Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs von Yelshanskaya, Maria V., Singh, Appu K., Sampson, Jared M., Narangoda, Chamali, Kurnikova, Maria, Sobolevsky, Alexander I.

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Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals von Gorny, Miroslaw K, Pan, Ruimin, Williams, Constance, Wang, Xiao-Hong, Volsky, Barbara, O'Neal, Timothy, Spurrier, Brett, Sampson, Jared M, Li, Liuzhe, Seaman, Michael S, Kong, Xiang-Peng, Zolla-Pazner, Susan

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Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans von Pan, Ruimin, Sampson, Jared M, Chen, Yuxin, Vaine, Michael, Wang, Shixia, Lu, Shan, Kong, Xiang-Peng

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Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains von Zhou, Tongqing, Tsybovsky, Yaroslav, Gorman, Jason, Rapp, Micah, Cerutti, Gabriele, Chuang, Gwo-Yu, Katsamba, Phinikoula S., Sampson, Jared M., Schön, Arne, Bimela, Jude, Boyington, Jeffrey C., Nazzari, Alexandra, Olia, Adam S., Shi, Wei, Sastry, Mallika, Stephens, Tyler, Stuckey, Jonathan, Teng, I-Ting, Wang, Pengfei, Wang, Shuishu, Zhang, Baoshan, Friesner, Richard A., Ho, David D., Mascola, John R., Shapiro, Lawrence, Kwong, Peter D.

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Free Energy Perturbation Calculations of Mutation Effects on SARS-CoV-2 RBD::ACE2 Binding Affinity von Sergeeva, Alina P., Katsamba, Phinikoula S., Liao, Junzhuo, Sampson, Jared M., Bahna, Fabiana, Mannepalli, Seetha, Morano, Nicholas C., Shapiro, Lawrence, Friesner, Richard A., Honig, Barry

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A Method for Treating Significant Conformational Changes in Alchemical Free Energy Simulations of Protein–Ligand Binding von Liao, Junzhuo, Sergeeva, Alina P., Harder, Edward D., Wang, Lingle, Sampson, Jared M., Honig, Barry, Friesner, Richard A.

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Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120 von Spurrier, Brett, Sampson, Jared M., Totrov, Maxim, Li, Huiguang, O'Neal, Timothy, Williams, Constance, Robinson, James, Gorny, Miroslaw K., Zolla-Pazner, Susan, Kong, Xiang-Peng

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Novel Insights into the Mode of Inhibition of Class A SHV-1 β-Lactamases Revealed by Boronic Acid Transition State Inhibitors von Ke, Wei, Sampson, Jared M, Ori, Claudia, Prati, Fabio, Drawz, Sarah M, Bethel, Christopher R, Bonomo, Robert A, van den Akker, Focco

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Ligand-Dependent Disorder of the Ω Loop Observed in Extended-Spectrum SHV-Type β-Lactamase von SAMPSON, Jared M, WEI KE, BETHEL, Christopher R, PAGADALA, S. R. R, NOTTINGHAM, Michael D, BONOMO, Robert A, BUYNAK, John D, VAN DEN AKKER, Focco

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Rationally Designed Immunogens Targeting HIV-1 gp120 V1V2 Induce Distinct Conformation-Specific Antibody Responses in Rabbits von Jiang, Xunqing, Totrov, Max, Li, Wei, Sampson, Jared M, Williams, Constance, Lu, Hong, Wu, Xueling, Lu, Shan, Wang, Shixia, Zolla-Pazner, Susan, Kong, Xiang-Peng

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Robust Prediction of Relative Binding Energies for Protein–Protein Complex Mutations Using Free Energy Perturbation Calculations von Sampson, Jared M., Cannon, Daniel A., Duan, Jianxin, Epstein, Jordan C.K., Sergeeva, Alina P., Katsamba, Phinikoula S., Mannepalli, Seetha M., Bahna, Fabiana A., Adihou, Hélène, Guéret, Stéphanie M., Gopalakrishnan, Ranganath, Geschwindner, Stefan, Rees, D. Gareth, Sigurdardottir, Anna, Wilkinson, Trevor, Dodd, Roger B., De Maria, Leonardo, Mobarec, Juan Carlos, Shapiro, Lawrence, Honig, Barry, Buchanan, Andrew, Friesner, Richard A., Wang, Lingle

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Basic Residues at Position 11 of α‑Conotoxin LvIA Influence Subtype Selectivity between α3β2 and α3β4 Nicotinic Receptors via an Electrostatic Mechanism von Haufe, Yves, Kuruva, Veeresh, Samanani, Ziyana, Lokaj, Gonxhe, Kamnesky, Guy, Shadamarshan, PranavKumar, Shahoei, Rezvan, Katz, Dana, Sampson, Jared M., Pusch, Michael, Brik, Ashraf, Nicke, Annette, Leffler, Abba E.

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Design, Synthesis, and Crystal Structures of 6-Alkylidene-2′-Substituted Penicillanic Acid Sulfones as Potent Inhibitors of Acinetobacter baumannii OXA-24 Carbapenemase von Bou, German, Santillana, Elena, Sheri, Anjaneyulu, Beceiro, Alejandro, Sampson, Jared M, Kalp, Matthew, Bethel, Christopher R, Distler, Anne M, Drawz, Sarah M, Pagadala, Sundar Ram Reddy, van den Akker, Focco, Bonomo, Robert A, Romero, Antonio, Buynak, John D

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Structure-Based Functional Characterization of Repressor of Toxin (Rot), a Central Regulator of Staphylococcus aureus Virulence von Killikelly, April, Benson, Meredith A, Ohneck, Elizabeth A, Sampson, Jared M, Jakoncic, Jean, Spurrier, Brett, Torres, Victor J, Kong, Xiang-Peng

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Crystal Structure of a Preacylation Complex of the β‑Lactamase Inhibitor Sulbactam Bound to a Sulfenamide Bond-Containing Thiol-β-lactamase von Rodkey, Elizabeth A, Drawz, Sarah M, Sampson, Jared M, Bethel, Christopher R, Bonomo, Robert A, van den Akker, Focco

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Skin tattooing as a novel approach for DNA vaccine delivery von Chiu, Yung-Nung, Sampson, Jared M, Jiang, Xunqing, Zolla-Pazner, Susan B, Kong, Xiang-Peng

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The Importance of the trans-Enamine Intermediate as a β-Lactamase Inhibition Strategy Probed in Inhibitor-Resistant SHV β-Lactamase Variants von Ke, Wei, Rodkey, Elizabeth A., Sampson, Jared M., Skalweit, Marion J., Sheri, Anjaneyulu, Pagadala, Sundar Ram Reddy, Nottingham, Michael D., Buynak, John D., Bonomo, Robert A., van den Akker, Focco

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Skin Tattooing As A Novel Approach For DNA Vaccine Delivery von Chiu, Yung-Nung, Sampson, Jared M., Jiang, Xunqing, Zolla-Pazner, Susan B., Kong, Xiang-Peng

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β-Lactamase Inhibition: Mechanistic Details and Novel Inhibitors von Rodkey, Elizabeth A., Sampson, Jared M., Kalp, Matthew, Bethel, Christopher R., Buynak, John D., Carey, Paul R., Bonomo, Robert A., van, Focco, Akker, den

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Structural Analysis of Human and Macaque Monoclonal Antibodies 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120 von Spurrier, Brett, Sampson, Jared M., Totrov, Maxim, Li, Huiguang, O'Neal, Timothy, Williams, Constance, Robinson, James, Gorny, Miroslaw K., Zolla-Pazner, Susan, Kong, Xiang-Peng

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