Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls von Witten, Daniela, Tibshirani, Robert, Gu, Sam Guoping, Fire, Andrew, Lui, Weng-Onn

Volltext

Caenorhabditis elegans nuclear RNAi factor SET-32 deposits the transgenerational histone modification, H3K23me3 von Schwartz-Orbach, Lianna, Zhang, Chenzhen, Sidoli, Simone, Amin, Richa, Kaur, Diljeet, Zhebrun, Anna, Ni, Julie, Gu, Sam G

Volltext

Complex coding of endogenous siRNA, transcriptional silencing and H3K9 methylation on native targets of germline nuclear RNAi in C. elegans von Ni, Julie Zhouli, Chen, Esteban, Gu, Sam Guoping

Volltext

A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortality von Buckley, Bethany A., Burkhart, Kirk B., Gu, Sam Guoping, Spracklin, George, Kershner, Aaron, Fritz, Heidi, Kimble, Judith, Fire, Andrew, Kennedy, Scott

Volltext

Field-Based Capacitance Modeling for Sub-65-nm On-Chip Interconnect von Wei Zhao, Xia Li, Sam Gu, Kang, S.H., Nowak, M.M., Yu Cao

Volltext

MORC-1 Integrates Nuclear RNAi and Transgenerational Chromatin Architecture to Promote Germline Immortality von Weiser, Natasha E., Yang, Danny X., Feng, Suhua, Kalinava, Natallia, Brown, Kristen C., Khanikar, Jayshree, Freeberg, Mallory A., Snyder, Martha J., Csankovszki, Györgyi, Chan, Raymond C., Gu, Sam G., Montgomery, Taiowa A., Jacobsen, Steven E., Kim, John K.

Volltext

Deletion of microRNA-80 activates dietary restriction to extend C. elegans healthspan and lifespan von Vora, Mehul, Shah, Mitalie, Ostafi, Silvana, Onken, Brian, Xue, Jian, Ni, Julie Zhouli, Gu, Sam, Driscoll, Monica

Volltext

Amplification of siRNA in Caenorhabditis elegans generates a transgenerational sequence-targeted histone H3 lysine 9 methylation footprint von Gu, Sam Guoping, Pak, Julia, Guang, Shouhong, Maniar, Jay M, Kennedy, Scott, Fire, Andrew

Volltext

The conformation of microRNA seed regions in native microRNPs is prearranged for presentation to mRNA targets von Lambert, Nicole J., Gu, Sam G., Zahler, Alan M.

Volltext

Chromatin-Associated Periodicity in Genetic Variation Downstream of Transcriptional Start Sites von Sasaki, Shin, Mello, Cecilia C, Shimada, Atsuko, Nakatani, Yoichiro, Hashimoto, Shin-ichi, Ogawa, Masako, Matsushima, Kouji, Gu, Sam Guoping, Kasahara, Masahiro, Ahsan, Budrul, Sasaki, Atsushi, Saito, Taro, Suzuki, Yutaka, Sugano, Sumio, Kohara, Yuji, Takeda, Hiroyuki, Fire, Andrew, Morishita, Shinichi

Volltext

C. elegans Heterochromatin Factor SET-32 Plays an Essential Role in Transgenerational Establishment of Nuclear RNAi-Mediated Epigenetic Silencing von Kalinava, Natallia, Ni, Julie Zhouli, Gajic, Zoran, Kim, Matthew, Ushakov, Helen, Gu, Sam Guoping

Volltext

Decoupling the downstream effects of germline nuclear RNAi reveals that H3K9me3 is dispensable for heritable RNAi and the maintenance of endogenous siRNA-mediated transcriptional s... von Kalinava, Natallia, Ni, Julie Zhouli, Peterman, Kimberly, Chen, Esteban, Gu, Sam Guoping

Volltext

A transgenerational role of the germline nuclear RNAi pathway in repressing heat stress-induced transcriptional activation in C. elegans von Ni, Julie Zhouli, Kalinava, Natallia, Chen, Esteban, Huang, Alex, Trinh, Thi, Gu, Sam Guoping

Volltext

Distributed probing of chromatin structure in vivo reveals pervasive chromatin accessibility for expressed and non-expressed genes during tissue differentiation in C. elegans von Sha, Ky, Gu, Sam G, Pantalena-Filho, Luiz C, Goh, Amy, Fleenor, Jamie, Blanchard, Daniel, Krishna, Chaya, Fire, Andrew

Volltext

The zinc transporter ZIPT-7.1 regulates sperm activation in nematodes von Zhao, Yanmei, Tan, Chieh-Hsiang, Krauchunas, Amber, Scharf, Andrea, Dietrich, Nicholas, Warnhoff, Kurt, Yuan, Zhiheng, Druzhinina, Marina, Gu, Sam Guoping, Miao, Long, Singson, Andrew, Ellis, Ronald E, Kornfeld, Kerry

Volltext

The transcription start site landscape of C. elegans von Saito, Taro Leo, Hashimoto, Shin-ichi, Gu, Sam Guoping, Morton, J Jason, Stadler, Michael, Blumenthal, Thomas, Fire, Andrew, Morishita, Shinichi

Volltext

Partitioning the C. elegans genome by nucleosome modification, occupancy, and positioning von Gu, Sam Guoping, Fire, Andrew

Volltext

The people behind the papers - Zoran Gajic, Diljeet Kaur, Julie Ni and Sam Gu

Volltext

Unusual DNA packaging characteristics in endoreduplicated Caenorhabditis elegans oocytes defined by in vivo accessibility to an endogenous nuclease activity von Gu, Sam, Goszczynski, Barbara, McGhee, James D, Fire, Andrew Z

Volltext

Distinct ribonucleoprotein reservoirs for microRNA and siRNA populations in C. elegans von Gu, Sam G, Pak, Julia, Barberan-Soler, Sergio, Ali, Mustapha, Fire, Andrew, Zahler, Alan M

Volltext