patients von Romero Arenas, Minerva Angélica, MD, MPH, Fowler, Richard G., PhD, San Lucas, F. Anthony, MS, Shen, Jie, PhD, Rich, Thereasa A., MS, Grubbs, Elizabeth G., MD, Lee, Jeffrey E., MD, Scheet, Paul, PhD, Perrier, Nancy D., MD, Zhao, Hua, PhD

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Improving the sensitivity of sample clustering by leveraging gene co-expression networks in variable selection von Wang, Zixing, San Lucas, F Anthony, Qiu, Peng, Liu, Yin

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Assessing inter-component heterogeneity of biphasic uterine carcinosarcomas von Liu, Yihua, Weber, Zachary, San Lucas, F. Anthony, Deshpande, Aditya, Jakubek, Yasminka A., Sulaiman, Raed, Fagerness, Mary, Flier, Natasha, Sulaiman, Joseph, Davis, Christel M., Fowler, Jerry, Starks, David, Rojas-Espaillat, Luis, Lazar, Alexander J., Davies, Gareth E., Ehli, Erik A., Scheet, Paul

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HIF2 Regulates Intestinal Wnt5a Expression von Garcia Garcia, Carolina J., Acevedo Diaz, Ariana C., Kumari, Neeraj, Govindaraju, Suman, de la Cruz Bonilla, Marimar, San Lucas, F. Anthony, Nguyen, Nicholas D., Jimenez Sacarello, Iancarlos, Piwnica-Worms, Helen, Maitra, Anirban, Taniguchi, Cullen M.

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