Hyaluronic acid fuels pancreatic cancer cell growth von Kim, Peter K, Halbrook, Christopher J, Kerk, Samuel A, Radyk, Megan, Wisner, Stephanie, Kremer, Daniel M, Sajjakulnukit, Peter, Andren, Anthony, Hou, Sean W, Trivedi, Ayush, Thurston, Galloway, Anand, Abhinav, Yan, Liang, Salamanca-Cardona, Lucia, Welling, Samuel D, Zhang, Li, Pratt, Matthew R, Keshari, Kayvan R, Ying, Haoqiang, Lyssiotis, Costas A

Volltext

The human type 2 diabetes-specific visceral adipose tissue proteome and transcriptome in obesity von Carruthers, Nicholas J., Strieder-Barboza, Clarissa, Caruso, Joseph A., Flesher, Carmen G., Baker, Nicki A., Kerk, Samuel A., Ky, Alexander, Ehlers, Anne P., Varban, Oliver A., Lyssiotis, Costas A., Lumeng, Carey N., Stemmer, Paul M., O’Rourke, Robert W.

Volltext

Expansion of cat-ELCCA for the Discovery of Small Molecule Inhibitors of the Pre-let-7–Lin28 RNA–Protein Interaction von Lorenz, Daniel A, Kaur, Tanpreet, Kerk, Samuel A, Gallagher, Erin E, Sandoval, Jorge, Garner, Amanda L

Volltext

Metabolic networks in mutant KRAS-driven tumours: tissue specificities and the microenvironment von Kerk, Samuel A., Papagiannakopoulos, Thales, Shah, Yatrik M., Lyssiotis, Costas A.

Volltext

Protocol to generate human liver spheroids to study liver fibrosis induced by metabolic stress von Kim, Hyun Young, Lee, Wonseok, Liu, Xiao, Jang, Haeum, Sakane, Sadatsugu, Carvalho-Gontijo Weber, Raquel, Diggle, Karin, Kerk, Samuel A., Metallo, Christian M., Kisseleva, Tatiana, Brenner, David A.

Volltext

Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress von Devenport, Samantha N., Singhal, Rashi, Radyk, Megan D., Taranto, Joseph G., Kerk, Samuel A., Chen, Brandon, Goyert, Joshua W., Jain, Chesta, Das, Nupur K., Oravecz-Wilson, Katherine, Li Zhang, Greenson, Joel K., Chen, Y. Eugene, Soleimanpour, Scott A., Reddy, Pavan, Lyssiotis, Costas A., Shah, Yatrik M.

Volltext

HIF-2 alpha activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron von Singhal, Rashi, Mitta, Sreedhar R., Das, Nupur K., Kerk, Samuel A., Sajjakulnukit, Peter, Solanki, Sumeet, Andren, Anthony, Kumar, Roshan, Olive, Kenneth P., Banerjee, Ruma, Lyssiotis, Costas A., Shah, Yatrik M.

Volltext

Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance von Bell, Hannah N., Rebernick, Ryan J., Goyert, Joshua, Singhal, Rashi, Kuljanin, Miljan, Kerk, Samuel A., Huang, Wesley, Das, Nupur K., Andren, Anthony, Solanki, Sumeet, Miller, Shannon L., Todd, Peter K., Fearon, Eric R., Lyssiotis, Costas A., Gygi, Steven P., Mancias, Joseph D., Shah, Yatrik M.

Volltext

GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis von Kremer, Daniel M., Nelson, Barbara S., Lin, Lin, Yarosz, Emily L., Halbrook, Christopher J., Kerk, Samuel A., Sajjakulnukit, Peter, Myers, Amy, Thurston, Galloway, Hou, Sean W., Carpenter, Eileen S., Andren, Anthony C., Nwosu, Zeribe C., Cusmano, Nicholas, Wisner, Stephanie, Mbah, Nneka E., Shan, Mengrou, Das, Nupur K., Magnuson, Brian, Little, Andrew C., Savani, Milan R., Ramos, Johanna, Gao, Tina, Sastra, Stephen A., Palermo, Carmine F., Badgley, Michael A., Zhang, Li, Asara, John M., McBrayer, Samuel K., di Magliano, Marina Pasca, Crawford, Howard C., Shah, Yatrik M., Olive, Kenneth P., Lyssiotis, Costas A.

Volltext

Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer von Bell, Hannah N., Huber, Amanda K., Singhal, Rashi, Korimerla, Navyateja, Rebernick, Ryan J., Kumar, Roshan, El-derany, Marwa O., Sajjakulnukit, Peter, Das, Nupur K., Kerk, Samuel A., Solanki, Sumeet, James, Jadyn G., Kim, Donghwan, Zhang, Li, Chen, Brandon, Mehra, Rohit, Frankel, Timothy L., Győrffy, Balázs, Fearon, Eric R., Pasca di Magliano, Marina, Gonzalez, Frank J., Banerjee, Ruma, Wahl, Daniel R., Lyssiotis, Costas A., Green, Michael, Shah, Yatrik M.

Volltext

Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption von Zhu, Lingxin, Tang, Yi, Li, Xiao-Yan, Kerk, Samuel A, Lyssiotis, Costas A, Sun, Xiaoyue, Wang, Zijun, Cho, Jung-Sun, Ma, Jun, Weiss, Stephen J

Volltext

A Zeb1/MtCK1 metabolic axis controls osteoclast activation and skeletal remodeling von Zhu, Lingxin, Tang, Yi, Li, Xiao‐Yan, Kerk, Samuel A, Lyssiotis, Costas A, Feng, Wenqing, Sun, Xiaoyue, Hespe, Geoffrey E, Wang, Zijun, Stemmler, Marc P, Brabletz, Simone, Brabletz, Thomas, Keller, Evan T, Ma, Jun, Cho, Jung‐Sun, Yang, Jingwen, Weiss, Stephen J

Volltext

Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context von Kerk, Samuel A, Lin, Lin, Myers, Amy L, Sutton, Damien J, Andren, Anthony, Sajjakulnukit, Peter, Zhang, Li, Zhang, Yaqing, Jiménez, Jennifer A, Nelson, Barbara S, Chen, Brandon, Robinson, Anthony, Thurston, Galloway, Kemp, Samantha B, Steele, Nina G, Hoffman, Megan T, Wen, Hui-Ju, Long, Daniel, Ackenhusen, Sarah E, Ramos, Johanna, Gao, Xiaohua, Nwosu, Zeribe C, Galban, Stefanie, Halbrook, Christopher J, Lombard, David B, Piwnica-Worms, David R, Ying, Haoqiang, Pasca di Magliano, Marina, Crawford, Howard C, Shah, Yatrik M, Lyssiotis, Costas A

Volltext

Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells von Schwartz, Andrew J., Goyert, Joshua W., Solanki, Sumeet, Kerk, Samuel A., Chen, Brandon, Castillo, Cristina, Hsu, Peggy P., Do, Brian T., Singhal, Rashi, Dame, Michael K., Lee, Ho-Joon, Spence, Jason R., Lakhal-Littleton, Samira, Vander Heiden, Matthew G., Lyssiotis, Costas A., Xue, Xiang, Shah, Yatrik M.

Volltext

Spotlight on GOT2 in Cancer Metabolism von Kerk, Samuel A, Garcia-Bermudez, Javier, Birsoy, Kivanc, Sherman, Mara H, Shah, Yatrik M, Lyssiotis, Costas A

Volltext

Therapeutic Inhibition of the MDM2-p53 Interaction Prevents Recurrence of Adenoid Cystic Carcinomas von Nör, Felipe, Warner, Kristy A, Zhang, Zhaocheng, Acasigua, Gerson A, Pearson, Alexander T, Kerk, Samuel A, Helman, Joseph I, Sant'Ana Filho, Manoel, Wang, Shaomeng, Nör, Jacques E

Volltext

5T4-Targeted Therapy Ablates Cancer Stem Cells and Prevents Recurrence of Head and Neck Squamous Cell Carcinoma von Kerk, Samuel A, Finkel, Kelsey A, Pearson, Alexander T, Warner, Kristy A, Zhang, Zhaocheng, Nör, Felipe, Wagner, Vivian P, Vargas, Pablo A, Wicha, Max S, Hurt, Elaine M, Hollingsworth, Robert E, Tice, David A, Nör, Jacques E

Volltext

Extrinsic KRAS Signaling Shapes the Pancreatic Microenvironment Through Fibroblast Reprogramming von Velez-Delgado, Ashley, Donahue, Katelyn L., Brown, Kristee L., Du, Wenting, Irizarry-Negron, Valerie, Menjivar, Rosa E., Lasse Opsahl, Emily L., Steele, Nina G., The, Stephanie, Lazarus, Jenny, Sirihorachai, Veerin R., Yan, Wei, Kemp, Samantha B., Kerk, Samuel A., Bollampally, Murali, Yang, Sion, Scales, Michael K., Avritt, Faith R., Lima, Fatima, Lyssiotis, Costas A., Rao, Arvind, Crawford, Howard C., Bednar, Filip, Frankel, Timothy L., Allen, Benjamin L., Zhang, Yaqing, Pasca di Magliano, Marina

Volltext

Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition von Garner, Amanda L, Lorenz, Daniel A, Sandoval, Jorge, Gallagher, Erin E, Kerk, Samuel A, Kaur, Tanpreet, Menon, Arya

Volltext

Ketotherapy: Cutting carbs to treat cancer von Radyk, Megan D., Kerk, Samuel A., Lyssiotis, Costas A.

Volltext