The JAK-STAT pathway regulates CD38 on myeloma cells in the bone marrow microenvironment: therapeutic implications von Ogiya, Daisuke, Liu, Jiye, Ohguchi, Hiroto, Kurata, Keiji, Samur, Mehmet K., Tai, Yu-Tzu, Adamia, Sophia, Ando, Kiyoshi, Hideshima, Teru, Anderson, Kenneth C.

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Lenalidomide Enhances Immune Checkpoint Blockade-Induced Immune Response in Multiple Myeloma von Görgün, Güllü, Samur, Mehmet K, Cowens, Kristen B, Paula, Steven, Bianchi, Giada, Anderson, Julie E, White, Randie E, Singh, Ahaana, Ohguchi, Hiroto, Suzuki, Rikio, Kikuchi, Shohei, Harada, Takeshi, Hideshima, Teru, Tai, Yu-Tzu, Laubach, Jacob P, Raje, Noopur, Magrangeas, Florence, Minvielle, Stephane, Avet-Loiseau, Herve, Munshi, Nikhil C, Dorfman, David M, Richardson, Paul G, Anderson, Kenneth C

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Widespread intronic polyadenylation diversifies immune cell transcriptomes von Singh, Irtisha, Lee, Shih-Han, Sperling, Adam S., Samur, Mehmet K., Tai, Yu-Tzu, Fulciniti, Mariateresa, Munshi, Nikhil C., Mayr, Christine, Leslie, Christina S.

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MUC1-C Activates the NuRD Complex to Drive Dedifferentiation of Triple-Negative Breast Cancer Cells von Hata, Tsuyoshi, Rajabi, Hasan, Takahashi, Hidekazu, Yasumizu, Yota, Li, Wei, Jin, Caining, Long, Mark D, Hu, Qiang, Liu, Song, Fushimi, Atsushi, Yamashita, Nami, Kui, Ling, Hong, Deli, Yamamoto, Masaaki, Miyo, Masaaki, Hiraki, Masayuki, Maeda, Takahiro, Suzuki, Yozo, Samur, Mehmet K, Kufe, Donald

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Bone marrow stromal cells induce chromatin remodeling in multiple myeloma cells leading to transcriptional changes von Binder, Moritz, Szalat, Raphael E., Talluri, Srikanth, Fulciniti, Mariateresa, Avet-Loiseau, Hervé, Parmigiani, Giovanni, Samur, Mehmet K., Munshi, Nikhil C.

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The KDM3A–KLF2–IRF4 axis maintains myeloma cell survival von Ohguchi, Hiroto, Hideshima, Teru, Bhasin, Manoj K., Gorgun, Gullu T., Santo, Loredana, Cea, Michele, Samur, Mehmet K., Mimura, Naoya, Suzuki, Rikio, Tai, Yu-Tzu, Carrasco, Ruben D., Raje, Noopur, Richardson, Paul G., Munshi, Nikhil C., Harigae, Hideo, Sanda, Takaomi, Sakai, Juro, Anderson, Kenneth C.

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Dysregulated APOBEC3G causes DNA damage and promotes genomic instability in multiple myeloma von Talluri, Srikanth, Samur, Mehmet K., Buon, Leutz, Kumar, Subodh, Potluri, Lakshmi B., Shi, Jialan, Prabhala, Rao H., Shammas, Masood A., Munshi, Nikhil C.

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Apoptosis reprogramming triggered by splicing inhibitors sensitizes multiple myeloma cells to Venetoclax treatment von Soncini, Debora, Martinuzzi, Claudia, Becherini, Pamela, Gelli, Elisa, Ruberti, Samantha, Todoerti, Katia, Mastracci, Luca, Contini, Paola, Cagnetta, Antonia, Laudisi, Antonella, Guolo, Fabio, Minetto, Paola, Miglino, Maurizio, Aquino, Sara, Varaldo, Riccardo, Reverberi, Daniele, Formica, Matteo, Passalacqua, Mario, Nencioni, Alessio, Neri, Antonino, Samur, Mehmet K, Munshi, Nikhil C, Fulciniti, Mariateresa, Lemoli, Roberto M, Cea, Michele

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p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma von Hideshima, Teru, Cottini, Francesca, Nozawa, Yoshihisa, Seo, Hyuk-Soo, Ohguchi, Hiroto, Samur, Mehmet K., Cirstea, Diana, Mimura, Naoya, Iwasawa, Yoshikazu, Richardson, Paul G., Munshi, Nikhil C., Chauhan, Dharminder, Massefski, Walter, Utsugi, Teruhiro, Dhe-Paganon, Sirano, Anderson, Kenneth C.

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In-depth analysis of alternative splicing landscape in multiple myeloma and potential role of dysregulated splicing factors von Aktas Samur, Anil, Fulciniti, Mariateresa, Avet-Loiseau, Herve, Lopez, Michael A., Derebail, Sanika, Corre, Jill, Minvielle, Stephane, Magrangeas, Florence, Moreau, Philippe, Anderson, Kenneth C., Parmigiani, Giovanni, Samur, Mehmet K., Munshi, Nikhil C.

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Ribonucleotide Reductase Catalytic Subunit M1 (RRM1) as a Novel Therapeutic Target in Multiple Myeloma von Sagawa, Morihiko, Ohguchi, Hiroto, Harada, Takeshi, Samur, Mehmet K, Tai, Yu-Tzu, Munshi, Nikhil C, Kizaki, Masahiro, Hideshima, Teru, Anderson, Kenneth C

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Stromal CCR6 drives tumor growth in a murine transplantable colon cancer through recruitment of tumor-promoting macrophages von Nandi, Bisweswar, Shapiro, Mia, Samur, Mehmet K., Pai, Christine, Frank, Natasha Y., Yoon, Charles, Prabhala, Rao H., Munshi, Nikhil C., Gold, Jason S.

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Role of apurinic/apyrimidinic nucleases in the regulation of homologous recombination in myeloma: mechanisms and translational significance von Kumar, Subodh, Talluri, Srikanth, Pal, Jagannath, Yuan, Xiaoli, Lu, Renquan, Nanjappa, Puru, Samur, Mehmet K., Munshi, Nikhil C., Shammas, Masood A.

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Differential and limited expression of mutant alleles in multiple myeloma von Rashid, Naim U., Sperling, Adam S., Bolli, Niccolo, Wedge, David C., Van Loo, Peter, Tai, Yu-Tzu, Shammas, Masood A., Fulciniti, Mariateresa, Samur, Mehmet K., Richardson, Paul G., Magrangeas, Florence, Minvielle, Stephane, Futreal, P. Andrew, Anderson, Kenneth C., Avet-Loiseau, Herve, Campbell, Peter J., Parmigiani, Giovanni, Munshi, Nikhil C.

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Non-overlapping Control of Transcriptome by Promoter- and Super-Enhancer-Associated Dependencies in Multiple Myeloma von Fulciniti, Mariateresa, Lin, Charles Y., Samur, Mehmet K., Lopez, Michael A., Singh, Irtisha, Lawlor, Matthew A., Szalat, Raphael E., Ott, Christopher J., Avet-Loiseau, Herve’, Anderson, Kenneth C., Young, Richard A., Bradner, James E., Munshi, Nikhil C.

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Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma von Kurata, Keiji, James-Bott, Anna, Tye, Mark A., Yamamoto, Leona, Samur, Mehmet K., Tai, Yu-Tzu, Dunford, James, Johansson, Catrine, Senbabaoglu, Filiz, Philpott, Martin, Palmer, Charlotte, Ramasamy, Karthik, Gooding, Sarah, Smilova, Mihaela, Gaeta, Giorgia, Guo, Manman, Christianson, John C., Payne, N. Connor, Singh, Kritika, Karagoz, Kubra, Stokes, Matthew E., Ortiz, Maria, Hagner, Patrick, Thakurta, Anjan, Cribbs, Adam, Mazitschek, Ralph, Hideshima, Teru, Anderson, Kenneth C., Oppermann, Udo

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Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma von Ohguchi, Hiroto, Park, Paul M C, Wang, Tingjian, Gryder, Berkley E, Ogiya, Daisuke, Kurata, Keiji, Zhang, Xiaofeng, Li, Deyao, Pei, Chengkui, Masuda, Takeshi, Johansson, Catrine, Wimalasena, Virangika K, Kim, Yong, Hino, Shinjiro, Usuki, Shingo, Kawano, Yawara, Samur, Mehmet K, Tai, Yu-Tzu, Munshi, Nikhil C, Matsuoka, Masao, Ohtsuki, Sumio, Nakao, Mitsuyoshi, Minami, Takashi, Lauberth, Shannon, Khan, Javed, Oppermann, Udo, Durbin, Adam D, Anderson, Kenneth C, Hideshima, Teru, Qi, Jun

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Correction: Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma von Kurata, Keiji, James-Bott, Anna, Tye, Mark A., Yamamoto, Leona, Samur, Mehmet K., Tai, Yu-Tzu, Dunford, James, Johansson, Catrine, Senbabaoglu, Filiz, Philpott, Martin, Palmer, Charlotte, Ramasamy, Karthik, Gooding, Sarah, Smilova, Mihaela, Gaeta, Giorgia, Guo, Manman, Christianson, John C., Payne, N. Connor, Singh, Kritika, Karagoz, Kubra, Stokes, Matthew E., Ortiz, Maria, Hagner, Patrick, Thakurta, Anjan, Cribbs, Adam, Mazitschek, Ralph, Hideshima, Teru, Anderson, Kenneth C., Oppermann, Udo

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Amplification and overexpression of E2 ubiquitin conjugase UBE2T promotes homologous recombination in multiple myeloma von Alagpulinsa, David A., Kumar, Subodh, Talluri, Srikanth, Nanjappa, Purushothama, Buon, Leutz, Chakraborty, Chandraditya, Samur, Mehmet K., Szalat, Raphael, Shammas, Masood A., Munshi, Nikhil C.

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BRD9 Degradation Disrupts Ribosome Biogenesis in Multiple Myeloma von Kurata, Keiji, Samur, Mehmet K, Liow, Priscilla, Wen, Kenneth, Yamamoto, Leona, Liu, Jiye, Morelli, Eugenio, Gulla, Annamaria, Tai, Yu-Tzu, Qi, Jun, Hideshima, Teru, Anderson, Kenneth C

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