FoxO transcription factors in the maintenance of cellular homeostasis during aging von Salih, Dervis AM, Brunet, Anne

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Microglia contribute to the production of the amyloidogenic ABri peptide in familial British dementia von Arber, Charles, Casey, Jackie M., Crawford, Samuel, Rambarack, Naiomi, Yaman, Umran, Wiethoff, Sarah, Augustin, Emma, Piers, Thomas M., Price, Matthew, Rostagno, Agueda, Ghiso, Jorge, Lewis, Patrick A., Revesz, Tamas, Hardy, John, Pocock, Jennifer M., Houlden, Henry, Schott, Jonathan M., Salih, Dervis A., Lashley, Tammaryn, Wray, Selina

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A Genome-wide Gene-Expression Analysis and Database in Transgenic Mice during Development of Amyloid or Tau Pathology von Matarin, Mar, Salih, Dervis A., Yasvoina, Marina, Cummings, Damian M., Guelfi, Sebastian, Liu, Wenfei, Nahaboo Solim, Muzammil A., Moens, Thomas G., Paublete, Rocio Moreno, Ali, Shabinah S., Perona, Marina, Desai, Roshni, Smith, Kenneth J., Latcham, Judy, Fulleylove, Michael, Richardson, Jill C., Hardy, John, Edwards, Frances A.

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Prodromal neuroinflammatory, cholinergic and metabolite dysfunction detected by PET and MRS in the TgF344-AD transgenic rat model of AD: a collaborative multi-modal study von Chaney, Aisling M, Lopez-Picon, Francisco R, Serrière, Sophie, Wang, Rui, Bochicchio, Daniela, Webb, Samuel D, Vandesquille, Matthias, Harte, Michael K, Georgiadou, Christina, Lawrence, Catherine, Busson, Julie, Vercouillie, Johnny, Tauber, Clovis, Buron, Frédéric, Routier, Sylvain, Reekie, Tristan, Snellman, Anniina, Kassiou, Michael, Rokka, Johanna, Davies, Karen E, Rinne, Juha O, Salih, Dervis A, Edwards, Frances A, Orton, Llwyd D, Williams, Stephen R, Chalon, Sylvie, Boutin, Hervé

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Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions von Liu, Wenfei, Taso, Orjona, Wang, Rui, Bayram, Sevinc, Graham, Andrew C, Garcia-Reitboeck, Pablo, Mallach, Anna, Andrews, William D, Piers, Thomas M, Botia, Juan A, Pocock, Jennifer M, Cummings, Damian M, Hardy, John, Edwards, Frances A, Salih, Dervis A

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Knock-in models related to Alzheimer's disease: synaptic transmission, plaques and the role of microglia von Benitez, Diana P, Jiang, Shenyi, Wood, Jack, Wang, Rui, Hall, Chloe M, Peerboom, Carlijn, Wong, Natalie, Stringer, Katie M, Vitanova, Karina S, Smith, Victoria C, Joshi, Dhaval, Saito, Takashi, Saido, Takaomi C, Hardy, John, Hanrieder, Jörg, De Strooper, Bart, Salih, Dervis A, Tripathi, Takshashila, Edwards, Frances A, Cummings, Damian M

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A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene von Magusali, Naciye, Graham, Andrew C, Piers, Thomas M, Panichnantakul, Pantila, Yaman, Umran, Shoai, Maryam, Reynolds, Regina H, Botia, Juan A, Brookes, Keeley J, Guetta-Baranes, Tamar, Bellou, Eftychia, Bayram, Sevinc, Sokolova, Dimitra, Ryten, Mina, Sala Frigerio, Carlo, Escott-Price, Valentina, Morgan, Kevin, Pocock, Jennifer M, Hardy, John, Salih, Dervis A

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A FOXO-Pak1 transcriptional pathway controls neuronal polarity von de la Torre-Ubieta, Luis, Gaudillière, Brice, Yang, Yue, Ikeuchi, Yoshiho, Yamada, Tomoko, DiBacco, Sara, Stegmüller, Judith, Schüller, Ulrich, Salih, Dervis A, Rowitch, David, Brunet, Anne, Bonni, Azad

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IGF-independent effects of insulin-like growth factor binding protein-5 (Igfbp5) in vivo von Tripathi, Gyanendra, Salih, Dervis A.M, Drozd, Anja C, Cosgrove, Ruth A, Cobb, Laura J, Pell, Jennifer M

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FoxO3 Regulates Neural Stem Cell Homeostasis von Renault, Valérie M., Rafalski, Victoria A., Morgan, Alex A., Salih, Dervis A.M., Brett, Jamie O., Webb, Ashley E., Villeda, Saul A., Thekkat, Pramod U., Guillerey, Camille, Denko, Nicholas C., Palmer, Theo D., Butte, Atul J., Brunet, Anne

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Human longevity and Alzheimer's disease variants act via microglia and oligodendrocyte gene networks von Graham, Andrew C, Bellou, Eftychia, Harwood, Janet C, Yaman, Umran, Celikag, Meral, Magusali, Naciye, Rambarack, Naiomi, Botia, Juan A, Sala Frigerio, Carlo, Hardy, John, Escott-Price, Valentina, Salih, Dervis A

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FoxO6 regulates memory consolidation and synaptic function von Salih, Dervis A M, Rashid, Asim J, Colas, Damien, de la Torre-Ubieta, Luis, Zhu, Ruo P, Morgan, Alexander A, Santo, Evan E, Ucar, Duygu, Devarajan, Keerthana, Cole, Christina J, Madison, Daniel V, Shamloo, Mehrdad, Butte, Atul J, Bonni, Azad, Josselyn, Sheena A, Brunet, Anne

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TREM2-mediated activation of microglia breaks link between amyloid and tau von Hardy, John, Salih, Dervis

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First effects of rising amyloid-β in transgenic mouse brain: synaptic transmission and gene expression von Cummings, Damian M, Liu, Wenfei, Portelius, Erik, Bayram, Sevinç, Yasvoina, Marina, Ho, Sui-Hin, Smits, Hélène, Ali, Shabinah S, Steinberg, Rivka, Pegasiou, Chrysia-Maria, James, Owain T, Matarin, Mar, Richardson, Jill C, Zetterberg, Henrik, Blennow, Kaj, Hardy, John A, Salih, Dervis A, Edwards, Frances A

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Neuronal and Peripheral Pentraxins Modify Glutamate Release and may Interact in Blood-Brain Barrier Failure von Cummings, Damian M, Benway, Tiffanie A, Ho, Hinze, Tedoldi, Angelo, Fernandes Freitas, Monica M, Shahab, Lion, Murray, Christina E, Richard-Loendt, Angela, Brandner, Sebastian, Lashley, Tammaryn, Salih, Dervis A, Edwards, Frances A

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Insulin-Like Growth Factor-Binding Protein 5 (Igfbp5) Compromises Survival, Growth, Muscle Development, and Fertility in Mice von Dervis A. M. Salih, Tripathi, Gyanendra, Holding, Cathy, Tadge A. M. Szestak, Gonzalez, M. Ivelisse, Carter, Emma J., Cobb, Laura J., Eisemann, Joan E., Pell, Jennifer M., Berridge, Michael J.

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Insulin-Like Growth Factor-Binding Protein-5 Induces a Gender-Related Decrease in Bone Mineral Density in Transgenic Mice von Salih, Dervis A. M, Mohan, Subburaman, Kasukawa, Yuji, Tripathi, Gyanendra, Lovett, Fiona A, Anderson, Neil F, Carter, Emma J, Wergedal, Jon E, Baylink, David J, Pell, Jennifer M

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Genetic variability in response to amyloid beta deposition influences Alzheimer's disease risk von Salih, Dervis A, Bayram, Sevinc, Guelfi, Sebastian, Reynolds, Regina H, Shoai, Maryam, Ryten, Mina, Brenton, Jonathan W, Zhang, David, Matarin, Mar, Botia, Juan A, Shah, Runil, Brookes, Keeley J, Guetta-Baranes, Tamar, Morgan, Kevin, Bellou, Eftychia, Cummings, Damian M, Escott-Price, Valentina, Hardy, John

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Partitioning of IGFBP-5 actions in myogenesis: IGF-independent anti-apoptotic function von Cobb, Laura J, Salih, Dervis A M, Gonzalez, Ivelisse, Tripathi, Gyanendra, Carter, Emma J, Lovett, Fiona, Holding, Cathy, Pell, Jennifer M

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Whole genome analysis in APOE4 homozygotes identifies the DAB1-RELN pathway in Alzheimer's disease pathogenesis von Bracher-Smith, Matthew, Leonenko, Ganna, Baker, Emily, Crawford, Karen, Graham, Andrew C., Salih, Dervis A., Howell, Brian W., Hardy, John, Escott-Price, Valentina

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