Mitochondrial Uncoupling and the Warburg Effect: Molecular Basis for the Reprogramming of Cancer Cell Metabolism von SAMUDIO, Ismael, FIEGL, Michael, ANDREEFF, Michael

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Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML von Zeng, Zhihong, Xi Shi, Yue, Samudio, Ismael J., Wang, Rui-Yu, Ling, Xiaoyang, Frolova, Olga, Levis, Mark, Rubin, Joshua B., Negrin, Robert R., Estey, Elihu H., Konoplev, Sergej, Andreeff, Michael, Konopleva, Marina

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Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction von Samudio, Ismael, Harmancey, Romain, Fiegl, Michael, Kantarjian, Hagop, Konopleva, Marina, Korchin, Borys, Kaluarachchi, Kumar, Bornmann, William, Duvvuri, Seshagiri, Taegtmeyer, Heinrich, Andreeff, Michael

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Effects of the breed, sex and age on cellular content and growth factor release from equine pure-platelet rich plasma and pure-platelet rich gel von Giraldo, Carlos E, López, Catalina, Álvarez, María E, Samudio, Ismael J, Prades, Marta, Carmona, Jorge U

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Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML von Zeng, Zhihong, Sarbassov, Dos D., Samudio, Ismael J., Yee, Karen W.L., Munsell, Mark F., Ellen Jackson, C., Giles, Francis J., Sabatini, David M., Andreeff, Michael, Konopleva, Marina

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MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy von Kojima, Kensuke, Konopleva, Marina, Samudio, Ismael J., Shikami, Masato, Cabreira-Hansen, Maria, McQueen, Teresa, Ruvolo, Vivian, Tsao, Twee, Zeng, Zhihong, Vassilev, Lyubomir T., Andreeff, Michael

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Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias von Zeng, Zhihong, Samudio, Ismael J, Munsell, Mark, An, Jing, Huang, Ziwei, Estey, Elihu, Andreeff, Michael, Konopleva, Marina

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Resistin promotes smooth muscle cell proliferation through activation of extracellular signal-regulated kinase 1/2 and phosphatidylinositol 3-kinase pathways von Calabro, Paolo, Samudio, Ismael, Willerson, James T, Yeh, Edward T H

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Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia von Konopleva, Marina, Contractor, Rooha, Tsao, Twee, Samudio, Ismael, Ruvolo, Peter P., Kitada, Shinichi, Deng, Xingming, Zhai, Dayong, Shi, Yue-Xi, Sneed, Thomas, Verhaegen, Monique, Soengas, Maria, Ruvolo, Vivian R., McQueen, Teresa, Schober, Wendy D., Watt, Julie C., Jiffar, Tilahun, Ling, Xiaoyang, Marini, Frank C., Harris, David, Dietrich, Martin, Estrov, Zeev, McCubrey, James, May, W. Stratford, Reed, John C., Andreeff, Michael

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Pre-Existing HSV-1 Immunity Enhances Anticancer Efficacy of a Novel Immune-Stimulating Oncolytic Virus von Ding, Jun, Murad, Yanal M, Sun, Yi, Lee, I-Fang, Samudio, Ismael, Liu, Xiaohu, Jia, William Wei-Guo, Zhao, Ronghua

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3,3′-Diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5 von Abdelrahim, Maen, Newman, Kristen, Vanderlaag, Kathy, Samudio, Ismael, Safe, Stephen

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CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure von Fiegl, Michael, Samudio, Ismael, Clise-Dwyer, Karen, Burks, Jared K., Mnjoyan, Zakar, Andreeff, Michael

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Oncolytic virotherapy in hepato‐bilio‐pancreatic cancer: The key to breaking the log jam? von Li, Yuwei, Shen, Yinan, Zhao, Ronghua, Samudio, Ismael, Jia, William, Bai, Xueli, Liang, Tingbo

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Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment von Frolova, Olga, Samudio, Ismael, Benito, Juliana Maria, Jacamo, Rodrigo, Kornblau, Steven M., Markovic, Ana, Schober, Wendy, Lu, Hongbo, Qiu, Yi Hua, Buglio, Daniela, McQueen, Teresa, Pierce, Sherry, Shpall, Elizabeth J., Konoplev, Sergej, Thomas, Deborah, Kantarjian, Hagop, Lock, Richard, Andreeff, Michael, Konopleva, Marina

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UV-inactivated HSV-1 potently activates NK cell killing of leukemic cells von Samudio, Ismael, Rezvani, Katayoun, Shaim, Hila, Hofs, Elyse, Ngom, Mor, Bu, Luke, Liu, Guoyu, Lee, Jason T.C., Imren, Suzan, Lam, Vivian, Poon, Grace F.T., Ghaedi, Maryam, Takei, Fumio, Humphries, Keith, Jia, William, Krystal, Gerald

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All Trans Retinoic Acid, Transforming Growth Factor β and Prostaglandin E2 in Mouse Plasma Synergize with Basophil-Secreted Interleukin-4 to M2 Polarize Murine Macrophages von Ho, Victor W, Hofs, Elyse, Elisia, Ingrid, Lam, Vivian, Hsu, Brian E, Lai, June, Luk, Beryl, Samudio, Ismael, Krystal, Gerald

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Induction of Durable Antitumor Response by a Novel Oncolytic Herpesvirus Expressing Multiple Immunomodulatory Transgenes von Chouljenko, Dmitry V., Ding, Jun, Lee, I-Fang, Murad, Yanal M., Bu, Xuexian, Liu, Guoyu, Delwar, Zahid, Sun, Yi, Yu, Sheng, Samudio, Ismael, Zhao, Ronghua, Jia, William Wei-Guo

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Concomitant Inhibition of MDM2 and Bcl-2 Protein Function Synergistically Induce Mitochondrial Apoptosis in AML von Kojima, Kensuke, Konopleva, Marina, Samudio, Ismael J, Schober, Wendy D, Bornmann, William, Andreeff, Michael

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Mitogen-activated protein kinase kinase inhibition enhances nuclear proapoptotic function of p53 in acute myelogenous leukemia cells von KOJIMA, Kensuke, KONOPLEVA, Marina, SAMUDIO, Ismael J, RUVOLO, Vivian, ANDREEFF, Michael

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Targeting carcinoembryonic antigen-expressing tumors using a novel transcriptional and translational dual-regulated oncolytic herpes simplex virus type 1 von Chouljenko, Dmitry V., Murad, Yanal M., Lee, I-Fang, Delwar, Zahid, Ding, Jun, Liu, Guoyu, Liu, Xiaohu, Bu, Xuexian, Sun, Yi, Samudio, Ismael, Jia, William Wei-Guo

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