TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer von Byrd, Tiara T, Fousek, Kristen, Pignata, Antonella, Szot, Christopher, Samaha, Heba, Seaman, Steven, Dobrolecki, Lacey, Salsman, Vita S, Oo, Htoo Zarni, Bielamowicz, Kevin, Landi, Daniel, Rainusso, Nino, Hicks, John, Powell, Suzanne, Baker, Matthew L, Wels, Winfried S, Koch, Joachim, Sorensen, Poul H, Deneen, Benjamin, Ellis, Matthew J, Lewis, Michael T, Hegde, Meenakshi, Fletcher, Bradley S, St Croix, Brad, Ahmed, Nabil

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Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma von Hegde, Meenakshi, Joseph, Sujith K., Pashankar, Farzana, DeRenzo, Christopher, Sanber, Khaled, Navai, Shoba, Byrd, Tiara T., Hicks, John, Xu, Mina L., Gerken, Claudia, Kalra, Mamta, Robertson, Catherine, Zhang, Huimin, Shree, Ankita, Mehta, Birju, Dakhova, Olga, Salsman, Vita S., Grilley, Bambi, Gee, Adrian, Dotti, Gianpietro, Heslop, Helen E., Brenner, Malcolm K., Wels, Winfried S., Gottschalk, Stephen, Ahmed, Nabil

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CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression von Fousek, Kristen, Watanabe, Junji, Joseph, Sujith K., George, Ann, An, Xingyue, Byrd, Tiara T., Morris, Jessica S., Luong, Annie, Martínez-Paniagua, Melisa A., Sanber, Khaled, Navai, Shoba A., Gad, Ahmed Z., Salsman, Vita S., Mathew, Pretty R., Kim, Hye Na, Wagner, Dimitrios L., Brunetti, Lorenzo, Jang, Albert, Baker, Matthew L., Varadarajan, Navin, Hegde, Meenakshi, Kim, Yong-Mi, Heisterkamp, Nora, Abdel-Azim, Hisham, Ahmed, Nabil

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HER2-Specific T Cells Target Primary Glioblastoma Stem Cells and Induce Regression of Autologous Experimental Tumors von Ahmed, Nabil, Salsman, Vita S, Kew, Yvonne, Shaffer, Donald, Powell, Suzanne, Zhang, Yi J, Grossman, Robert G, Heslop, Helen E, Gottschalk, Stephen

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Targeting GBM with an Oncolytic Picornavirus SVV-001 alone and in combination with fractionated Radiation in a Novel Panel of Orthotopic PDX models von Zhang, Huiyuan, Du, Yuchen, Qi, Lin, Xiao, Sophie, Braun, Frank K, Kogiso, Mari, Huang, Yulun, Huang, Frank, Abdallah, Aalaa, Suarez, Milagros, Karthick, Sekar, Ahmed, Nabil M, Salsman, Vita S, Baxter, Patricia A, Su, Jack M, Brat, Daniel J, Hellenbeck, Paul L, Teo, Wan-Yee, Patel, Akash J, Li, Xiao-Nan

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A homing system targets therapeutic T cells to brain cancer von Samaha, Heba, Pignata, Antonella, Fousek, Kristen, Ren, Jun, Lam, Fong W., Stossi, Fabio, Dubrulle, Julien, Salsman, Vita S., Krishnan, Shanmugarajan, Hong, Sung-Ha, Baker, Matthew L., Shree, Ankita, Gad, Ahmed Z., Shum, Thomas, Fukumura, Dai, Byrd, Tiara T., Mukherjee, Malini, Marrelli, Sean P., Orange, Jordan S., Joseph, Sujith K., Sorensen, Poul H., Taylor, Michael D., Hegde, Meenakshi, Mamonkin, Maksim, Jain, Rakesh K., El-Naggar, Shahenda, Ahmed, Nabil

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Immunotherapy for Osteosarcoma: Genetic Modification of T cells Overcomes Low Levels of Tumor Antigen Expression von Ahmed, Nabil, Salsman, Vita S, Yvon, Eric, Louis, Chrystal U, Perlaky, Laszlo, Wels, Winfried S, Dishop, Meghan K, Kleinerman, Eugenie E, Pule, Martin, Rooney, Cliona M, Heslop, Helen E, Gottschalk, Stephen

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PiggyBac-mediated Cancer Immunotherapy Using EBV-specific Cytotoxic T-cells Expressing HER2-specific Chimeric Antigen Receptor von Nakazawa, Yozo, Huye, Leslie E, Salsman, Vita S, Leen, Ann M, Ahmed, Nabil, Rollins, Lisa, Dotti, Gianpietro, Gottschalk, Stephen M, Wilson, Matthew H, Rooney, Cliona M

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Crosstalk between medulloblastoma cells and endothelium triggers a strong chemotactic signal recruiting T lymphocytes to the tumor microenvironment von Salsman, Vita S, Chow, Kevin K H, Shaffer, Donald R, Kadikoy, Huseyin, Li, Xiao-Nan, Gerken, Claudia, Perlaky, Laszlo, Metelitsa, Leonid S, Gao, Xiuhua, Bhattacharjee, Meena, Hirschi, Karen, Heslop, Helen E, Gottschalk, Stephen, Ahmed, Nabil

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Autologous HER2-specific CAR T cells after lymphodepletion for advanced sarcoma: a phase 1 trial von Hegde, Meenakshi, Navai, Shoba, DeRenzo, Christopher, Joseph, Sujith K, Sanber, Khaled, Wu, Mengfen, Gad, Ahmed Z, Janeway, Katherine A, Campbell, Matthew, Mullikin, Dolores, Nawas, Zeid, Robertson, Catherine, Mathew, Pretty R, Zhang, Huimin, Mehta, Birju, Bhat, Raksha R, Major, Angela, Shree, Ankita, Gerken, Claudia, Kalra, Mamta, Chakraborty, Rikhia, Thakkar, Sachin G, Dakhova, Olga, Salsman, Vita S, Grilley, Bambi, Lapteva, Natalia, Gee, Adrian, Dotti, Gianpietro, Bao, Riyue, Salem, Ahmed Hamed, Wang, Tao, Brenner, Malcolm K, Heslop, Helen E, Wels, Winfried S, Hicks, M John, Gottschalk, Stephen, Ahmed, Nabil

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Retraction Note: A homing system targets therapeutic T cells to brain cancer von Samaha, Heba, Pignata, Antonella, Fousek, Kristen, Ren, Jun, Lam, Fong W., Stossi, Fabio, Dubrulle, Julien, Salsman, Vita S., Krishnan, Shanmugarajan, Hong, Sung-Ha, Baker, Matthew L., Shree, Ankita, Gad, Ahmed Z., Shum, Thomas, Fukumura, Dai, Byrd, Tiara T., Mukherjee, Malini, Marrelli, Sean P., Orange, Jordan S., Joseph, Sujith K., Sorensen, Poul H., Taylor, Michael D., Hegde, Meenakshi, Mamonkin, Maksim, Jain, Rakesh K., El-Naggar, Shahenda, Ahmed, Nabil

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Glioma cells display complex cell surface topographies that resist the actions of cytolytic effector lymphocytes von Hoa, Neil, Ge, Lisheng, Kuznetsov, Yurii, McPherson, Alex, Cornforth, Andrew N, Pham, Jimmy T H, Myers, Michael P, Ahmed, Nabil, Salsman, Vita S, Lamb, Jr, Lawrence S, Bowersock, Joscelyn E, Hu, Yuanjie, Zhou, Yi-Hong, Jadus, Martin R

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Modulation of inhibitory signals in CAR T cells leads to improved activity against glioblastoma von Sanber, Khaled, Nawas, Zeid, Salsman, Vita, Gad, Ahmed, Matthew, Pretty, Lee, Ciaran, Joseph, Sujith, Ahmed, Nabil, Hegde, Meenakshi

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Abstract 2173: CRISPR-Cas9 gene editing of inhibitory receptor signaling pathways improves CAR T cell activity against glioblastoma von Sanber, Khaled, Nawas, Zeid, Salsman, Vita, Gad, Ahmed, Matthew, Pretty Rose, Landi, Daniel, Lee, Ciaran, Sengal, Amel, Chakraborty, Rikhia, Joseph, Sujith, Nabil, Ahmed, Hegde, Meenakshi

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Abstract 1151: CD6 isoforms improve CAR T cell fitness von Morris, Jessica S., Gad, Ahmed Z., Godret-Miertschin, Lea M., Fleischmann, Ryan, Salsman, Vita, Joseph, Sujith K., Ahmed, Nabil

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Abstract LB-147: Administration of HER2-CAR T cells after lymphodepletion safely improves T cell expansion and induces clinical responses in patients with advanced sarcomas von Navai, Shoba A., Derenzo, Christopher, Joseph, Sujith, Sanber, Khaled, Byrd, Tiara, Zhang, Huimin, Mata, Melinda, Gerken, Claudia, Shree, Ankita, Mathew, Pretty R., Dakhova, Olga, Salsman, Vita, Hicks, John, Yi, Zhongzhen, Wu, Meng-Fen, Wang, Tao, Grilley, Bambi, Rooney, Cliona, Brenner, Malcom, Heslop, Helen, Gee, Adrian, Gottschalk, Stephen, Ahmed, Nabil, Hegde, Meenakshi

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Generation of Polyclonal CMV-specific T Cells for the Adoptive Immunotherapy of Glioblastoma von GHAZI, Alexia, ASHOORI, Aidin, HEGDE, Meenakshi, LEEN, Ann M, BOLLARD, Catherine M, ROONEY, Cliona M, HESLOP, Helen E, GOTTSCHALK, Stephen, AHMED, Nabil, HANLEY, Patrick J, BRAWLEY, Vita S, SHAFFER, Donald R, KEW, Yvonne, POWELL, Suzanne Z, GROSSMAN, Robert, GRADA, Zakaria, SCHEURER, Michael E

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Primary medulloblastomas express functional CD1d and can be targeted for immunotherapy with NKT cells (156.25) von Liu, Daofeng, Song, Liping, Salsman, Vita, Gao, Xiuhua, Wei, Jie, Teo, Wanyee, Lau, Ching, Ahmed, Nabil, Metelitsa, Leonid

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Targeting Tumor Heterogeneity in Glioblastoma: Bispecific T Cells Exhibit Enhanced Effector Functions and Offset Antigen Loss Escape Variants von Hegde, Meenakshi, Yvon, Eric, Ashoori, Aidin, Mukherjee, Malini, Chow, Kevin KH, Gerken, Claudia, Salsman, Vita S, Heslop, Helen E, Gottschalk, Stephen, Ahmed, Nabil

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